The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Medication noncompliance and substance abuse among patients with schizophrenia
Abstract
OBJECTIVE: The study examined the effect of medication noncompliance and substance abuse on symptoms of schizophrenia. METHODS: Short-term inpatients with a diagnosis of schizophrenia were enrolled in a longitudinal outcomes study and continued to receive standard care after discharge. At baseline and six-month follow-up, Brief Psychiatric Rating Scale (BPRS) scores and data on subjects' reported medication compliance, drug and alcohol abuse, usual living arrangements, and observed side effects were obtained. The number of outpatient contacts during the follow-up period was obtained from medical records. Relationships between the dependent variables-medication noncompliance and follow-up BPRS scores-and the independent variables were analyzed using logistic and linear regression models. RESULTS: Medication noncompliance was significantly associated with substance abuse. Subjects who abused substances, had no outpatient contact, and were noncompliant with medication had significantly greater symptom severity than other groups. CONCLUSIONS: Substance abuse is strongly associated with medication noncompliance among patients with schizophrenia. The combination of substance abuse, medication noncompliance, and lack of outpatient contact appears to define a particularly high-risk group.
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Cites
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Cited by
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Gilmer, T. P., Dolder, C. R., Lacro, J. P., Folsom, D. P., Lindamer, L., Garcia, P., & Jeste, D. V. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.4.692 · Cited by 603
Dual diagnosis of substance abuse in schizophrenia: prevalence and impact on outcomes
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Disengagement from mental health services: A literature review
O’Brien, A., Fahmy, R., & Singh, S. P. (2009) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-008-0476-0 · Cited by 283
Substance abuse in schizophrenia: a review of the literature and a study of correlates in Sweden
Cantor-Graae, E., Nordström, L. G., & McNeil, T. F. (2001) · Schizophrenia Research · doi:10.1016/s0920-9964(00)00114-6 · Cited by 261
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Declared and undeclared substance use among emergency department patients: a population‐based study
Rockett, I. R. H., Putnam, S. L., Jia, H., & Smith, G. S. (2006) · Addiction · doi:10.1111/j.1360-0443.2006.01397.x · Cited by 125
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Martino, S., Carroll, K. M., Nich, C., & Rounsaville, B. J. (2006) · Addiction · doi:10.1111/j.1360-0443.2006.01554.x · Cited by 97
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Substance use and schizophrenia: adverse correlates in the CATIE study sample
Kerfoot, K. E., Rosenheck, R. A., Petrakis, I. L., Swartz, M. S., Keefe, R. S. E., McEvoy, J. P., & Stroup, T. S. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2011.07.032 · Cited by 70
Medication adherence among homeless patients: A pilot study of cell phone effectiveness
Burda, C., Haack, M., Duarte, A. C., & Alemi, F. (2012) · Journal of the American Academy of Nurse Practitioners · doi:10.1111/j.1745-7599.2012.00756.x · Cited by 50
Screening for psychiatric disorders in outpatients with DSM-IV substance use disorders
Zimmerman, M., Sheeran, T., Chelminski, I., & Young, D. (2004) · Journal of Substance Abuse Treatment · doi:10.1016/s0740-5472(03)00207-1 · Cited by 43
Alene, M., Wiese, M. D., Angamo, M. T., Bajorek, B. V., Yesuf, E. A., & Wabe, N. T. (2012) · BMC Clinical Pharmacology · doi:10.1186/1472-6904-12-10 · Cited by 34
Metadata
- Venue
- Psychiatric Services
- Published
- 1996-08-01
- Volume
- 47
- Issue
- 8
- Pages
- 853-858
- ISSN
- 0022-1597 (ISSN-L)
- 1075-2730
- 1557-9700
- OpenAlex
- W1629537514
- Cited by
- 330
- References
- 3
- FWCI
- 10.17
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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