The DOI matches its Crossref record.
Meta-analysis of Dysphagia and Aspiration Pneumonia in Frail Elders
Abstract
As part of a systematic literature review, a comprehensive literature search was carried out to identify risk factors for aspiration pneumonia in frail older people. A prominent risk factor found was dysphagia with evidence level 2a, according to the Oxford Centre for Evidence-based Medicine Levels of Evidence. Subsequently, a meta-analysis of 4 cohort, 1 case-cohort, and 1 case-control study on dysphagia as a risk factor of aspiration pneumonia in frail older people was performed. Using a random effects model, we found a positive correlation between dysphagia and aspiration pneumonia: OR = 9.84; 95%CI = 4.15 - 23.33 (test for statistical homogeneity: p < 0.001). Then, a subgroup meta-analysis was performed with 4 cohort studies, all including patients with a cerebrovascular disease. Once again, a positive correlation was found between dysphagia and aspiration pneumonia: OR = 12.93; 95%CI = 8.61 - 19.44. The test for statistical homogeneity revealed no statistically significant result (p = 0.15). It was concluded that dysphagia is a serious risk factor for aspiration pneumonia in frail older people, particularly in those suffering from a cerebrovascular disease.
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Cited by
Baijens, L. W., Clavé, P., Cras, P., Ekberg, O., Forster, A., Kolb, G., Leners, J. C., Masiero, S., Mateos del Nozal, J., Ortega, O., et al. (2016) · Clinical Interventions in Aging · doi:10.2147/cia.s107750 · Cited by 773
Diagnosis and Management of Oropharyngeal Dysphagia Among Older Persons, State of the Art
Ortega, O., Martín, A., & Clavé, P. (2017) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2017.02.015 · Cited by 283
Oral-lung microbiome interactions in lung diseases.
Mammen, M. J., Scannapieco, F. A., & Sethi, S. (2020) · Periodontology 2000 · doi:10.1111/prd.12301 · Cited by 179
Naruishi, K., Kunita, A., Kubo, K., Nagata, T., Takashiba, S., & Adachi, S. (2014) · Clinical Interventions in Aging · doi:10.2147/cia.s73388 · Cited by 20
Kritas, S., Dejaeger, E., Tack, J., Omari, T., & Rommel, N. (2016) · Neurogastroenterology & Motility · doi:10.1111/nmo.12730 · Cited by 18
Metadata
- Authors
- van der Maarel-Wierink, C. D., Vanobbergen, J. N. O., Bronkhorst, E. M., Schols, J. M. G. A., & de Baat, C.
- Venue
- Journal of Dental Research
- Publisher
- SAGE Publications
- Published
- 2011-09-22
- Volume
- 90
- Issue
- 12
- Pages
- 1398-1404
- ISSN
- 0022-0345 (ISSN-L)
- 1544-0591
- OpenAlex
- W2158889217
- Cited by
- 186
- References
- 0
- FWCI
- 2.11
- Type
- journal article
- Language
- en
- Open access
- closed
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- van der Maarel-Wierink, C. D., Vanobbergen, J. N. O., Bronkhorst, E. M., Schols, J. M. G. A., & de Baat, C. (2011). Meta-analysis of Dysphagia and Aspiration Pneumonia in Frail Elders. Journal of Dental Research. https://doi.org/10.1177/0022034511422909
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