The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
The Teenage Brain: The Stress Response and the Adolescent Brain
Open accessAbstract
Adolescence is a time of many psychosocial and physiological changes. One such change is how an individual responds to stressors. Specifically, adolescence is marked by significant shifts in hypothalamic-pituitary-adrenal (HPA) axis reactivity, resulting in heightened stress-induced hormonal responses. It is presently unclear what mediates these changes in stress reactivity and what impacts they may have on an adolescent individual. However, stress-sensitive limbic and cortical brain areas that continue to mature during adolescence may be particularly vulnerable to these shifts in responsiveness. Consequently, perturbations of the maturing adolescent brain may contribute to the increase in stress-related psychological dysfunctions, such as anxiety, depression, and drug abuse, often observed during this stage of development. The purpose of this review is to describe the changes that occur in HPA function during adolescence, as well as to briefly discuss the possible ramifications of these changes on the developing brain and psychological health.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Adolescence also appears to be a period of development in which individuals are particularly sensitive to stressors (Broderick and Jennings 2012; Romeo 2013).”
From Mindfulness Interventions to Reduce Impact of Interparental Conflict on Adolescents. (2020) · cites this paper as Romeo 2013
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Effects of stress throughout the lifespan on the brain, behaviour and cognition
Lupien, S. J., McEwen, B. S., Gunnar, M. R., & Heim, C. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2639 · Cited by 6,256
The adolescent brain and age-related behavioral manifestations
Spear, L. P. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(00)00014-2 · Cited by 5,433
Physiology and neurobiology of stress and adaptation: central role of the brain
McEwen, B. S. (2007) · Physiological Reviews · doi:10.1152/physrev.00041.2006 · Cited by 5,429 · cited 3×
“Neurons in the amygdala, conversely, show stress-induced growth in adulthood, along with increased amygdala-dependent fear learning (McEwen, 2007).”
BackgroundInfluentialStress, adaptation, and disease. Allostasis and allostatic load
McEWEN, B. S. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb09546.x · Cited by 5,092
Herman, J. P., Figueiredo, H., Mueller, N. K., Ulrich-Lai, Y., Ostrander, M. M., Choi, D. C., & Cullinan, W. E. (2003) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2003.07.001 · Cited by 1,586
Sapolsky, R. M., & Meaney, M. J. (1986) · Brain Research Reviews · doi:10.1016/0165-0173(86)90010-x · Cited by 999
Structural MRI of pediatric brain development: what have we learned and where are we going?
Giedd, J. N., & Rapoport, J. L. (2010) · Neuron · doi:10.1016/j.neuron.2010.08.040 · Cited by 836
Functional Cross‐Talk Between the Hypothalamic‐Pituitary‐Gonadal and ‐Adrenal Axes
Viau, V. (2002) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2002.00798.x · Cited by 744
Gunnar, M. R., Wewerka, S., Frenn, K., Long, J. D., & Griggs, C. (2009) · Development and Psychopathology · doi:10.1017/s0954579409000054 · Cited by 668
Stress response and the adolescent transition: performance versus peer rejection stressors
Stroud, L. R., Foster, E., Papandonatos, G. D., Handwerger, K., Granger, D. A., Kivlighan, K. T., & Niaura, R. (2009) · Development and Psychopathology · doi:10.1017/s0954579409000042 · Cited by 610
Research works printed but not linked: 1
- Sapolsky R. M., 1986, Brain Research Reviews, 396, 64
Cited by
Sorted by citations
Sensitive periods of substance abuse: Early risk for the transition to dependence
Jordan, C. J., & Andersen, S. L. (2017) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2016.10.004 · Cited by 455
“Adolescent rats, especially females, are yper-responsive to stressors and take longer to return to baseine after provocation (Lupien et al., 2009; Romeo and McEwen, 006; Romeo, 2013).”
Casey, B. J., & Caudle, K. (2013) · Current Directions in Psychological Science · doi:10.1177/0963721413480170 · Cited by 412
Tone, E. B., & Tully, E. C. (2014) · Development and Psychopathology · doi:10.1017/s0954579414001199 · Cited by 253
The Need to Contribute During Adolescence
Fuligni, A. J. (2018) · Perspectives on Psychological Science · doi:10.1177/1745691618805437 · Cited by 258
Romeo, R. D. (2016) · Brain Research · doi:10.1016/j.brainres.2016.03.021 · Cited by 226
Self-citation
Metadata
- Authors
- Romeo, R. D.
- Affiliations
- Columbia University (US)
- Corresponding author
- Romeo, Russell D.
- ORCID
- Romeo, Russell D.
- Venue
- Current Directions in Psychological Science
- Publisher
- SAGE Publications
- Published
- 2013-04
- Volume
- 22
- Issue
- 2
- Pages
- 140-145
- ISSN
- 0963-7214 (ISSN-L)
- 1467-8721
- PMC
- PMC4274618
- OpenAlex
- W2103027336
- Cited by
- 343
- References
- 28
- Citations by year
- 2026: 43 · 2025: 29 · 2024: 35 · 2023: 39 · 2022: 39 · 2021: 43 · 2020: 23 · 2019: 19 · 2018: 26 · 2017: 11 · 2016: 15 · 2015: 11 · 2014: 7 · 2013: 3
- FWCI
- 5.47
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Current Directions in Psychological Science (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R03MH090224)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- adolescence, hypothalamic-pituitary-adrenal axis, stress reactivity, adolescent brain development, cortical maturation, anxiety, depression, drug abuse
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
