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The Epidemiology of Excess Mortality in People with Mental Illness

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Lawrence, David, Kisely, Stephen, Pais, Joanne·2010·The Canadian Journal of Psychiatry

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Abstract

OBJECTIVE: to investigate the burden of excess mortality among people with mental illness in developed countries, how it is distributed, and whether it has changed over time. METHOD: we conducted a systematic search of MEDLINE, restricting our attention to peer-reviewed studies and reviews published in English relating to mortality and mental illness. Because of the large number of studies that have been undertaken during the last 30 years, we have selected a representative cross-section of studies for inclusion in our review. RESULTS: there is substantial excess mortality in people with mental illness for almost all psychiatric disorders and all main causes of death. Consistently elevated rates have been observed across settings and over time. The highest numbers of excess deaths are due to cardiovascular and respiratory diseases. With life expectancy increasing in the general population, the disparity in mortality outcomes for people with mental illness is increasing. CONCLUSIONS: without the development of alternative approaches to promoting and treating the physical health of people with mental illness, it is possible that the disparity in mortality outcomes will persist.

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See all 258

Authors: Lawrence, D., Kisely, S., & Pais, J.
Affiliations: The Kids Research Institute Australia (AU)
Professor and Director, The University of Queensland, Health LinQ: The Queensland Centre for Health Data Services, Brisbane, Australia; Professor, Department of Psychiatry, Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia
The University of Queensland (AU)
Corresponding author: Lawrence, David
Venue: The Canadian Journal of Psychiatry
Publisher: SAGE Publications
Published: 2010-12
Volume: 55
Issue: 12
Pages: 752-760
ISSN: 0706-7437 (ISSN-L)
1497-0015
DOI: 10.1177/070674371005501202
OpenAlex: W149077341
Cited by: 258
References: 103
Citations by year: 2026: 6 · 2025: 11 · 2024: 14 · 2023: 19 · 2022: 16 · 2021: 18 · 2020: 25 · 2019: 16 · 2018: 15 · 2017: 12 · 2016: 19 · 2015: 18 · 2014: 22 · 2013: 24 · 2012: 15
FWCI: 1.84
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: The Canadian Journal of Psychiatry (publishedVersion)
PubMed (publishedVersion)
UWA Profiles and Research Repository (UWA) (submittedVersion, other-oa)
eSpace (Curtin University) (submittedVersion)
Griffith Research Online (submittedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Keywords: excess mortality, mental illness, cardiovascular disease, respiratory diseases, life expectancy, mortality disparities, physical health of people with mental illness, causes of death
MeSH terms: Mental Disorders, Cardiovascular Diseases, Cause of Death, Humans, Respiratory Tract Diseases, Risk Factors, Schizophrenia, Mood Disorders

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The Epidemiology of Excess Mortality in People with Mental Illness

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