Condylomata acuminata in the neovagina after male-to-female reassignment treated with CO 2 laser and imiquimod
Abstract
Condylomata acuminata are frequently occurring genital warts, but little is known about clinical features of the genital warts in transsexuals and their incidence. We report a case of condylomata acuminata arising on the neourethral meatus and the transplanted skin of the neovagina in a male-to-female transsexual, which was successfully treated with CO2 laser irradiation followed by topical application of imiquimod cream on the residual warts. This is a first report of using imiquimod cream for condylomata acuminata arising on the neovagina in a male-to-female transsexual.
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Neovaginal STIs have infrequently been reported and include HSV and HPV/genital warts in penile-inversion vaginoplasty, C. trachomatis in procedures that involved penile skin and grafts with urethra mucosa or abdominal peritoneal lining, and N. gonorrhoeae in both penile-inversion and colovaginoplasty.
“Neovaginal STIs have infrequently been reported in the literature and include HSV and HPV/genital warts in penile-inversion vaginoplasty, C. trachomatis in procedures that involved penile skin and grafts with urethra mucosa or abdominal peritoneal lining (353), and N. gonorrhoeae in both penile-inversion and colovaginoplasty (354–359).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [357]
Cites
Condylomata acuminata of the Neovagina in a HIV-Seropositive Male-to-Female Transsexual
Liguori, G., Trombetta, C. S., Bucci, S., Seta, F. D., Santo, D. D., Siracusano, S., & Belgrano, E. (2004) · Urologia Internationalis · doi:10.1159/000078811 · Cited by 25 · see citing works
<i>Condylomata gigantea</i> in a male transsexual
Yang, C., Liu, S., Xu, K., Xiang, Q., Yang, S., & Zhang, X. (2009) · International Journal of STD & AIDS · doi:10.1258/ijsa.2008.008213 · Cited by 23 · see citing works
Genital warts in a transsexual
Wasef, W., Sugunendran, H., & Alawattegama, A. B. (2005) · International Journal of STD & AIDS · doi:10.1258/0956462053888871 · Cited by 14 · see citing works
Gonorrhoea and condyloma acuminata in a male transsexual.
Fiumara, N. J., & Mattia, A. D. (1973) · Sexually Transmitted Infections · doi:10.1136/sti.49.5.478 · Cited by 8 · see citing works
Condylomata acuminata arising in a neovagina.
Buscema, J., Rosenshein, N. B., & Shah, K. V. (1987) · PubMed · Cited by 8 · see citing works
Successful Treatment of Anal and Perianal Condyloma Acuminata with Imiquimod
Tawada, C., Oshitani, Y., Kimura, M., et al. (2014) · Acta Dermato Venereologica · doi:10.2340/00015555-1636 · Cited by 4 · see citing works
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Sexually Transmitted Infections Treatment Guidelines, 2021
Workowski, K. A., Bachmann, L. H., Chan, P. A., Johnston, C. M., Muzny, C. A., Park, I., Reno, H., Zenilman, J. M., & Bolan, G. A. (2021) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr7004a1 · Cited by 2,759 · see citing works
Chlamydia trachomatis infection of the neovagina in transgender women.
Radix, A. E., Harris, A. B., Belkind, U., Ting, J., & Goldstein, Z. G. (2019) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofz470 · Cited by 30 · see citing works
- Authors
- Matsuki, S., Kusatake, K., Hein, K. Z., Anraku, K., & Morita, E.
- Affiliations
- Shimane University (JP)
- Matsue Red Cross Hospital (JP)
- Venue
- International Journal of STD & AIDS
- Publisher
- SAGE Publications
- Published
- 2014-06-26
- Volume
- 26
- Issue
- 7
- Pages
- 509-511
- ISSN
- 0956-4624 (ISSN-L)
- 1758-1052
- OpenAlex
- W2035476335
- Cited by
- 25
- References
- 6
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 4 · 2022: 3 · 2021: 3 · 2020: 4 · 2019: 2 · 2018: 1 · 2017: 3 · 2016: 2
- FWCI
- 1.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of STD & AIDS (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Genital Health and Disease
- Health Sciences › Medicine › Epidemiology › Cervical Cancer and HPV Research
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Keywords
- genital warts, neovagina, male-to-female transsexuals, CO2 laser therapy, imiquimod, topical immunotherapy, human papillomavirus
- MeSH terms
- Administration, Topical, Aminoquinolines, Condylomata Acuminata, Humans, Male, Transsexualism, Treatment Outcome, Laser Therapy, Ablation Techniques, Young Adult
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