The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
Osteoinduction: A Review of Old Concepts with New Standards
Abstract
Since the discovery of osteoinduction in the early 20th century, innovative biomaterials with osteoinductive potential have emerged. Over the last 50 years, however, our ability to describe biological phenomena accurately has been improved dramatically by advancements in cell and molecular biology. The aim of this review is to divide the osteoinduction phenomenon into 3 principles: (1) mesenchymal cell recruitment, (2) mesenchymal differentiation to bone-forming osteoblasts, and (3) ectopic bone formation in vivo. Furthermore, this review formulates guidelines for in vitro and in vivo experimental testing for accurately defining new biomaterials as osteoinductive. The use of growth factors with osteoinductive potential in periodontal and oral surgery is discussed. These concepts and guidelines aim to guide the future direction of emerging biomaterials in bone regeneration.
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Cites
Bone: Formation by Autoinduction
Urist, M. R. (1965) · Science · doi:10.1126/science.150.3698.893 · Cited by 5,546
Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation
Ducy, P., Zhang, R., Geoffroy, V., Ridall, A. L., & Karsenty, G. (1997) · Cell · doi:10.1016/s0092-8674(00)80257-3 · Cited by 4,246
Nakashima, K., Zhou, X., Kunkel, G., Zhang, Z., Deng, J. M., Behringer, R. R., & de Crombrugghe, B. (2002) · Cell · doi:10.1016/s0092-8674(01)00622-5 · Cited by 3,608
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
Méndez-Ferrer, S., Michurina, T. V., Ferraro, F., Mazloom, A. R., MacArthur, B. D., Lira, S. A., Scadden, D. T., Ma’ayan, A., Enikolopov, G. N., & Frenette, P. S. (2010) · Nature · doi:10.1038/nature09262 · Cited by 3,374
Szer, J. (1999) · Medical Journal of Australia · doi:10.5694/j.1326-5377.1999.tb127745.x · Cited by 3,353
MAPK signal pathways in the regulation of cell proliferation in mammalian cells
ZHANG, W., & LIU, H. T. (2002) · Cell Research · doi:10.1038/sj.cr.7290105 · Cited by 2,845
Friedenstein, A. J., Chailakhjan, R. K., & Lalykina, K. S. (1970) · Cell Proliferation · doi:10.1111/j.1365-2184.1970.tb00347.x · Cited by 2,724
Giannoudis, P. V., Dinopoulos, H., & Tsiridis, E. (2005) · Injury · doi:10.1016/j.injury.2005.07.029 · Cited by 2,078
Horwitz, E. M., Le Blanc, K., Dominici, M., Mueller, I., Slaper-Cortenbach, I., Marini, F. C., Deans, R. J., Krause, D. S., & Keating, A. (2005) · Cytotherapy · doi:10.1080/14653240500319234 · Cited by 2,073
Phinney, D. G., & Prockop, D. J. (2007) · Stem Cells · doi:10.1634/stemcells.2007-0637 · Cited by 1,908
Cited by
Humbert, P., Brennan, M. Á., Davison, N., Rosset, P., Trichet, V., Blanchard, F., & Layrolle, P. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00663 · Cited by 119
Osteoinductive micro-nano guided bone regeneration membrane for in situ bone defect repair
Wang, B., Xie, X., Jiang, W., Zhan, Y., Zhang, Y., Guo, Y., Wang, Z., Guo, N., Guo, K., & Sun, J. (2024) · Stem Cell Research & Therapy · doi:10.1186/s13287-024-03745-w · Cited by 27
Self-citation
Metadata
- Authors
- Miron, R. J., & Zhang, Y. F.
- Venue
- Journal of Dental Research
- Publisher
- SAGE Publications
- Published
- 2012-02-08
- Volume
- 91
- Issue
- 8
- Pages
- 736-744
- ISSN
- 0022-0345 (ISSN-L)
- 1544-0591
- OpenAlex
- W2115327066
- Cited by
- 334
- References
- 74
- FWCI
- 11.68
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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