Personality Characteristics of Volunteers for Medical Research
Abstract
Thirty-seven inmates who had previously volunteered for phase I drug testing and 33 who had not were interviewed by a psychologist to obtain demographic and motivational data. Each inmate completed a standard psychopathology inventory (the Minnesota Multiphasic Personality Inventory), the Similarities and Picture Arrangement subtests of the Wechsler Adult Intelligence Scale, a test of normal personality variables (the Edwards Personality Scale), and Christie's Machiavellianism Scale. The data supported the conclusions that (1) inmates are in general free enough from psychopathology to be able to make rational choices about participating in medical research as long as preliminary screening for individuals with severely disordered thinking is carried out, (2) verbal communication skills of inmates appear to be well enough developed to allow them to give an informed consent, (3) while there are personality differences between volunteers and nonvolunteers, these appear to relate most directly to the fact that, without screening, impulsive, manipulative individuals with disordered thought processes are over-represented among volunteers for medical research.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Volunteer bias is the tendency for well-adjusted, open, and compliant people to participate in studies, a function of personality.
“For instance, volunteer bias, a form of selection bias, is the tendency for well-adjusted, open, and compliant people to participate in studies [261], a function of personality [263, 264].”
From Personality and Longevity: Knowns, Unknowns, and Implications for Public Health and Personalized Medicine (2011) · cites this paper as [263]
Cites
The Measurement and Appraisal of Adult Intelligence
Webster, A. S., & Wechsler, D. (1958) · The Journal of Criminal Law Criminology and Police Science · doi:10.2307/1141601 · Cited by 1,812 · see citing works
The Measurement and Appraisal of Adult Intelligence (4th ed.).
Wechsler, D. (1958) · doi:10.1037/11167-000 · Cited by 1,683 · see citing works
Ch, A. (2008) · Encyclopedia of Special Education · doi:10.1002/9780470373699.speced1566 · Cited by 364 · see citing works
Christie, R. (1970) · Elsevier eBooks · doi:10.1016/b978-0-12-174450-2.50006-3 · Cited by 320 · see citing works
Personality Dimensions in Delinquent Males as Inferred from the Factor Analysis of Behavior Ratings
Quay, H. C. (1964) · Journal of Research in Crime and Delinquency · doi:10.1177/002242786400100104 · Cited by 130 · see citing works
The Journal of Clinical Pharmacology
(2022) · The Journal of Clinical Pharmacology · doi:10.1002/(issn)1552-4604 · Cited by 98 · see citing works
Motivations and rewards for volunteering to be an experimental subject
Ayd, F. J. (1972) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt1972135part2771 · Cited by 29 · see citing works
A Psychosocial Description of Penitentiary Inmates
Sutker, P. B. (1973) · Archives of General Psychiatry · doi:10.1001/archpsyc.1973.04200050070012 · Cited by 24 · see citing works
Research with the Wechsler Intelligence Scales for Adults: 1965–1970
Guertin, W. H., Ladd, C. E., Frank, G., et al. (1971) · The Psychological Record · doi:10.1007/bf03394023 · Cited by 24 · see citing works
The Use of Prisoners for Medical Research
Hodges, R. E. (1967) · JAMA · doi:10.1001/jama.1967.03130190119018 · Cited by 13 · see citing works
Why Prisoners Volunteer to Be Experimental Subjects
McDonald, J. C. (1967) · JAMA · doi:10.1001/jama.1967.03130190117017 · Cited by 10 · see citing works
Personality Factors in Prison Volunteers Related to Response in Clinical Drug Trials
WEISSMAN, L., Moore, J. D., Thomas, G., et al. (1972) · The Journal of Clinical Pharmacology · doi:10.1002/j.1552-4604.1972.tb00029.x · Cited by 7 · see citing works
Personality Characteristics of Volunteer Subjects
Neulinger, J., & Stein, M. I. (1971) · Perceptual and Motor Skills · doi:10.2466/pms.1971.32.1.283 · Cited by 5 · see citing works
Guidelines for accepting volunteers: Consent, ethical implications, and the fundion of a peer review
Morris, R. C. (1972) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt1972135part2782 · Cited by 5 · see citing works
Patient Consent—What Makes it Informed?
Benson, H., Barry, M., & Place, V. A. (1975) · Drug Information Journal · doi:10.1177/009286157500900110 · Cited by 3 · see citing works
Problems in the Evaluation of a New Antidepressant Drug in Prison Volunteers
Blackwell, B., & Ayd, F. J. (1971) · The Journal of Clinical Pharmacology · doi:10.1177/009127007101100103 · Cited by 3 · see citing works
American Correctional Association
Hanser, R. D. (2013) · The Encyclopedia of Criminology and Criminal Justice · doi:10.1002/9781118517383.wbeccj106 · Cited by 2 · see citing works
Carr, E. A. (1972) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt1972135part2790 · Cited by 2 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Chapman, B. P., Roberts, B., & Duberstein, P. (2011) · Journal of Aging Research · doi:10.4061/2011/759170 · Cited by 283 · see citing works
“For instance, volunteer bias, a form of selection bias, is the tendency for well-adjusted, open, and compliant people to participate in studies [261], a function of personality [263, 264].”
Background
- Authors
- Walsh, J. A., & Nash, M. M.
- Affiliations
- University of Montana (US)
- Montana State Prison
- ORCID
- Walsh, James A.
- Venue
- Correctional Psychologist
- Publisher
- SAGE Publications
- Published
- 1978-06
- Volume
- 5
- Issue
- 2
- Pages
- 99-116
- ISSN
- 0589-8218 (ISSN-L)
- OpenAlex
- W1973415835
- Cited by
- 13
- References
- 18
- Citations by year
- 2024: 1 · 2019: 1 · 2018: 1 · 2017: 3
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Correctional Psychologist (publishedVersion)
- PubMed (publishedVersion)
- DigitalGeorgetown (Georgetown University Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
- Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
- Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
- Keywords
- research volunteers, personality traits, psychopathology, informed consent, verbal communication skills, Machiavellianism, impulsivity
- MeSH terms
- Evaluation Studies as Topic, Humans, Human Experimentation, Informed Consent, Motivation, Personality, Prisoners, Volunteers
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review