The DOI matches its Crossref record; 91 of the 92 references it cites were found in a registry or an index.
Prefrontal Executive Function Syndromes in Children
Abstract
"Executive function" is a term describing the processes required for conscious control of thought, emotion, and action that are central to the management of one's day-to-day life. Executive function is subserved by the prefrontal cortex and related subcortical structures. Disorders affecting the prefrontal cortex-subcortical system are numerous and heterogeneous, but contemporary research has begun to elucidate the mechanisms and consequences of dysfunction in various subsystems with increasing specificity. Prefrontal executive dysfunction results in impaired regulation of cognition, attention, behaviors, arousal, and emotion, all of which have serious and pervasive consequences for functioning across the life span. These executive function deficits are typically difficult to treat, ameliorate, or remediate and require sensitive handling by caretakers. Executive dysfunction can arise as a consequence of many different factors (metabolic, genetic, certain types of epilepsy, cerebral dysgenesis, prematurity, traumatic brain injury, hypoxia, and toxic exposure). The present review delineates the features of prefrontal executive function deficits in children and proposes a roadmap for their diagnosis, treatment, and management.
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“children may perform within the expected levels on EF tasks in the clinic setting but perform poorly in daily activities that require EF abilities (Powell and Voeller 2004).”
From Characterizing the Factor Structure of Parent Reported Executive Function in Autism Spectrum Disorders: The Impact of Cognitive Inflexibility (2014) · cites this paper as Powell and Voeller 2004
Citations
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Yeates, K. O., Bigler, E. D., Dennis, M., Gerhardt, C. A., Rubin, K. H., Stancin, T., Taylor, H. G., & Vannatta, K. A. (2007) · Psychological Bulletin · doi:10.1037/0033-2909.133.3.535 · Cited by 468
“…hemispheric asymmetries in social-affective behavior; right frontal lesions are associated with excessive emotionality and disinhibited behavior, whereas left frontal lesions are associated with negative emotions, such as depression and fearfulness, as well as withdrawal (Powell & Voeller, 2004).”
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“Several groups have noted deficits in executive functions in children with ADHD ~Bayliss & Roodenrys, 2000; Pennington & Ozonoff, 1996; Powell & Voeller, 2004!”
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“Executive function deficits, although seen in a variety of conditions (Powell & Voeller, 2004), are well known to be associated with ADHD (Willcutt, Doyle, Nigg, Faraone, & Pennington, 2005), and studies have found that children with ADHD show deficits in higher level reading-related skills (Purvis…”
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“Recent research has shown that learning difficulties and behavioral problems are both associated with deficits in executive function (Lezak et al. 2004; Mazzocco and Kover 2007; Pennington and Ozonoff 1996; Powell and Voeller 2004).”
Background
Metadata
- Authors
- Powell, K. B., & Voeller, K. K. S.
- Affiliations
- Western Institute for Neurodevelopmental Studies and Interventions Western Institute for Neurodevelopmental Studies and Interventions, Boulder, CO,
- Western Institute for Neurodevelopmental Studies and Interventions Western Institute for Neurodevelopmental Studies and Interventions, Boulder, CO
- Corresponding author
- Powell, Kristin B.
- Venue
- Journal of Child Neurology
- Publisher
- SAGE Publications
- Published
- 2004-10
- Volume
- 19
- Issue
- 10
- Pages
- 785-797
- ISSN
- 0883-0738 (ISSN-L)
- 1708-8283
- OpenAlex
- W1585151500
- Cited by
- 137
- References
- 92
- Citations by year
- 2025: 3 · 2024: 4 · 2023: 5 · 2022: 6 · 2021: 2 · 2020: 4 · 2019: 6 · 2018: 6 · 2017: 7 · 2016: 9 · 2015: 10 · 2014: 10 · 2013: 7 · 2012: 11
- FWCI
- 2.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Child Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
- Keywords
- executive function, prefrontal cortex, executive dysfunction, children, attention, emotion regulation, arousal, diagnosis, treatment, preterm birth, traumatic brain injury, hypoxia, toxic exposure, cerebral dysgenesis, epilepsy, genetic disorders
- MeSH terms
- Adolescent, Adult, Child, Child Behavior Disorders, Cognition Disorders, Female, Humans, Male, Medical Illustration, Neuropsychological Tests, Syndrome, Prefrontal Cortex
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