Nodular Fasciitis: Differential Considerations and Current Management Strategies
Abstract
Nodular fasciitis (NF) typically presents as an enlarging soft tissue mass with imaging characteristics that may be suggestive of soft tissue sarcoma or desmoid tumor. This presentation can make a correct diagnosis and management of patients with NF a challenge. We report our recent experience with two cases of NF that were both referred with a diagnoses of “soft tissue sarcoma.” Patient 1 was a 46-year-old woman who had undergone breast augmentation and was referred with a rapidly growing firm mass on the left chest wall beneath the breast implant. Computed tomography of the chest noted the mass to be 8 cm X 11 cm in size displacing the implant laterally with no radiological involvement of the bony structures of the chest. Core biopsy was suggestive of inflammation only. Given the clinical suspicion of malignancy, the patient underwent resection of the mass with implant removal. Final pathology showed NF. Patient 2 was a 65-year-old woman referred with an enlarging tender 3-cm infraclavicular mass and a clinical diagnosis of “soft tissue sarcoma.” Preoperative biopsy suggested NF. The patient underwent complete excision, which confirmed the diagnosis. These cases highlight the clinical issues associated with management of patients with NF. Current approaches to evaluation, diagnosis, and treatment of NF are discussed.
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In most patients, nodular fasciitis or desmoid tumours are excluded from the differential diagnosis, because in general these patients do not present with a mass in or close to a scar, pain symptoms during menstruation or continuous pain symptoms, as patients in our study did.
“However, in most patients, nodular fasciitis or desmoid tumours are excluded from the differential diagnosis, because in general these patients do not present with a mass in or close to a scar, pain symptoms during menstruation or continuous pain symptoms [26], as patients in our study did.”
From Appearance of abdominal wall endometriosis on MR imaging (2010) · cites this paper as [26]
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Appearance of abdominal wall endometriosis on MR imaging
Busard, M. P. H., Mijatovic, V., van Kuijk, C., Hompes, P. G. A., & van Waesberghe, J. H. T. M. (2010) · European Radiology · doi:10.1007/s00330-009-1658-1 · Cited by 79 · see citing works
“However, in most patients, nodular fasciitis or desmoid tumours are excluded from the differential diagnosis, because in general these patients do not present with a mass in or close to a scar, pain symptoms during menstruation or continuous pain symptoms [26], as patients in our study did.”
Background
- Authors
- Grobmyer, S. R., Knapik, J. A., Foss, R. M., Copeland, E. M., & Hochwald, S. N.
- Affiliations
- University of Florida Health (US)
- Corresponding author
- Grobmyer, Stephen R.
- Venue
- The American Surgeon™
- Publisher
- SAGE Publications
- Published
- 2009-07
- Volume
- 75
- Issue
- 7
- Pages
- 610-614
- ISSN
- 0003-1348 (ISSN-L)
- 1555-9823
- OpenAlex
- W56294838
- Cited by
- 14
- References
- 50
- Citations by year
- 2020: 1 · 2017: 1 · 2016: 2 · 2015: 3 · 2014: 2 · 2013: 2 · 2012: 1
- FWCI
- 0.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Surgeon (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rheumatology › Soft tissue tumor case studies
- Health Sciences › Medicine › Pathology and Forensic Medicine › Breast Lesions and Carcinomas
- Health Sciences › Medicine › Pathology and Forensic Medicine › Soft tissue tumors and treatment
- Keywords
- nodular fasciitis, soft tissue sarcoma mimic, aggressive fibromatosis, differential diagnosis, breast augmentation complications, chest wall mass, surgical excision, implant removal
- MeSH terms
- Diagnosis, Differential, Fasciitis, Female, Humans, Middle Aged, Sarcoma
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