The DOI matches its Crossref record.
Effect of Endoscopic Sinus Surgery on Pulmonary Status of Adults with Cystic Fibrosis
Abstract
Objective Functional endoscopic sinus surgery (FESS) provides symptomatic relief of sinus disease in patients with cystic fibrosis (CF), but it is unclear whether it has beneficial effects on lung disease in this population. This study assessed the effect of FESS on the respiratory status of adult patients with CF. Study design Retrospective chart review. Setting Tertiary medical center. Subjects Thirty-two adult patients with CF who underwent 45 operative cases. Methods Clinical information retrieved for the 12-month periods preceding and following to determine the effect of FESS on the rate of decline in lung function, as well as intravenous antibiotic use and hospitalization for pulmonary exacerbation. Results The rate of decline in forced expiratory volume in 1 second and forced vital capacity was not significantly different in the 12 months before and after FESS. Functional endoscopic sinus surgery did not reduce days hospitalized or days on intravenous antibiotics for a respiratory exacerbation in the pre- vs postoperative period. Limiting the analysis to the 30 surgeries that were performed in patients with concomitant respiratory symptoms (ie, excluding the 15 surgeries performed for sinus symptoms alone) did not significantly alter the results. Covariates of importance in CF, including CFTR genotype, gender, or microbiology, did not affect the study results. Conclusion These results did not demonstrate an effect of FESS on progression of lung disease in patients with…
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Surgery may be beneficial in patients with nasal polyps with associated asthma, aspirin-exacerbated respiratory disease, or cystic fibrosis.
“Surgery may be beneficial in patients with NP with associated asthma [228,229], AERD [230], or cystic fibrosis [231-233].”
From Position Paper on Nasal Obstruction: Evaluation and Treatment (2018) · cites this paper as [232]
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Research works printed but not linked: 18
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- Pylkas A, 2007, Effect of functional endoscopic sinus surgery on the respiratory status of adults with cystic fibrosis, Pediatr Pulmonol, 42, A411
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Cited by
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Position Paper on Nasal Obstruction: Evaluation and Treatment
SEAIC Rhinoconjunctivitis Committee & SEORL Rhinology, A., Valero, A., Navarro, A., del Cuvillo, A., Alobid, I., Benito, Jr., Colás, C., de los Santos, G., Fernández Liesa, R., García-Lliberós, A., et al. (2018) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0232 · Cited by 76
Metadata
- Authors
- Kempainen, R. R., Sajan, J. A., Pylkas, A. M., Dunitz, J. M., Rimell, F. L., & Milla, C. E.
- Affiliations
- University of Minnesota (US)
- Stanford Medicine (US)
- Corresponding author
- Sajan, Javad A.
- Venue
- Otolaryngology–Head and Neck Surgery
- Publisher
- Wiley
- Published
- 2012-04-18
- Volume
- 147
- Issue
- 3
- Pages
- 557-562
- ISSN
- 0161-6439 (ISSN-L)
- 0194-5998
- 1097-6817
- OpenAlex
- W2135549347
- Cited by
- 23
- References
- 0
- Citations by year
- 2023: 1 · 2022: 2 · 2021: 4 · 2020: 4 · 2019: 1 · 2018: 1 · 2017: 2 · 2014: 1 · 2013: 3 · 2012: 4
- FWCI
- 2.06
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Otolaryngology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
- Health Sciences › Medicine › Otorhinolaryngology › Sinusitis and nasal conditions
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- functional endoscopic sinus surgery, cystic fibrosis, lung function decline, pulmonary exacerbations, intravenous antibiotics, hospitalization, sinus disease, adults with cystic fibrosis
- MeSH terms
- Adult, Cystic Fibrosis, Endoscopy, Female, Forced Expiratory Volume, Humans, Longitudinal Studies, Male, Paranasal Sinuses, Postoperative Complications, Spirometry, Vital Capacity, Young Adult
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