The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
A review of the pharmacotherapy of adults with Attention-Deficit/ Hyperactivity Disorder
Abstract
Objective: Despite the increasing recognition of attention deficit hyperactivity disorder (ADHD) in adults, the use of pharmacotherapeutics remains less established. Methods: A systematic review of the literature identified 15 studies (N = 435 subjects) of stimulants, and 22 studies of non- stimulant medications (N = 421 subjects) including antidepressants, antihypertensives, amino acids, and wake-promoting agents for the treatment of ADHD in adults. Results: Studies with stimulants and antidepressants demonstrated significant short-term improvement in ADHD symptoms compared to placebo in adults. Methylphenidate (MPH) and amphetamine had an immediate onset of action whereas the ADHD response to pemoline and antidepressants appeared delayed. The response to amphetamine and MPH appears to be dose-dependent. Controlled data on nicotonic and noradrenergic compounds appear promising. There was considerable variability In diagnostic criteria, dosing parameters, and response rates between the various studies. Conclusions: Under controlled conditions, the aggregate literature shows that the stimulants and noradrenergic antidepressants had a clinically and statistically significant beneficial effect on treating ADHD in adults.
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Citations
Cites
Executive functions and developmental psychopathology.
Pennington, B. F., & Ozonoff, S. (1996) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1996.tb01380.x · Cited by 3,150 · cited 1×
“…in the inattentive cluster of symptoms relative to the hyperactive/impulsive symptoms and improvement in higher level executive functioning (Pennington & Ozonoff, 1996), which is of great importance given findings of prominent executive dysfunction in adults with ADHD (Brown & Quinlan,…”
BackgroundBiederman, J. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.816 · Cited by 1,498
Self-citation(1993) · American Journal of Psychiatry · doi:10.1176/ajp.150.6.885 · Cited by 1,421
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“A bidirectional overrepresentation of comorbidity within ADHD has been reported with adults with ADHD manifesting higher rates of anxiety, depression, and substance use disorders than non-ADHD adults {Sljekim, Asamow, Hess, Zaucha, & Wheeler, 1990; Biederman et al., 1993).”
BackgroundSelf-citationHart, E. L., Lahey, B. B., Loeber, R., Applegate, B., & Frick, P. J. (1995) · Journal of Abnormal Child Psychology · doi:10.1007/bf01447474 · Cited by 590
Hyperactive Boys Almost Grown Up: V. Replication of Psychiatric Status
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Cited by
sagvolden, T., johansen, E. B., aase, H., & russell, V. A. (2005) · Behavioral and Brain Sciences · doi:10.1017/s0140525x05000075 · Cited by 1,035
Cognitive-behavioral therapy for ADHD in medication-treated adults with continued symptoms
Safren, S. A., Otto, M. W., Sprich, S., Winett, C. L., Wilens, T. E., & Biederman, J. (2005) · Behaviour Research and Therapy · doi:10.1016/j.brat.2004.07.001 · Cited by 519
Self-citationFaraone, S. V., Spencer, T., Aleardi, M., Pagano, C., & Biederman, J. (2004) · Journal of Clinical Psychopharmacology · doi:10.1097/01.jcp.0000108984.11879.95 · Cited by 404
Self-citationEfficacy of meta-cognitive therapy for adult ADHD
Solanto, M. V., Marks, D. J., Wasserstein, J., Mitchell, K., Abikoff, H., Alvir, J. M. J., & Kofman, M. D. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.09081123 · Cited by 370
SCHOECHLIN, C., & ENGEL, R. (2005) · Archives of Clinical Neuropsychology · doi:10.1016/j.acn.2005.04.005 · Cited by 312
Metadata
- Authors
- Wilens, T. E., Spencer, T. J., & Biederman, J.
- Venue
- Journal of Attention Disorders
- Publisher
- SAGE Publications
- Published
- 2001-11
- Volume
- 5
- Issue
- 4
- Pages
- 189-202
- ISSN
- 1087-0547 (ISSN-L)
- 1557-1246
- OpenAlex
- W2000804661
- Cited by
- 190
- References
- 16
- FWCI
- 3.04
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
