Natural history of sudden sensorineural hearing loss
Abstract
This is a prospective in-depth study of patients with sudden idiopathic sensorineural hearing loss. We found that 65% recover completely to functional hearing levels spontaneously and independent of any type of medical treatment. The majority do so within 14 days and many within the first few days. Prognosis can be predicted according to the slope of the initial audiogram (low-frequency losses do better than high-frequency losses), hearing at 8 kHz, erythrocyte sedimentation rates, in some select instances spatial disorientation symptoms, and speech discrimination scores. There was a very poor correlation between hearing and vestibular test abnormalities, except hypoactive calories. There were no correlations with age (excepting the very elderly), with antecedent respiratory infections, hypertension, diabetes, or other chronic diseases. We conclude that there is a fundamental difference in the behavior of apical and basal cochlea losses, that hearing recovery is always better at low than at high frequencies, that because of the high spontaneous recovery rates, tympanotomies seeking peri-lymph fistulas should be delayed ten days unless there is a progressive hearing loss, and that none of the current recommended treatments, especially histamine, have any effect on the outcome.
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The population described herein likely benefited less from spontaneous recovery, which occurs within 14 days from symptom onset, and consequently had worse hearing recovery.
“The population described herein likely benefited less from spontaneous recovery, which occurs within 14 days from symptom onset, and as a consequence are associated with worse hearing recovery [14-17].”
From Intratympanic steroid administration and predictors of recovery in sudden sensorineural hearing loss (2025) · cites this paper as [16]
Spontaneous recovery occurs within 14 days from symptom onset.
“spontaneous recovery, which occurs within 14 days from symptom onset”
From Intratympanic steroid administration and predictors of recovery in sudden sensorineural hearing loss (2025) · cites this paper as [16]
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Clinical Practice Guideline: Sudden Hearing Loss (Update)
Chandrasekhar, S. S., Tsai Do, B. S., Schwartz, S. R., Bontempo, L. J., Faucett, E. A., Finestone, S. A., Hollingsworth, D. B., Kelley, D. M., Kmucha, S. T., Moonis, G., et al. (2019) · Otolaryngology–Head and Neck Surgery · doi:10.1177/0194599819859885 · Cited by 931 · see citing works
Chaushu, H., Ungar, O. J., Abu Eta, R., Handzel, O., Muhanna, N., & Oron, Y. (2023) · Clinical Otolaryngology · doi:10.1111/coa.14036 · Cited by 35 · see citing works
Hearing outcome of recurrent sudden deafness: Ipsilateral versus contralateral types
Kuo, Y.-L., & Young, Y.-H. (2012) · Acta Oto-Laryngologica · doi:10.3109/00016489.2011.642817 · Cited by 17 · see citing works
Intratympanic steroid administration and predictors of recovery in sudden sensorineural hearing loss
Kennedy, D. J., Williams, E., Wolf, L., Golden, J., Lana, A., Wiefels, M., Pyle, M., Yunis, V., & Hoffer, M. (2025) · PLOS One · doi:10.1371/journal.pone.0332809 · Cited by 4 · see citing works
- Authors
- Mattox, D. E., & Simmons, F. B.
- Affiliations
- Stanford, California
- Venue
- Annals of Otology, Rhinology & Laryngology
- Publisher
- SAGE Publications
- Published
- 1977-07
- Volume
- 86
- Issue
- 4
- Pages
- 463-480
- ISSN
- 0003-4894 (ISSN-L)
- 1943-572X
- OpenAlex
- W2070447196
- Cited by
- 833
- References
- 0
- Citations by year
- 2026: 19 · 2025: 30 · 2024: 50 · 2023: 22 · 2022: 26 · 2021: 35 · 2020: 33 · 2019: 38 · 2018: 31 · 2017: 32 · 2016: 35 · 2015: 24 · 2014: 34 · 2013: 36 · 2012: 36
- FWCI
- 5.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Otology Rhinology & Laryngology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hearing Loss and Rehabilitation
- Keywords
- sudden sensorineural hearing loss, idiopathic hearing loss, prognosis, low-frequency hearing loss, erythrocyte sedimentation rate, spatial disorientation, speech discrimination, vestibular dysfunction, caloric test, tympanotomy, histamine
- MeSH terms
- Adolescent, Adult, Age Factors, Aged, Audiometry, Auditory Threshold, Blood Sedimentation, Child, Cochlea, Deafness, Ear Diseases, Female, Hemorrhage, Humans, Labyrinth Diseases, Male, Middle Aged, Prognosis, Prospective Studies, Sex Factors, Space Perception, Time Factors, Vascular Diseases, Virus Diseases
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