Cited by 166Cancer survivorship and carePalliative and Oncologic CarePalliative Care and End-of-Life Issues

The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.

Managing Cancer And Living Meaningfully (CALM): Phase 2 trial of a brief individual psychotherapy for patients with advanced cancer

Open access
Lo, Chris, Hales, Sarah, Jung, Judy, Chiu, Aubrey, Panday, Tania, Rydall, Anne, Nissim, Rinat, Malfitano, Carmine, Petricone-Westwood, Danielle, Zimmermann, Camilla, Rodin, Gary·2014·Palliative Medicine

Abstract

Background: Advanced cancer brings substantial physical and psychosocial challenges that may contribute to emotional distress and diminish well-being. In this study, we present preliminary data concerning the effectiveness of a new brief individual psychotherapy, Managing Cancer And Living Meaningfully (CALM), designed to help individuals cope with this circumstance. Aim: To test the feasibility and preliminary effectiveness of CALM to reduce emotional distress and promote psychological well-being and growth. Design: CALM is a brief, manualized, semi-structured individual psychotherapy for patients with advanced cancer. This study employed a phase 2 intervention-only design. The primary outcome was depressive symptoms and the secondary outcomes were death anxiety, attachment security, spiritual well-being and psychological growth. These were assessed at 3 months (t1) and 6 months (t2). Multilevel regression was used to model change over time. Setting/participants: A total of 50 patients with advanced or metastatic cancer were recruited from the Princess Margaret Cancer Centre, Toronto, Canada. Results: A total of 39 patients (78%) were assessed at baseline, 24 (48%) at t1, and 16 (32%) at t2. Analyses revealed reductions over time in depressive symptoms: beta = −0.13, confidence interval (CI .95 ) = (−0.23, −0.022) and death anxiety: beta = −0.23, CI .95 (−0.40, −0.061); and an increase in spiritual well-being: beta = 0.14, CI .95 (0.026, 0.26). Conclusions: CALM may be a feasible intervention to benefit patients with advanced cancer. The results are encouraging, despite attrition and small effect sizes, and support further study.

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Research works printed but not linked: 4

  1. Akechi T, 2008, Cochrane Database Syst Rev, 2, CD005537
  2. Bowlby J, 1982, Attachment
  3. 10.3102/10769986023004323 · DOI · Paper page
  4. 10.1037/0033-2909.112.1.155 · DOI · Paper page

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Metadata

Authors
Lo, C., Hales, S., Jung, J., Chiu, A., Panday, T., Rydall, A., Nissim, R., Malfitano, C., Petricone-Westwood, D., Zimmermann, C., & Rodin, G.
Affiliations
  • Department of Psychosocial Oncology and Palliative Care, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
  • University Health Network (CA)
Venue
Palliative Medicine
Published
2013-10-29
Volume
28
Issue
3
Pages
234-242
ISSN
  • 0269-2163 (ISSN-L)
  • 1477-030X
OpenAlex
W2159372318
Cited by
166
References
56
Citations by year
2026: 11 · 2025: 12 · 2024: 5 · 2023: 14 · 2022: 18 · 2021: 12 · 2020: 14 · 2019: 13 · 2018: 18 · 2017: 20 · 2016: 11 · 2015: 14 · 2014: 4
FWCI
5.17
Type
journal article
Language
en
Open access
Locations
  • Palliative Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • TSpace (University of Toronto) (submittedVersion, public-domain)
Funders
  • Cancer Research Institute
  • Princess Margaret Cancer Foundation
  • University of Toronto
  • Canadian Institutes of Health Research (MOP106473)
Topics
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
Keywords
advanced cancer, metastatic cancer, depressive symptoms, fear of death, spiritual well-being, psychological growth, attachment security, emotional distress, psychological well-being, feasibility
MeSH terms
Attitude to Death, Depressive Disorder, Feasibility Studies, Female, Humans, Interpersonal Relations, Male, Middle Aged, Neoplasms, Palliative Care, Pilot Projects, Psychotherapy, Brief, Regression Analysis, Stress, Psychological, Qualitative Research

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