The DOI matches its Crossref record; 44 of the 46 references it cites were found in a registry or an index.
Sustained Striatal Activity Predicts Eudaimonic Well-Being and Cortisol Output
Open accessAbstract
Eudaimonic well-being—a sense of purpose, meaning, and engagement with life—is protective against psychopathology and predicts physical health, including lower levels of the stress hormone cortisol. Although it has been suggested that the ability to engage the neural circuitry of reward may promote well-being and mediate the relationship between well-being and health, this hypothesis has remained untested. To test this hypothesis, we had participants view positive, neutral, and negative images while fMRI data were collected. Individuals with sustained activity in the striatum and dorsolateral prefrontal cortex to positive stimuli over the course of the scan session reported greater well-being and had lower cortisol output. This suggests that sustained engagement of reward circuitry in response to positive events underlies well-being and adaptive regulation of the hypothalamic-pituitary-adrenal axis.
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“Further work has linked purpose to better regulation of physiological systems (e.g., reduced inflammatory markers and cardiovascular risk factors) as well as brain-based mechanisms (e.g., insular cortex volume, reduced amygdala activation, sustained ventral striatum activation) (22 -30).”
From Purpose in life and use of preventive health care services (2014) · cites this paper as [28]
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“As psychotropic medications, such as selective serotonin reuptake inhibitors, have been shown to enhance prefrontal down-regulation of the amygdala in healthy controls (Sladky, Spies, et al., 2015) and in depressed patients (Heller et al., 2013; Maslowsky et al., 2010), medication effects are an important consideration for future research on emotion regulation.”
From Changes in functional connectivity with cognitive behavioral therapy for social anxiety disorder predict outcomes at follow-up (2020) · cites this paper as Heller et al., 2013
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Cites
Development and validation of brief measures of positive and negative affect: The PANAS scales.
Watson, D., Clark, L. A., & Tellegen, A. (1988) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.54.6.1063 · Cited by 32,433
Happiness is everything, or is it? Explorations on the meaning of psychological well-being.
Ryff, C. D. (1989) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.57.6.1069 · Cited by 14,847
Self-citationAdvances in functional and structural MR image analysis and implementation as FSL
Smith, S. M., Jenkinson, M., Woolrich, M. W., Beckmann, C. F., Behrens, T. E. J., Johansen-Berg, H., Bannister, P. R., De Luca, M., Drobnjak, I., Flitney, D. E., et al. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.07.051 · Cited by 13,630
Jenkinson, M., Beckmann, C. F., Behrens, T. E. J., Woolrich, M. W., & Smith, S. M. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2011.09.015 · Cited by 11,314
The structure of psychological well-being revisited.
Ryff, C. D., & Keyes, C. L. M. (1995) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.69.4.719 · Cited by 10,285
Self-citationWell-being : the foundations of hedonic psychology
Kahneman, D. J., Diener, E. F., & Schwarz, N. (1999) · Cited by 7,472
(2005) · CTIT technical reports series · Cited by 5,307
What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?
Berridge, K. C., & Robinson, T. E. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00019-8 · Cited by 4,127
The reorienting system of the human brain: from environment to theory of mind
Corbetta, M., Patel, G., & Shulman, G. L. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.017 · Cited by 3,889
, A. (2010) · Cited by 3,771
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Psychological Well-Being Revisited: Advances in the Science and Practice of Eudaimonia
Ryff, C. D. (2014) · Psychotherapy and Psychosomatics · doi:10.1159/000353263 · Cited by 2,976
Self-citationBerridge, K. C., & Kringelbach, M. L. (2015) · Neuron · doi:10.1016/j.neuron.2015.02.018 · Cited by 1,730
Purpose in life and use of preventive health care services
Kim, E. S., Strecher, V. J., & Ryff, C. D. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1414826111 · Cited by 332
Self-citationEntrepreneurship and eudaimonic well-being: Five venues for new science
Ryff, C. D. (2018) · Journal of Business Venturing · doi:10.1016/j.jbusvent.2018.09.003 · Cited by 358
Self-citationWell-Being With Soul: Science in Pursuit of Human Potential
Ryff, C. D. (2018) · Perspectives on Psychological Science · doi:10.1177/1745691617699836 · Cited by 321
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Metadata
- Authors
- Heller, A. S., van Reekum, C. M., Schaefer, S. M., Lapate, R. C., Radler, B. T., Ryff, C. D., & Davidson, R. J.
- Affiliations
- University of Wisconsin–Madison (US)
- School of Psychology and Clinical Language Sciences, University of Reading
- ORCID
- Venue
- Psychological Science
- Publisher
- SAGE Publications
- Published
- 2013-09-20
- Volume
- 24
- Issue
- 11
- Pages
- 2191-2200
- ISSN
- 0956-7976 (ISSN-L)
- 1467-9280
- PMC
- PMC3866962
- OpenAlex
- W2163186714
- Cited by
- 150
- References
- 46
- Citations by year
- 2026: 9 · 2025: 9 · 2024: 8 · 2023: 13 · 2022: 13 · 2021: 16 · 2020: 16 · 2019: 12 · 2018: 15 · 2017: 13 · 2016: 8 · 2015: 12 · 2014: 5 · 2013: 1
- FWCI
- 12.97
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychological Science (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- CentAUR (University of Reading) (submittedVersion)
- Funders
- National Institute on Aging (P01AG020166)
- National Institute of Mental Health (P50MH084051, R01MH043454)
- National Center for Complementary and Integrative Health (P01AT004952)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (P30HD03352., P30HD003352)
- Topics
- Social Sciences › Psychology › Social Psychology › Psychological Well-being and Life Satisfaction
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- eudaimonic well-being, striatum, reward systems, cortisol, hypothalamic-pituitary-adrenal axis, stress response, dorsolateral prefrontal cortex, positive image, sustained neural activity, meaning in life, emotion regulation
- MeSH terms
- Adult, Aged, Corpus Striatum, Emotions, Female, Humans, Hydrocortisone, Hypothalamo-Hypophyseal System, Magnetic Resonance Imaging, Male, Middle Aged, Personal Satisfaction, Pituitary-Adrenal System, Reward, Saliva, Functional Neuroimaging
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