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Cited by 871

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Autologous Chondrocyte Transplantation: Biomechanics and Long-Term Durability

Peterson, Lars, Brittberg, Mats, Kiviranta, Illka, Åkerlund, Evy Lundgren, Lindahl, Anders·2002·The American Journal of Sports Medicine

Abstract

We evaluated the durability of autologous chondrocyte transplantation grafts in 61 patients treated for isolated cartilage defects on the femoral condyle or the patella and followed up for a mean of 7.4 years (range, 5 to 11). Durability was determined by comparing the clinical status at the long-term follow-up with that found 2 years after the transplantation. After 2 years, 50 of the 61 patients had good or excellent clinical results, and 51 of 61 had good or excellent results at 5 to 11 years later. Grafted areas from 11 of the patients were evaluated with an electromechanical indentation probe during a second-look arthroscopy procedure (mean follow-up, 54.3 months; range, 33 to 84); stiffness measurements were 90% or more of those of normal cartilage in eight patients. Eight of twelve 2-mm biopsy samples taken from these patients showed hyaline characteristics with safranin O staining and a homogeneous appearance in polarized light. Three fibrous and eight hyaline biopsy specimens stained positive to aggrecan and to cartilage oligomeric matrix protein. Hyaline-like specimens stained positive for type II collagen, and fibrous, for type I collagen. Autologous chondrocyte transplantation for the treatment of articular cartilage injuries has a durable outcome for as long as 11 years.

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Metadata

Authors
Peterson, L., Brittberg, M., Kiviranta, I., Åkerlund, E. L., & Lindahl, A.
Venue
The American Journal of Sports Medicine
Published
2002-01
Volume
30
Issue
1
Pages
2-12
ISSN
  • 0363-5465 (ISSN-L)
  • 1552-3365
OpenAlex
W2026458998
Cited by
871
References
18
FWCI
24.91
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Autologous Chondrocyte Transplantation: Biomechanics and Long-Term Durability. https://app.cochat.ai/papers/10.1177/03635465020300011601
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Peterson, L., Brittberg, M., Kiviranta, I., Åkerlund, E. L., & Lindahl, A. (2002). Autologous Chondrocyte Transplantation: Biomechanics and Long-Term Durability. The American Journal of Sports Medicine. https://doi.org/10.1177/03635465020300011601

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