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Efficacy of Fixed Combination Antibiotics versus Separate Components in Otitis Media: Effectiveness of Erythromycin Estolate, Triple Sulfonamide, Ampicillin, Erythromycin Estolate-Triple Sulfonamide, and Placebo in 280 Patients with Acute Otitis Media Under Two and One-Hal Years of Age
Abstract
Ampicillin and a fixed combination of erythromycin estolate-triple sulfonamide suspension proved equally effective in eradicating or ganisms and exudate in otitis media. Triple sulfonamide was not as effective as a number of other drugs tested for eliminating the pneu mococcus, and erythromycin estolate was not as effective as the fixed combination or ampicillin with Hemophilus influenzae.
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Citations
Cited by
The Diagnosis and Management of Acute Otitis Media
Lieberthal, A. S., Carroll, A. E., Chonmaitree, T., Ganiats, T. G., Hoberman, A., Jackson, M. A., Joffe, M. D., Miller, D. T., Rosenfeld, R. M., Sevilla, X. D., et al. (2013) · Pediatrics · doi:10.1542/peds.2012-3488 · Cited by 1,442
Natural history of untreated otitis media
Rosenfeld, R. M., & Kay, D. (2003) · The Laryngoscope · doi:10.1097/00005537-200310000-00004 · Cited by 428
Marchant, C. D. (1990) · The American Journal of Medicine · doi:10.1016/0002-9343(90)90255-c · Cited by 45
Metadata
- Authors
- Howie, V. M., & Ploussard, J. H.
- Venue
- Clinical Pediatrics
- Publisher
- SAGE Publications
- Published
- 1972-04
- Volume
- 11
- Issue
- 4
- Pages
- 205-214
- ISSN
- 0009-9228 (ISSN-L)
- 1938-2707
- OpenAlex
- W2167343646
- Cited by
- 169
- References
- 0
- FWCI
- 11.11
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Efficacy of Fixed Combination Antibiotics versus Separate Components in Otitis Media: Effectiveness of Erythromycin Estolate, Triple Sulfonamide, Ampicillin, Erythromycin Estolate-Triple Sulfonamide, and Placebo in 280 Patients with Acute Otitis Media Under Two and One-Hal Years of Age. https://app.cochat.ai/papers/10.1177/000992287201100407
- The paper
- Howie, V. M., & Ploussard, J. H. (1972). Efficacy of Fixed Combination Antibiotics versus Separate Components in Otitis Media: Effectiveness of Erythromycin Estolate, Triple Sulfonamide, Ampicillin, Erythromycin Estolate-Triple Sulfonamide, and Placebo in 280 Patients with Acute Otitis Media Under Two and One-Hal Years of Age. Clinical Pediatrics. https://doi.org/10.1177/000992287201100407
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
