Oropharyngeal and Esophageal Swallowing Impairments: Their Association and the Predictive Value of the Modified Barium Swallow Impairment Profile and Combined Multichannel Intraluminal Impedance—Esophageal Manometry
Abstract
Objectives: Deglutition is a highly integrated process of neural signaling and coordinated muscular contraction that begins with bolus preparation in the oral cavity and ends with closure of the lower esophageal sphincter after bolus passage. The goal of this study was to examine the relationship between measures of oropharyngeal and esophageal swallow function. Methods: A retrospective review was performed of patients who underwent modified barium swallow study (MBSS) and multichannel intraluminal impedance–esophageal manometry (MII-EM) over 7 years at an academic institution. The MBSS was scored with the Modified Barium Swallow Impairment Profile (MBSImP). Associations between impairments as measured by the MBSImP and MII-EM were assessed with a 2-sided Fisher's exact test. Results: One hundred sixty-four patients met the inclusion criteria for the study. Comparison of MBSImPcomponent and oral and pharyngeal total regional scores to MII-EM scores revealed a significant association between abnormal esophageal clearance on MBSS (MBSImP component 17) and abnormal findings on MII-EM (p < 0.001). Delay in initiation of pharyngeal swallow (MBSImPcomponent 6) was significantly associated with abnormal esophageal clearance on MBSS (p = 0.023). Conclusions: Abnormal esophageal clearance on MBSS (MBSImP component 17) indicates a need for further esophageal testing. A functional interrelationship between abnormalities of oropharyngeal and esophageal swallowing does exist, illuminating the importance of thorough pharyngoesophageal examination for dysphagia symptoms.
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Abnormal esophageal clearance is correlated with abnormal findings on esophageal manometry with impedance.
“Subsequent studies determined that the MBSImP protocol does not prolong radiation exposure14 and that abnormal esophageal clearance is correlated with abnormal findings on esophageal manometry with impedance.15”
From Classification of high-resolution manometry data according to videofluoroscopic parameters using pattern recognition (2013) · cites this paper as [15]
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- Authors
- Gullung, J. L., Hill, E. G., Castell, D. O., & Martin-Harris, B.
- Affiliations
- Medical University of South Carolina (US)
- ORCID
- Hill, Elizabeth G.
- Venue
- Annals of Otology, Rhinology & Laryngology
- Publisher
- SAGE Publications
- Published
- 2012-11
- Volume
- 121
- Issue
- 11
- Pages
- 738-745
- ISSN
- 0003-4894 (ISSN-L)
- 1943-572X
- OpenAlex
- W2103607334
- Cited by
- 56
- References
- 23
- Citations by year
- 2026: 2 · 2025: 8 · 2024: 7 · 2023: 4 · 2022: 5 · 2021: 3 · 2020: 5 · 2019: 5 · 2018: 5 · 2017: 1 · 2016: 3 · 2015: 2 · 2014: 2 · 2013: 4
- FWCI
- 6.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Otology Rhinology & Laryngology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Health Professions › Speech and Hearing › Dysphagia Assessment and Management
- Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
- Health Sciences › Medicine › Physiology › Voice and Speech Disorders
- Keywords
- dysphagia, oropharyngeal swallowing, esophageal clearance, Modified Barium Swallow Impairment Profile, multichannel intraluminal impedance, esophageal manometry, predictive value
- MeSH terms
- Adult, Aged, Aged, 80 and over, Deglutition Disorders, Electrodiagnosis, Female, Humans, Male, Manometry, Middle Aged, Oropharynx, Predictive Value of Tests, Retrospective Studies, Severity of Illness Index, Electric Impedance, Esophageal Sphincter, Lower, Young Adult
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