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Cited by 2,970

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Matrix Metalloproteinases: A Review

Birkedal-Hansen, H., Moore, W.G.I., Bodden, M.K., Windsor, L.J., Birkedal-Hansen, B., DeCarlo, A., Engler, J.A.·1993·Critical Reviews in Oral Biology & Medicine

Abstract

Matrix metalloproteinases (MMPs) are a family of nine or more highly homologous Zn++endopeptidases that collectively cleave most if not all of the constituents of the extracellular matrix. The present review discusses in detail the primary structures and the overlapping yet distinct substrate specificities of MMPs as well as the mode of activation of the unique MMP precursors. The regulation of MMP activity at the transcriptional level and at the extracellular level (precursor activation, inhibition of activated, mature enzymes) is also discussed. A final segment of the review details the current knowledge of the involvement of MMP in specific developmental or pathological conditions, including human periodontal diseases.

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Crossref · 10.1177/10454411930040020401

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Metadata

Authors
Birkedal-Hansen, H., Moore, W. G. I., Bodden, M. K., Windsor, L. J., Birkedal-Hansen, B., DeCarlo, A., & Engler, J. A.
Venue
Critical Reviews in Oral Biology & Medicine
Published
1993-01
Volume
4
Issue
2
Pages
197-250
ISSN
  • 1045-4411 (ISSN-L)
  • 1544-1113
OpenAlex
W1894541755
Cited by
2,970
References
3
FWCI
63.49
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Matrix Metalloproteinases: A Review. https://app.cochat.ai/papers/10.1177/10454411930040020401
The paper
Birkedal-Hansen, H., Moore, W. G. I., Bodden, M. K., Windsor, L. J., Birkedal-Hansen, B., DeCarlo, A., & Engler, J. A. (1993). Matrix Metalloproteinases: A Review. Critical Reviews in Oral Biology & Medicine. https://doi.org/10.1177/10454411930040020401

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.