Impact of ADHD in Adults With Neurofibromatosis Type 1: Associated Psychological and Social Problems
Abstract
OBJECTIVE: To analyze the psychological phenotype of ADHD, and the effect of ADHD on life satisfaction and personality in adults with neurofibromatosis type 1 (NF1). METHOD: Adults with NF1 without (n = 26) and with ADHD (n = 22), and adults with ADHD only (n = 27) completed questionnaires on personality traits and life satisfaction. Differences between groups were analyzed. RESULTS: Participants with NF1 and ADHD present an emotionally instable psychological phenotype similar to adults with ADHD only, which differed significantly from that in adults with NF1 only. Participants with NF1 and ADHD had significantly lower overall life satisfaction than NF1 participants without such symptoms, affecting general health, self-satisfaction, sexuality, and family. CONCLUSION: The authors' findings show that ADHD symptoms can persist through adulthood. These NF1 patients display problems similar to those of adults with ADHD only. This finding is highly relevant to understand the behavioral and psychological phenotype in adults with NF1 and to offer psychological and/or medical treatment.
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Patients with NF1 exhibit high rates of attention-deficit/hyperactivity disorder.
“Patients with NF1 exhibit high rates of attention-deficit/hyperactivity disorder (Mautner et al., 2015; Miguel et al., 2015)”
From Ventral striatum dopamine release encodes unique properties of visual stimuli in mice (2023) · cites this paper as Mautner et al., 2015
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- Authors
- Mautner, V.-F., Granström, S., & Leark, R. A.
- Affiliations
- University Medical Center Hamburg-Eppendorf (DE)
- Alliant University (US)
- Venue
- Journal of Attention Disorders
- Publisher
- SAGE Publications
- Published
- 2012-07-10
- Volume
- 19
- Issue
- 1
- Pages
- 35-43
- ISSN
- 1087-0547 (ISSN-L)
- 1557-1246
- OpenAlex
- W1985047628
- Cited by
- 39
- References
- 31
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 4 · 2023: 4 · 2022: 4 · 2021: 2 · 2020: 5 · 2018: 2 · 2017: 3 · 2016: 2 · 2015: 3 · 2014: 1 · 2013: 1 · 2012: 1
- FWCI
- 1.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Attention Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Health Sciences › Medicine › Neurology › Neurofibromatosis and Schwannoma Cases
- Health Sciences › Medicine › Neurology › Neuroblastoma Research and Treatments
- Keywords
- attention deficit hyperactivity disorder, neurofibromatosis type 1, adults, life satisfaction, personality traits, neuroticism, comorbidities
- MeSH terms
- Adult, Attention Deficit Disorder with Hyperactivity, Mental Disorders, Emotions, Female, Humans, Male, Middle Aged, Neurofibromatosis 1, Personal Satisfaction, Personality Inventory, Phenotype, Quality of Life, Surveys and Questionnaires, Social Behavior, Social Problems, Socioeconomic Factors, Case-Control Studies
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