The DOI matches its Crossref record; 103 of the 103 references it cites were found in a registry or an index.
The Epidemiology of Excess Mortality in People with Mental Illness
Open accessAbstract
OBJECTIVE: to investigate the burden of excess mortality among people with mental illness in developed countries, how it is distributed, and whether it has changed over time. METHOD: we conducted a systematic search of MEDLINE, restricting our attention to peer-reviewed studies and reviews published in English relating to mortality and mental illness. Because of the large number of studies that have been undertaken during the last 30 years, we have selected a representative cross-section of studies for inclusion in our review. RESULTS: there is substantial excess mortality in people with mental illness for almost all psychiatric disorders and all main causes of death. Consistently elevated rates have been observed across settings and over time. The highest numbers of excess deaths are due to cardiovascular and respiratory diseases. With life expectancy increasing in the general population, the disparity in mortality outcomes for people with mental illness is increasing. CONCLUSIONS: without the development of alternative approaches to promoting and treating the physical health of people with mental illness, it is possible that the disparity in mortality outcomes will persist.
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“Lawrence et al. (2010) concluded that insufficient health service for schizophrenic patients with cardiovascular disease may explain part of the increased mortality from natural causes.”
From Excess early mortality in schizophrenia. (2014) · cites this paper as Lawrence et al. 2010
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“CVD accounts for much of the excess mortality in psychiatric patients.442”
From 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias (2016) · cites this paper as [442]
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Cites
Suicide as an outcome for mental disorders: A meta-analysis
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Harris, C., & Barraclough, B. (1998) · British Journal of Psychiatry · doi:10.1192/bjp.173.1.11 · Cited by 1,881
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2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw272 · Cited by 3,162
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“Study Selection Studies were included if they (1) were original research papers that used a cohort study design; (2) included diagnosed mental disorders (eg, not symptoms); (3) reported mortality as an outcome by comparing people with mental disorders with a general population or controls from the same study setting w…”
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., et al. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.08.018 · Cited by 1,582
“CVD accounts for much of the excess mortality in psychiatric patients.(442) CVD develops more than a decade earlier in patients with bipolar disorders than in controls.”
BackgroundHjorthøj, C., Stürup, A. E., McGrath, J. J., & Nordentoft, M. (2017) · The Lancet Psychiatry · doi:10.1016/s2215-0366(17)30078-0 · Cited by 1,304
Excess early mortality in schizophrenia.
Laursen, T. M., Nordentoft, M., & Mortensen, P. B. (2014) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032813-153657 · Cited by 913
Metadata
- Authors
- Lawrence, D., Kisely, S., & Pais, J.
- Affiliations
- The Kids Research Institute Australia (AU)
- Professor and Director, The University of Queensland, Health LinQ: The Queensland Centre for Health Data Services, Brisbane, Australia; Professor, Department of Psychiatry, Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia
- The University of Queensland (AU)
- Corresponding author
- Lawrence, David
- Venue
- The Canadian Journal of Psychiatry
- Publisher
- SAGE Publications
- Published
- 2010-12
- Volume
- 55
- Issue
- 12
- Pages
- 752-760
- ISSN
- 0706-7437 (ISSN-L)
- 1497-0015
- OpenAlex
- W149077341
- Cited by
- 258
- References
- 103
- Citations by year
- 2026: 6 · 2025: 11 · 2024: 14 · 2023: 19 · 2022: 16 · 2021: 18 · 2020: 25 · 2019: 16 · 2018: 15 · 2017: 12 · 2016: 19 · 2015: 18 · 2014: 22 · 2013: 24 · 2012: 15
- FWCI
- 1.84
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Canadian Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion, other-oa)
- eSpace (Curtin University) (submittedVersion)
- Griffith Research Online (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- excess mortality, mental illness, cardiovascular disease, respiratory diseases, life expectancy, mortality disparities, physical health of people with mental illness, causes of death
- MeSH terms
- Mental Disorders, Cardiovascular Diseases, Cause of Death, Humans, Respiratory Tract Diseases, Risk Factors, Schizophrenia, Mood Disorders
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