The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Toxicity of carbon nanotubes: A review
Abstract
Carbon nanotubes (CNTs) are widely used in the aerospace, automotive, and electronics industries because of their stability, enhanced metallic, and electrical properties. CNTs are also being investigated for biomedical applications such as drug delivery systems and biosensors. However, the toxic potential of CNTs was reported in various cell lines and animal models. The toxicity depends on diverse properties of the CNTs, such as length, aspect ratio, surface area, degree of aggregation, purity, concentration, and dose. In addition, CNTs and/or associated contaminants were well known for oxidative stress, inflammation, apoptosis, pulmonary inflammation, fibrosis, and granuloma in lungs. The increased production of CNTs likely enhanced the possibility of its exposure in people. Studies on the toxicity of CNTs are mainly focused on the pulmonary effects after intratracheal administration, and only a few studies are reported about the toxicity of CNTs via other routes of exposure. So, it is essential to consider the chronic toxicity of CNTs before using them for various biomedical applications. This review focuses on the potential toxicities of CNTs.
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Cites
Helical microtubules of graphitic carbon
Iijima, S. (1991) · Nature · doi:10.1038/354056a0 · Cited by 43,098
Single-shell carbon nanotubes of 1-nm diameter
Iijima, S., & Ichihashi, T. (1993) · Nature · doi:10.1038/363603a0 · Cited by 9,012
Poland, C. A., Duffin, R., Kinloch, I., Maynard, A., Wallace, W. A. H., Seaton, A., Stone, V., Brown, S., MacNee, W., & Donaldson, K. (2008) · Nature Nanotechnology · doi:10.1038/nnano.2008.111 · Cited by 2,645
Lam, C.-W. (2003) · Toxicological Sciences · doi:10.1093/toxsci/kfg243 · Cited by 1,991
Gas-phase catalytic growth of single-walled carbon nanotubes from carbon monoxide
Nikolaev, P., Bronikowski, M. J., Bradley, R. K., Rohmund, F., Colbert, D. T., Smith, K. A., & Smalley, R. E. (1999) · Chemical Physics Letters · doi:10.1016/s0009-2614(99)01029-5 · Cited by 1,822
Comparative Pulmonary Toxicity Assessment of Single-wall Carbon Nanotubes in Rats
Warheit, D. B. (2003) · Toxicological Sciences · doi:10.1093/toxsci/kfg228 · Cited by 1,515
Cytotoxicity of Carbon Nanomaterials: Single-Wall Nanotube, Multi-Wall Nanotube, and Fullerene
Jia, G., Wang, H., Yan, L., Wang, X., Pei, R., Yan, T., Zhao, Y., & Guo, X. (2005) · Environmental Science & Technology · doi:10.1021/es048729l · Cited by 1,404
Shi Kam, N. W., Jessop, T. C., Wender, P. A., & Dai, H. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0486059 · Cited by 1,352
Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice
Shvedova, A. A., Kisin, E. R., Mercer, R., Murray, A. R., Johnson, V. J., Potapovich, A. I., Tyurina, Y. Y., Gorelik, O., Arepalli, S., Schwegler-Berry, D., et al. (2005) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00084.2005 · Cited by 1,312
Shvedova, A., Castranova, V., Kisin, E., Schwegler-Berry, D., Murray, A., Gandelsman, V., Maynard, A., & Baron, P. (2003) · Journal of Toxicology and Environmental Health, Part A · doi:10.1080/713853956 · Cited by 1,245
Cited by
Carbon-based nanomaterials as an emerging platform for theranostics
Patel, K. D., Singh, R. K., & Kim, H.-W. (2019) · Materials Horizons · doi:10.1039/c8mh00966j · Cited by 555
Mohd Nurazzi, N., Asyraf, M. R. M., Khalina, A., Abdullah, N., Sabaruddin, F. A., Kamarudin, S. H., Ahmad, S., Mahat, A. M., Lee, C. L., Aisyah, H. A., et al. (2021) · Polymers · doi:10.3390/polym13071047 · Cited by 478
Toxicity of Carbon Nanotubes as Anti-Tumor Drug Carriers
Yan, H., Xue, Z., Xie, J., Dong, Y., Ma, Z., Sun, X., Kebebe Borga, D., Liu, Z., & Li, J. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s220087 · Cited by 113
Zhang, T., Tang, M., Yao, Y., Ma, Y., & Pu, Y. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s191689 · Cited by 89
Metadata
- Authors
- Francis, A. P., & Devasena, T.
- Venue
- Toxicology and Industrial Health
- Publisher
- SAGE Publications
- Published
- 2018-03
- Volume
- 34
- Issue
- 3
- Pages
- 200-210
- ISSN
- 0748-2337 (ISSN-L)
- 1477-0393
- OpenAlex
- W2790718622
- Cited by
- 285
- References
- 53
- FWCI
- 11.80
- Type
- journal article
- Language
- en
- Open access
- closed
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