Impact of Patient Compliance on Tooth Loss during Supportive Periodontal Therapy: A Systematic Review and Meta-analysis

Lee, C.T.; Huang, H.Y.; Sun, T.C.; Karimbux, N.

doi:10.1177/0022034515578910

Cited by 128Oral microbiology and periodontitis researchDental Health and Care UtilizationPeriodontal Regeneration and Treatments

Impact of Patient Compliance on Tooth Loss during Supportive Periodontal Therapy: A Systematic Review and Meta-analysis

Lee, C.T., Huang, H.Y., Sun, T.C., Karimbux, N.·2015·Journal of Dental Research

DOI 10.1177/0022034515578910

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Abstract

Periodontal treatment consists of active periodontal therapy (APT) and supportive periodontal therapy (SPT). Regular SPT is recommended to prevent and control the occurrence of periodontal disease following APT. A patient’s compliance with SPT is considered one of the most important factors affecting long-term periodontal status. Tooth loss is generally considered the final outcome of periodontitis. This review aimed to analyze the relationship between patient compliance with regular SPT and tooth loss. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guideline for systematic reviews was used. A search of articles was conducted using MEDLINE (PubMed) and other databases. Quality assessments of selected studies were performed. To assess the effect of compliance on tooth loss during SPT, pooled risk ratio of tooth loss (RRTL) was used as the primary outcome. Pooled risk difference of tooth loss (RDTL) and weighted mean difference of tooth loss rate (WDTLR) were used as secondary outcomes. Subgroup analysis and meta-regression were conducted to evaluate the effects of different variables. In total, 710 articles were screened. Eight studies, which had a regular-compliance (RC) group and an erratic-compliance (EC) group with at least a 5-y follow-up period, qualified for the meta-analysis. The risk of tooth loss in the RC group was significantly lower than that in the EC group (pooled RRTL: 0.56 [confidence interval (CI): 0.38, 0.82]; pooled RDTL: –0.05 [CI: –0.08, –0.01]). The definition of compliance was a variable significantly related to risk ratio of tooth loss. Patients in the RC group had significantly lower tooth loss rate during SPT than did patients in the EC group (WDTLR: –0.12 [CI: –0.19, –0.05]). Teeth have less risk of being lost if patients are more compliant with supportive periodontal therapy. However, unidentified variables causing data heterogeneity and affecting the risk of tooth loss may have been present. More well-controlled prospective studies are needed in the future.

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Despite lack of consistency among studies in type and frequency of instruction and motivation, higher compliance encourages improvement in clinical outcomes.
“and despite the lack of consistency among studies in terms of type and frequency of instruction and motivation, higher compliance encourages the improvement in clinical outcomes [42–45].”
From Concordance and Clinical Outcomes Improvement Following Oral Hygiene Motivation: A Systematic Review and Report of the Workshop of the Italian Societies of Dental Hygiene (2024) · cites this paper as [42]

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Authors: Lee, C. T., Huang, H. Y., Sun, T. C., & Karimbux, N.
Affiliations: Harvard University (US)
School of Dentistry, National Defense Medical Center, Taipei, Taiwan
Tufts University (US)
Venue: Journal of Dental Research
Publisher: SAGE Publications
Published: 2015-03-27
Volume: 94
Issue: 6
Pages: 777-786
ISSN: 0022-0345 (ISSN-L)
1544-0591
DOI: 10.1177/0022034515578910
OpenAlex: W2143583164
Cited by: 128
References: 58
Citations by year: 2026: 9 · 2025: 8 · 2024: 14 · 2023: 6 · 2022: 7 · 2021: 18 · 2020: 18 · 2019: 14 · 2018: 14 · 2017: 9 · 2016: 9 · 2015: 2
FWCI: 1.95
Type: journal article
Language: en
Open access: closed
Licence: journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: Journal of Dental Research (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
Health Sciences › Dentistry › Periodontics › Dental Health and Care Utilization
Health Sciences › Medicine › Urology › Periodontal Regeneration and Treatments
Keywords: medication adherence, periodontal maintenance, tooth loss, periodontitis
MeSH terms: Follow-Up Studies, Humans, Patient Compliance, Periodontal Diseases, Periodontal Index, Risk Factors, Tooth Loss

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Impact of Patient Compliance on Tooth Loss during Supportive Periodontal Therapy: A Systematic Review and Meta-analysis

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