The DOI matches its Crossref record; 104 of the 104 references it cites were found in a registry or an index.
Oxidative Injury and Inflammatory Periodontal Diseases : the Challenge of Anti-Oxidants to Free Radicals and Reactive Oxygen Species
Open accessAbstract
In recent years, there has been a tremendous expansion in medical and dental research concerned with free radicals, reactive oxygen species, and anti-oxidant defense mechanisms. This review is intended to provide a critical, up-to-date summary of the field, with particular emphasis on its implications for the application of "anti-oxidant therapy" in periodontal disease. We have reviewed the nomenclature, mechanisms of actions, features, and sources of most common free radicals and reactive oxygen species, as well as analyzed the typical biological targets for oxidative damage. Based on a review of direct and indirect anti-oxidant host defenses, particularly in relation to the key role of polymorphonuclear neutrophils in periodontitis, we review current evidence for oxidative damage in chronic inflammatory periodontal disease, and the possible therapeutic effects of anti-oxidants in treating and/or preventing such pathology, with special attention to vitamin E and Co-enzyme Q.
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Cites
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Cited by
The antioxidant capacity of saliva
Battino, M., Ferreiro, M. S., Gallardo, I., Newman, H. N., & Bullon, P. (2002) · Journal of Clinical Periodontology · doi:10.1034/j.1600-051x.2002.290301x.x · Cited by 342
Self-citationMicronutritional approaches to periodontal therapy
Van der Velden, U., Kuzmanova, D., & Chapple, I. L. C. (2011) · Journal of Clinical Periodontology · doi:10.1111/j.1600-051x.2010.01663.x · Cited by 199
Atsumi, T., Fujisawa, S., Nakabayashi, Y., Kawarai, T., Yasui, T., & Tonosaki, K. (2004) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(03)00064-3 · Cited by 21
Metadata
- Authors
- Battino, M., Bullon, P., Wilson, M., & Newman, H.
- Venue
- Critical Reviews in Oral Biology & Medicine
- Publisher
- SAGE Publications
- Published
- 1999-07
- Volume
- 10
- Issue
- 4
- Pages
- 458-476
- ISSN
- 1045-4411 (ISSN-L)
- 1544-1113
- OpenAlex
- W2138579034
- Cited by
- 339
- References
- 104
- FWCI
- 5.17
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Oxidative Injury and Inflammatory Periodontal Diseases : the Challenge of Anti-Oxidants to Free Radicals and Reactive Oxygen Species. https://app.cochat.ai/papers/10.1177/10454411990100040301
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- Battino, M., Bullon, P., Wilson, M., & Newman, H. (1999). Oxidative Injury and Inflammatory Periodontal Diseases : the Challenge of Anti-Oxidants to Free Radicals and Reactive Oxygen Species. Critical Reviews in Oral Biology & Medicine. https://doi.org/10.1177/10454411990100040301
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
