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Cited by 253Soft tissue tumor case studiesSoft tissue tumors and treatmentSarcoma Diagnosis and Treatment

Pathologic and MR Imaging Features of Benign Fibrous Soft-Tissue Tumors in Adults

Dinauer, Philip A., Brixey, Clark J., Moncur, Joel T., Fanburg-Smith, Julie C., Murphey, Mark D.·2007·RadioGraphics
DOI 10.1148/rg.271065065
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Abstract

Benign fibrous (fibroblastic or myofibroblastic) soft-tissue tumors are a heterogeneous group of fibrous lesions with widely varied anatomic locations, biologic behavior, and pathologic features. The four broad categories of fibrous proliferation are benign fibrous proliferations, fibromatoses, fibrosarcomas, and fibrous proliferations of infancy and childhood. The first two categories include nonaggressive fibroblastic lesions such as nodular fasciitis, as well as fibromatoses that demonstrate more aggressive biologic behavior (eg, desmoid tumors). In adults, fibrous tumors are among the most common soft-tissue lesions encountered in clinical practice. MR imaging can be useful for defining the intrinsic signal characteristics, size, and compartmental extension of these lesions. Histologic features of the tumor also may be depicted on T2-weighted MR images. Hypocellular fibrous tumors with dense collagenous components tend to have lower signal intensity on T2-weighted images than do lesions that are more cellular or that contain greater amounts of extracellular myxoid matrix. When interpreting MR images of soft-tissue masses in adults, radiologists should be aware of the clinical behavior, common sites of occurrence, and histopathologic and imaging features of the common benign fibrous soft-tissue tumors.

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  • We did not use intravenous contrast, as previous studies demonstrated enhancement of AWE lesions on post-contrast T1-weighted images was not specific.

    “We did not use intravenous contrast, as previous studies demonstrated enhancement of AWE lesions on post-contrast T1-weighted images was not specific [7, 31–33].”

    From Appearance of abdominal wall endometriosis on MR imaging (2010) · cites this paper as [33]

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Authors
Dinauer, P. A., Brixey, C. J., Moncur, J. T., Fanburg-Smith, J. C., & Murphey, M. D.
Affiliations
  • Uniformed Services University of the Health Sciences (US)
  • Walter Reed National Military Medical Center (US)
ORCID
Murphey, Mark D.
Venue
RadioGraphics
Publisher
Radiological Society of North America (RSNA)
Published
2007-01
Volume
27
Issue
1
Pages
173-187
ISSN
  • 0271-5333 (ISSN-L)
  • 1527-1323
DOI
10.1148/rg.271065065
OpenAlex
W2143458022
Cited by
253
References
70
Citations by year
2026: 9 · 2025: 9 · 2024: 11 · 2023: 13 · 2022: 18 · 2021: 14 · 2020: 21 · 2019: 11 · 2018: 16 · 2017: 19 · 2016: 7 · 2015: 15 · 2014: 15 · 2013: 19 · 2012: 12
FWCI
1.22
Type
journal article
Language
en
Open access
closed
Locations
  • Radiographics (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Rheumatology › Soft tissue tumor case studies
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Soft tissue tumors and treatment
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Sarcoma Diagnosis and Treatment
Keywords
fibroblast proliferation, fibrosarcoma, nodular fasciitis, aggressive fibromatosis, myofibroblastic tumor, histopathological features
MeSH terms
Adult, Biopsy, Diagnosis, Differential, Humans, Image Enhancement, Magnetic Resonance Imaging, Practice Patterns, Physicians', Soft Tissue Neoplasms, Practice Guidelines as Topic, Neoplasms, Fibrous Tissue

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