Estimating Costs of an Implementation Intervention
Abstract
Health care systems frequently have to decide whether to implement interventions designed to reduce gaps in the quality of care. A lack of information on the cost of these interventions is often cited as a barrier to implementation. In this article, we describe methods for estimating the cost of implementing a complex intervention. We review methods related to the direct measurement of labor, supplies and space, information technology, and research costs. We also discuss several issues that affect cost estimates in implementation studies, including factor prices, fidelity, efficiency and scale of production, distribution, and sunk costs. We examine case studies for stroke and depression, where evidence-based treatments exist and yet gaps in the quality of care remain. Understanding the costs for implementing strategies to reduce these gaps and measuring them consistently will better inform decision makers about an intervention’s likely effect on their budget and the expected costs to implement new interventions.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The review did not include implementation costs as an outcome because reporting guidelines have not been standardized.
“Further, we did not include implementation costs as an outcome because reporting guidelines have not been standardized [38, 39].”
From A systematic review of experimentally tested implementation strategies across health and human service settings: evidence from 2010-2022 (2024) · cites this paper as [38]
There has been a recent surge of publications related to the collection of costs in implementation science, and emerging consensus regarding the importance of economic influences on implementation outcomes.
“There has been a recent surge of publications related to the collection of costs in implementation science [9, 14, 31, 36], and emerging consensus regarding the importance of economic influences on implementation outcomes (see other articles in this collection).”
From Implementation science issues in understanding, collecting, and using cost estimates: A multi-stakeholder perspective (2021) · cites this paper as [14]
Cites
The Economic Implications of Learning by Doing
Arrow, K. J. (1962) · The Review of Economic Studies · doi:10.2307/2295952 · Cited by 7,202 · see citing works
Cost-Effectiveness in Health and Medicine
(1996) · doi:10.1093/oso/9780195108248.001.0001 · Cited by 7,193 · see citing works
Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke
Hacke, W., Kaste, M., Bluhmki, E., Brozman, M., Dávalos, A., Guidetti, D., Larrue, V., Lees, K. R., Medeghri, Z., Machnig, T., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0804656 · Cited by 6,684 · see citing works
Audit and feedback: effects on professional practice and healthcare outcomes
Ivers, N., Jamtvedt, G., Flottorp, S., Young, J. M., Odgaard-Jensen, J., French, S. D., O'Brien, M. A., Johansen, M., Grimshaw, J., & Oxman, A. D. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000259.pub3 · Cited by 5,485 · cited 1× · see citing works
“An example would be showing a provider how they perform relative to their peers on an electronic dashboard as a form of audit and feedback.(22) Sometimes off-the-shelf products are available for purchase, and other times, the technology needs to be made de novo.”
BackgroundPowell, B. J., Waltz, T. J., Chinman, M. J., Damschroder, L. J., Smith, J. L., Matthieu, M. M., Proctor, E. K., & Kirchner, J. E. (2015) · Implementation Science · doi:10.1186/s13012-015-0209-1 · Cited by 4,963 · see citing works
Methods for the economic evaluation of health care programmes
Wilson, S. (1987) · Journal of Epidemiology & Community Health · doi:10.1136/jech.41.4.355-a · Cited by 4,312 · see citing works
Effectiveness and efficiency of guideline dissemination and implementation strategies
Grimshaw, J., Thomas, R., MacLennan, G., Fraser, C., Ramsay, C., Vale, L., Whitty, P., Eccles, M., Matowe, L., Shirran, L., et al. (2004) · Health Technology Assessment · doi:10.3310/hta8060 · Cited by 3,044 · see citing works
Implementation strategies: recommendations for specifying and reporting
Proctor, E. K., Powell, B. J., & McMillen, J. C. (2013) · Implementation Science · doi:10.1186/1748-5908-8-139 · Cited by 2,585 · see citing works
Cost-Effectiveness in Health and Medicine
(2016) · doi:10.1093/acprof:oso/9780190492939.001.0001 · Cited by 1,552 · see citing works
Wicked Problems, Knowledge Challenges, and Collaborative Capacity Builders in Network Settings
Weber, E. P., & Khademian, A. M. (2008) · Public Administration Review · doi:10.1111/j.1540-6210.2007.00866.x · Cited by 1,186 · see citing works
Collaborative care for depression and anxiety problems
Archer, J., Bower, P., Gilbody, S., Lovell, K., Richards, D., Gask, L., Dickens, C., & Coventry, P. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006525.pub2 · Cited by 1,126 · see citing works
Stinnett, A. A., & Mullahy, J. (1998) · Medical Decision Making · doi:10.1177/0272989x98018002s09 · Cited by 1,103 · see citing works
Sullivan, S., Mauskopf, J., Augustovski, F., Caro, J., Lee, K. M., Minchin, M., Orlewska, E., Penna, P., Barrios, J. R. R., & Shau, W. (2014) · Value in Health · doi:10.1016/j.jval.2013.08.2291 · Cited by 1,069 · see citing works
Methods to Improve the Selection and Tailoring of Implementation Strategies
Powell, B. J., Beidas, R. S., Lewis, C. C., Aarons, G. A., McMillen, J. C., Proctor, E. K., & Mandell, D. S. (2017) · The Journal of Behavioral Health Services & Research · doi:10.1007/s11414-015-9475-6 · Cited by 967 · see citing works
Economic foundations of cost-effectiveness analysis
Garber, A. M., & Phelps, C. E. (1997) · Journal of Health Economics · doi:10.1016/s0167-6296(96)00506-1 · Cited by 768 · see citing works
Review of statistical methods for analysing healthcare resources and costs
Mihaylova, B., Briggs, A., O'Hagan, A., & Thompson, S. G. (2011) · Health Economics · doi:10.1002/hec.1653 · Cited by 767 · see citing works
Mauskopf, J., Sullivan, S. D., Annemans, L., Jaime, J., Mullins, C. D., Nuijten, M. J. C., Orlewska, E., Watkins, J., & Trueman, P. (2007) · Value in Health · doi:10.1111/j.1524-4733.2007.00187.x · Cited by 752 · see citing works
Hoch, J. S., Briggs, A. H., & Willan, A. R. (2002) · Health Economics · doi:10.1002/hec.678 · Cited by 535 · see citing works
Programme costs in the economic evaluation of health interventions
Johns, B., Baltussen, R., & Hutubessy, R. (2003) · Cost Effectiveness and Resource Allocation · doi:10.1186/1478-7547-1-1 · Cited by 329 · see citing works
Microcosting Quantity Data Collection Methods
Frick, K. D. (2009) · Medical Care · doi:10.1097/mlr.0b013e31819bc064 · Cited by 294 · see citing works
Promoting intervention fidelity
Dumas, J. E., Lynch, A. M., Laughlin, J. E., Smith, E. P., & Prinz, R. J. (2001) · American Journal of Preventive Medicine · doi:10.1016/s0749-3797(00)00272-5 · Cited by 277 · see citing works
Estimating Costs in Cost Effectiveness Analysis
Luce, B. R., Manning, W. G., Siegel, J. E., & Lipscomb, J. (1996) · doi:10.1093/oso/9780195108248.003.0006 · Cited by 229 · see citing works
A Solution-Focused Research Approach to Achieve an Implementable Revolution in Digital Mental Health
Mohr, D. C., Riper, H., & Schueller, S. M. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.3838 · Cited by 204 · cited 1× · see citing works
“costs may change over time, especially if there is variation in how the intervention was implemented as planned.(39) In these cases, it may be useful to collect data on fidelity at multiple phases of the implementation process.”
BackgroundSystematic, Multimethod Assessment of Adaptations Across Four Diverse Health Systems Interventions
Rabin, B. A., McCreight, M., Battaglia, C., Ayele, R., Burke, R. E., Hess, P. L., Frank, J. W., & Glasgow, R. E. (2018) · Frontiers in Public Health · doi:10.3389/fpubh.2018.00102 · Cited by 147 · see citing works
Shortell, S. M. (2004) · Medical Care Research and Review · doi:10.1177/1077558704266768 · Cited by 145 · see citing works
Mixed-method approaches to strengthen economic evaluations in implementation research
Dopp, A. R., Mundey, P., Beasley, L. O., Silovsky, J. F., & Eisenberg, D. (2019) · Implementation Science · doi:10.1186/s13012-018-0850-6 · Cited by 118 · see citing works
Using Average Cost Methods to Estimate Encounter-Level Costs for Medical-Surgical Stays in the VA
Wagner, T. H., Chen, S., & Barnett, P. G. (2003) · Medical Care Research and Review · doi:10.1177/1077558703256485 · Cited by 103 · see citing works
Self-citationStandards of Evidence for Conducting and Reporting Economic Evaluations in Prevention Science
Crowley, D. M., Dodge, K. A., Barnett, W. S., Corso, P. S., Duffy, S. Q., Graham, P., Greenberg, M. H., Haskins, R., Hill, L. G., Jones, D. E., et al. (2018) · Prevention Science · doi:10.1007/s11121-017-0858-1 · Cited by 92 · see citing works
Paul, C. L., Ryan, A., Rose, S., Attia, J., Kerr, E. M., Koller, C. E., & Levi, C. R. (2015) · Implementation Science · doi:10.1186/s13012-016-0414-6 · Cited by 78 · see citing works
Budget impact analysis in economic evaluation: a proposal for a clearer definition
Garattini, L., & van de Vooren, K. (2011) · The European Journal of Health Economics · doi:10.1007/s10198-011-0348-5 · Cited by 74 · see citing works
Estimating the Costs of VA Ambulatory Care
Phibbs, C. S., Bhandari, A., Yu, W., & Barnett, P. G. (2003) · Medical Care Research and Review · doi:10.1177/1077558703256725 · Cited by 69 · see citing works
Self-citationThe costs of screening and brief intervention for risky alcohol use.
Zarkin, G. A., Bray, J. W., Davis, K. L., Babor, T. F., & Higgins-Biddle, J. C. (2003) · Journal of Studies on Alcohol · doi:10.15288/jsa.2003.64.849 · Cited by 64 · see citing works
Øvretveit, J., Leviton, L. C., & Parry, G. J. (2011) · BMJ Quality & Safety · doi:10.1136/bmjqs.2010.046342 · Cited by 56 · see citing works
Estimating Costs and Valuations of Non-Health Benefits in Cost-Effectiveness Analysis
Basu, A. (2016) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780190492939.003.0008 · Cited by 43 · see citing works
Assigning Resources to Health Care Use for Health Services Research
Fishman, P. A., & Hornbrook, M. C. (2009) · Medical Care · doi:10.1097/mlr.0b013e3181a75a7f · Cited by 37 · see citing works
Claes, N., Moeremans, K., Buntinx, F., Jef, A., Jos, V., Herman, V. L., & Lieven, A. (2006) · Value in Health · doi:10.1111/j.1524-4733.2006.00129.x · Cited by 35 · see citing works
Hoeft, T. J., Wilcox, H., Hinton, L., & Unützer, J. (2019) · Implementation Science · doi:10.1186/s13012-019-0882-6 · Cited by 34 · see citing works
McGrew, J. H., White, L. M., Stull, L. G., & Wright-Berryman, J. (2013) · Psychiatric Services · doi:10.1176/appi.ps.001252012 · Cited by 20 · see citing works
Estimating Downstream Budget Impacts in Implementation Research
Wagner, T. H., Dopp, A. R., & Gold, H. T. (2020) · Medical Decision Making · doi:10.1177/0272989x20954387 · Cited by 20 · see citing works
Self-citationCost-effectiveness of supported employment for veterans with spinal cord injuries
Sinnott, P. L., Joyce, V., Su, P., Ottomanelli, L., Goetz, L. L., & Wagner, T. H. (2014) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2014.01.010 · Cited by 19 · see citing works
Self-citationHasche, L. K., Lenze, S. N., Brown, T., Lawrence, L., Nickel, M., Morrow-Howell, N. L., & Proctor, E. K. (2013) · Administration and Policy in Mental Health and Mental Health Services Research · doi:10.1007/s10488-013-0519-z · Cited by 17 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Reflections on 10 years of effectiveness-implementation hybrid studies
Curran, G. M., Landes, S. J., McBain, S. A., Pyne, J. M., Smith, J. D., Fernandez, M. E., Chambers, D. A., & Mittman, B. S. (2022) · Frontiers in Health Services · doi:10.3389/frhs.2022.1053496 · Cited by 299 · see citing works
Cost data in implementation science: categories and approaches to costing
Gold, H. T., McDermott, C., Hoomans, T., & Wagner, T. H. (2022) · Implementation Science · doi:10.1186/s13012-021-01172-6 · Cited by 152 · see citing works
Self-citationEisman, A. B., Quanbeck, A., Bounthavong, M., Panattoni, L., & Glasgow, R. E. (2021) · Implementation Science · doi:10.1186/s13012-021-01143-x · Cited by 126 · see citing works
Ashcraft, L. E., Goodrich, D. E., Hero, J., Phares, A., Bachrach, R. L., Quinn, D. A., Qureshi, N., Ernecoff, N. C., Lederer, L. G., Scheunemann, L. P., et al. (2024) · Implementation Science · doi:10.1186/s13012-024-01369-5 · Cited by 89 · see citing works
Self-citation
- Authors
- Wagner, T. H., Yoon, J., Jacobs, J. C., So, A., Kilbourne, A. M., Yu, W., & Goodrich, D. E.
- Affiliations
- VA Palo Alto Health Care System (US)
- United States Department of Veterans Affairs (US)
- Corresponding author
- Wagner, Todd H.
- Venue
- Medical Decision Making
- Publisher
- SAGE Publications
- Published
- 2020-10-20
- Volume
- 40
- Issue
- 8
- Pages
- 959-967
- ISSN
- 0272-989X (ISSN-L)
- 1552-681X
- OpenAlex
- W3092759154
- Cited by
- 59
- References
- 41
- Citations by year
- 2026: 3 · 2025: 12 · 2024: 17 · 2023: 11 · 2022: 14 · 2021: 2
- FWCI
- 7.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Medical Decision Making (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Funders
- u.s. department of veterans affairs
- Topics
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
- Keywords
- implementation costs, complex interventions, cost estimation, evidence-based treatment, stroke care, depression treatment, factor prices, fidelity, production scale, sunk costs, information technology costs, health care budgeting
- MeSH terms
- Implementation Science, Cost-Benefit Analysis, Humans, Statistics as Topic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review