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Innovative technology-based interventions for autism spectrum disorders: A meta-analysis
Abstract
This article reports the results of a meta-analysis of technology-based intervention studies for children with autism spectrum disorders. We conducted a systematic review of research that used a pre-post design to assess innovative technology interventions, including computer programs, virtual reality, and robotics. The selected studies provided interventions via a desktop computer, interactive DVD, shared active surface, and virtual reality. None employed robotics. The results provide evidence for the overall effectiveness of technology-based training. The overall mean effect size for posttests of controlled studies of children with autism spectrum disorders who received technology-based interventions was significantly different from zero and approached the medium magnitude, d = 0.47 (confidence interval: 0.08-0.86). The influence of age and IQ was not significant. Differences in training procedures are discussed in the light of the negative correlation that was found between the intervention durations and the studies' effect sizes. The results of this meta-analysis provide support for the continuing development, evaluation, and clinical usage of technology-based intervention for individuals with autism spectrum disorders.
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“In that way, the presented approach is aligned with the recommendations made by Grynszpan et al. (2014) for the design of more accessible interventions.”
From iSenseVR: bringing VR exposure therapy outside the laboratory (2019) · cites this paper as Grynszpan et al. (2014)
In the citing paper
“Games for children with ASD-related symptoms showed comparable moderate effect as found by Grynszpan et al. (85) for technology-based (non-serious gaming) interventions for children with autism spectrum-related symptoms (d = 0.47).”
From Serious Games for Mental Health: Are They Accessible, Feasible, and Effective? A Systematic Review and Meta-analysis (2017) · cites this paper as [85]
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“dren with ASD appear to have a special interest in computerized activities (Grynszpan et al. 2014), and has identified the advantages that computers provide with regard to the core deficits of ASD.”
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Measuring the Efficacy of Robots in Autism Therapy
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“…reviews and a meta-analysis of the technology-based interventions for IwASDs (which reviewed research articles published before December 2011) have concluded that the robot based studies with IwASDs fail to meet a set of criteria commonly observed to assess the outcome of an ASD therapy [13, 23].”
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“At the same time, it supports the fact that there is an increasing tendency, in the literature, to technologically based applications in teaching various skills to individuals with ASD (Grynszpan et al., 2014).”
Hatfield, M., Falkmer, M., Falkmer, T., & Ciccarelli, M. (2017) · Child and Adolescent Psychiatry and Mental Health · doi:10.1186/s13034-017-0191-2 · Cited by 49
“A meta-analysis of the effectiveness of technology-based programs for adolescents on the autism spectrum found that programs that were entirely self-directed by participants had a smaller effect than programs administered by a specialist [32].”
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“In the field of special education, technology has become an integral part of the education of children with disabilities and research in this area has grown considerably (Grynszpan et al., 2014; Heng et al., 2020).”
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“Advocated in Grynszpan et al. (2014) ’ s meta-analysis on technology-enabled interventions for ASD, the e ff ectiveness of technology-enabled interventions is promising, but further development and evaluation are needed.”
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“Research indicates technology instruction has many advantages for learners with ASD (Grynszpan et al., 2014).”
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“A meta-analysis from Grynszpan et al. (2014) suggested that technology-based interventions focused on improving ‘social skills’ had limited efficacy.”
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“…reviews and perspectives (Lorah et al. 2015; McCleery 2015; Odom et al. 2015; Stephenson and Limbrick 2015; Whyte et al. 2015) which add to our knowledge about trends in technologies for autism research and clinical practice (e.g. see Grynszpan et al. 2014; Kientz et al. 2013; Boser et al. 2013).”
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“…be carried out (e.g., demonstrating their learning orally or in writing), deadlines, or the allotted time offered to complete an activity (Becker et al., 2016; Grynszpan et al., 2014; Hughes et al., 2019; C. S. Martin, 2016; Oliver-Kerrigan et al., 2021; Sansosti et al., 2015; Stokes et al., 2017).”
The Role of Body Postures in the Recognition of Emotions in Contextually Rich Scenarios
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“Besides evidence-based interventions, recent studies suggested that virtual reality (VR) technology could be a promising medium to deliver interventions for ASD [15,16].”
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“Technology-based autism interventions have recently advanced appreciably (Grynszpan et al., 2014), among which augmented reality (AR) is one of the most promising technologies, well suited to improve social skills in children with an autism diagnosis (Mosher et al., 2021).”
Grynszpan, O., & Nadel, J. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.01067 · Cited by 31
“The last decade has witnessed a steep increase in the number of projects devoted to innovative technologies for evaluating, assisting or training individuals with ASD (Grynszpan et al., 2014).”
Hatfield, M., Falkmer, M., Falkmer, T., & Ciccarelli, M. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3317-8 · Cited by 43
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“Information and communications technologies have long been seen as holding promise for addressing the socio-communicative and behavioral needs of people with ASD (Beaumont and Sofronoff 2008; Durkin 2010; Grynszpan et al. 2014; Knight et al. 2013; Parsons 2016).”
BackgroundInfluentialSerious Games: A Concise Overview on What They Are and Their Potential Applications to Healthcare
Giunti, G., Analía, B., Giunta, D. H., Plazzotta, F., Benítez, S., Adrián, G., Luna, D. R., & Fernan, G. B. D. Q. (2015) · Studies in health technology and informatics · doi:10.3233/978-1-61499-564-7-386 · Cited by 29
JEMImE: A Serious Game to Teach Children with ASD How to Adequately Produce Facial Expressions
Dapogny, A., Grossard, C., Hun, S., Serret, S., Bourgeois, J., Jean-Marie, H., Foulon, P., Ding, H., Chen, L., Dubuisson, S., et al. (2018) · International Conference on Automatic Face and Gesture Recognition · doi:10.1109/fg.2018.00114 · Cited by 28
“(2014) [8] reports that results of intervention based on ICTs are promising.”
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Digital interventions for autism spectrum disorders: A systematic review and meta‐analysis
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“16,54 Besides, the inclusion and exclusion criteria, type of control group, pretest and posttest design, and innovative digital interventions could contribute to different effect sizes.”
Cerero, J. F., Rueda, M. M., & Menéses, E. L. (2024) · Children · doi:10.3390/children11091062 · Cited by 50
“…and the adequate allocation of resources to address diversity in classrooms is noted, highlighting the need for a collaborative and purposeful approach to ensure that all students have the opportunity to reach their full potential in an appropriately supported and accessible learning environment.”
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Ntalindwa, T., Soron, T. R., Nduwingoma, M., Karangwa, E., & White, R. (2019) · JMIR Pediatrics and Parenting · doi:10.2196/12176 · Cited by 26
“In addition to other research [51,52], this study recommends further exploration into LMICs such as Sub-Saharan Africa.”
Banire, B., Al‐Thani, D., Qaraqe, M., Khowaja, K., & Mansoor, B. (2020) · IEEE Access · doi:10.1109/access.2020.3045042 · Cited by 32
Pervin, M. M., Ahmed, H. U., & Hagmayer, Y. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.834783 · Cited by 35
Löytömäki, J., Ohtonen, P. P., & Huttunen, K. H. (2023) · British Journal of Educational Technology · doi:10.1111/bjet.13420 · Cited by 25
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“These include the use of computer-assisted instruction (e.g., Grynszpan et al., 2014; Knight et al., 2013; Pennington, 2010; Ramdoss et al., 2011; Root et al., 2017) and methods for improving reading comprehension—an area of weakness for many children with autism—that go well beyond those…”
MethodReducing Information’s Speed Improves Verbal Cognition and Behavior in Autism: A 2-Cases Report
Tardif, C., Latzko, L., Arciszewski, T., & Gepner, B. (2017) · PEDIATRICS · doi:10.1542/peds.2015-4207 · Cited by 25
Personalized Recommendation of PoIs to People with Autism
Mauro, N., Ardissono, L., & Cena, F. (2020) · ACM Conference on User Modeling, Adaptation and Personalization (UMAP) · doi:10.1145/3340631.3394845 · Cited by 24
“Moreover, specifically the HCI community prefers to address social interaction problems [21, 27, 36], likely because these are seen as the core characteristics of autism from a clinical point of view: therefore, that research focuses, e.”
BackgroundGiraud, T., Ravenet, B., Dang, C. T., Nadel, J., Prigent, E., Poli, G., André, E., & Martin, J. (2021) · International Conference on Tangible, Embedded, and Embodied Interaction (TEI) · doi:10.1145/3430524.3440646 · Cited by 24
“As interactive systems are perceived by children with ASD as stimulating and trustworthy environments [4, 5], many researchers have designed technology-based interventions.”
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“…been used to improve a wide range of social, cognitive, and adaptive skills for children with ASD, research is needed on treatment efficacy and heterogeneity due to the diverse array of interactive technology platforms and multiple intervention strategies they encompass (Grynszpan et al., 2014).”
InfluentialGriffin, J. W., Geier, C. F., Smyth, J. M., & Scherf, K. S. (2021) · JCPP Advances · doi:10.1002/jcv2.12041 · Cited by 22
“The magnitude of these treatment effects is on par with those identified from meta ‐ analyses of computer ‐ based interventions for autism (Grynszpan et al., 2014; Tang et al., 2019).”
Ip, H. H. S., Lai, C. H.-Y., Wong, S. W. L., Tsui, J. K. Y., Li, C., Lau, K. S.-Y., & Chan, D. F. Y. (2017) · Cogent Education · doi:10.1080/2331186x.2017.1307709 · Cited by 26
Anxiety in high-functioning autism: A pilot study of experience sampling using a mobile platform
Hare, D. J., Gracey, C., & Wood, C. (2016) · Autism · doi:10.1177/1362361315604817 · Cited by 22
“…with everyday issue in everyday contexts (Gaus, 2011), the use of technology-based interventions, ranging from virtual reality environments to mobile platforms (Grynszpan et al., 2014) to mobile technology such as the personal digital assistant (PDA), would appear to be worthy of consideration.”
BackgroundSupporting people with autism spectrum disorders in the exploration of PoIs
Mauro, N., Ardissono, L., & Cena, F. (2022) · Communications of the ACM · doi:10.1145/3505267 · Cited by 22
“22 Sight, smell, and hearing are relevant to mobility in urban environments, and high sensory and the difficulty level of the activities is manually set by the therapist.”
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Teaching Facial Expression Production in Autism: The Serious Game JEMImE
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“Since children with autism are very interested in technological devices [7], such as personal computers, smartphones, tablets, and robots, several studies proposed using these devices in screening, assessment, and rehabilitation of children with autism [8]–[10].”
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Desideri, L. (2017) · doi:10.31234/osf.io/3fvr6 · Cited by 22
Customization Support in Computer-Based Technologies for Autism: A Systematic Mapping Study
Lopez-Herrejon, R. E., Poddar, O., Herrera, G., & Sevilla, J. (2020) · International Journal of Human-Computer Interaction · doi:10.1080/10447318.2020.1731673 · Cited by 21
“This fact could be appreciated in the large number of studies that have been published in the recent years, for example, please refer to Bereznak et al. (2012), Grynszpan et al. (2014), Hourcade et al. (2013), Kagohara et al. (2013), Stephenson and Limbrick (2015), Wainer and Ingersoll (2011).”
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Yakubova, G., Leibowitz, L., Chen, B. B., Halawani, N., & Harpole, L. L. (2019) · Advances in Neurodevelopmental Disorders · doi:10.1007/s41252-019-0097-5 · Cited by 21
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Autism and Socially Interactive Agents
Nadel, J., Grynszpan, O., & Martin, J. (2022) · ACM eBooks · doi:10.1145/3563659.3563673 · Cited by 20
“A review has been published on the training of skills assisted by digital technologies in autism [Grynszpan et al. 2014].”
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Potential clinical impact of positive affect in robot interactions for autism intervention
Kim, E. S., Daniell, C. M., Makar, C., Elia, J., Scassellati, B., & Shic, F. (2015) · Affective Computing and Intelligent Interaction · doi:10.1109/acii.2015.7344544 · Cited by 20
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Siyam, N., & Abdallah, S. (2021) · Journal of Special Education Technology · doi:10.1177/01626434211033581 · Cited by 25
“Technology for education purposes covered various topics and skills including general education, cognitive abilities, literacy skills, academic skills, communication skills, social skills, functional skills, and emotion recognition (Grynszpan et al., 2014).”
BackgroundThe Use of Technologies Among Individuals With Autism Spectrum Disorders: Barriers and Challenges
Ghanouni, P., Jarus, T., Zwicker, J. G., & Lucyshyn, J. M. (2019) · Journal of Special Education Technology · doi:10.1177/0162643419888765 · Cited by 28
Denizli-Gulboy, H., Genc‐Tosun, D., & Gülboy, E. (2021) · International Journal of Developmental Disabilities · doi:10.1080/20473869.2021.1972741 · Cited by 19
“Nowadays, these technological devices are commonly used as teaching material by individuals with ASD in different age groups (Grynszpan et al. 2014).”
BackgroundVideo-Based Virtual Reality Technology for Autistic Users: An Emerging Technology Report
Glaser, N. J., Newbutt, N. A., Palmer, H., & Schmidt, M. (2022) · Technology Knowledge and Learning · doi:10.1007/s10758-022-09594-x · Cited by 19
“…in part due to the significant challenges of designing VR experiences for people with autism (Glaser et al., 2021; Schmidt et al., 2019), which includes the need for highly technical development skills and, in some cases, prohibitive hardware costs (Grynszpan et al., 2014; Schmidt & Glaser, 2021).”
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“Evidence indicates that the use of technology is most effective when highly individualized and coupled with personal interaction with a professional (Grynszpan et al., 2014; Ke & Im, 2013).”
Extended Reality Guidelines for Supporting Autism Interventions Based on Stakeholders’ Needs
Bauer, V., Bouchara, T., & Bourdot, P. (2022) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-022-05447-9 · Cited by 19
The Landscape of Technology Research in Special Education: A Bibliometric Analysis
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“Individuals with ASD can be provided with a suitable, encouraging, consistent, and dependable learning environment with technology.”
BackgroundMethodInfluentialVirtual reality and robots for autism: moving beyond the screen
Good, J., Parsons, S., Yuill, N., & Brosnan, M. (2016) · Journal of Assistive Technologies · doi:10.1108/jat-09-2016-0018 · Cited by 18
“Many of these technologies have taken the form of targeted instruction or interventions which address the core deficits associated with autism (Odom et al., 2015; Grynszpan et al., 2014; Fletcher-Watson, 2014).”
BackgroundPart 2: The virtual environment social program for youths with autism spectrum disorder.
MacCormack, J. W. H., & Freeman, J. (2019) · International Journal of Play Therapy · doi:10.1037/pla0000093 · Cited by 22
Technology-Aided Interventions for Individuals With Autism: Implications for Policy and Practice
Pham, A. V., Bennett, K. D., & Zetina, H. (2019) · Policy Insights from the Behavioral and Brain Sciences · doi:10.1177/2372732219857750 · Cited by 18
“Another category of technology-aided interventions, CAI, has been used to teach academic, social, and behavioral skills to students with disabilities (Barton, Pustejovsky, Maggin, & Reichow, 2017; Grynszpan et al., 2014; Sansosti, Doolan, Remaklus, Krupko, & Sansosti, 2015).”
BackgroundInfluentialCao, Y., He, Y., Chen, Y., Chen, M., You, S., Qiu, Y., Liu, M.-L., Luo, C., Chen, Z., Tong, X., et al. (2025) · ACM International Conference on Intelligent User Interfaces (IUI) · doi:10.1145/3708359.3712142 · Cited by 18
“Moreover, existing programs often focus on specifc s without adequately explaining the underlying reasons for s cues, raising concerns about the generalizability of these inter tions [51, 107].”
Garcia, J. M., Leahy, N. A., Brazendale, K., Quelly, S. B., & Lawrence, S. A. (2020) · Disability and health journal · doi:10.1016/j.dhjo.2020.100990 · Cited by 17
Meta-Analysis of RCTs of Technology-Assisted Parent-Mediated Interventions for Children with ASD
Pi, H. J., Kallapiran, K., Munivenkatappa, S., Kandasamy, P., Kirubakaran, R., Russell, P. S. S., & Eapen, V. (2021) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-021-05206-2 · Cited by 20
Farroni, T., Valori, I., & Carnevali, L. (2022) · Brain Sciences · doi:10.3390/brainsci12020147 · Cited by 16
Translating neuroscience to the front lines: point-of-care detection of neuropsychiatric disorders
Dasgupta, J., Bhavnani, S., Estrin, G. L., Mukherjee, D., Banerjee, A., Belmonte, M. K., Chakrabarti, B., Divan, G., Dawson, G., Johnson, M. H., et al. (2016) · The Lancet Psychiatry · doi:10.1016/s2215-0366(16)30186-9 · Cited by 16
Gu, P., Xu, X., Qian, X., & Weng, T. (2022) · IEEE Transactions on Learning Technologies · doi:10.1109/tlt.2022.3197430 · Cited by 17
“[27] conducted a meta-analysis of technology-based intervention studies for autistic children published between 1990 and 2011 and reported an overall effect size of 47, suggesting this type of intervention can yield clinically significant improvements.”
MethodHatfield, M., Falkmer, M., Falkmer, T., & Ciccarelli, M. (2016) · Child and Adolescent Psychiatry and Mental Health · doi:10.1186/s13034-016-0137-0 · Cited by 25
“A metaanalysis of technology-based training for people with autism supported the effectiveness of these interventions and advocated their use with this population [37].”
MethodThompson, J., Plavnick, J. B., & Skibbe, L. E. (2018) · The Journal of Special Education · doi:10.1177/0022466918796504 · Cited by 20
Atturu, H., Naraganti, S., & Rao, B. R. (2025) · JMIR Neurotechnology · doi:10.2196/70589 · Cited by 23
“The CognitiveBotics software, like many other available ABA-assistive technologies, was observed to have various benefits and advantages specifically for individuals with ASD [50].”
Bellon-Harn, M. L., & Manachaiah, V. (2021) · Online Learning · doi:10.24059/olj.v25i2.2204 · Cited by 18
“Web-based or mobile app programs may offer guidance, support, and information to students with ASD (Backman et al., 2018; Bölte et al., 2010; Grynszpan et al., 2014; Tobin et al., 2014).”
BackgroundMauro, N., Ardissono, L., Cocomazzi, S., & Cena, F. (2022) · Expert Systems with Applications · doi:10.1016/j.eswa.2022.116972 · Cited by 16
On the Evaluation of Engagement in Immersive Applications When Users Are on the Autism Spectrum
Tarantino, L., Attanasio, M., Mascio, T. D., Gasperis, G. D., Valenti, M., & Mazza, M. (2023) · Sensors · doi:10.3390/s23042192 · Cited by 16
“…robust studies with strong methodologies and the lack of proof for generalization [17], the little evidence supporting the efficacy of VR technology [18], and the need of more research within educational and clinical settings to ensure robust recommendations can be made on the implementation, use…”
BackgroundSchmidt, M., Glaser, N. J., Schmidt, C. T., Kaplan, R. L., Palmer, H., & Cobb, S. V. G. (2023) · Computers & Education X Reality · doi:10.1016/j.cexr.2023.100013 · Cited by 16
Cordeiro, R., Ferreira, W. S., Aguiar, Y. P. C., Saraiva, J. D. A. G., Tardif, C., & Galy, É. (2018) · Brazilian Symposium on Human Factors in Computing Systems (IHC) · doi:10.1145/3274192.3274229 · Cited by 16
Lamash, L., Little, L. M., & Hen‐Herbst, L. (2022) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-022-05440-2 · Cited by 19
Groba, B., Nieto-Riveiro, L., Canosa, N., Concheiro-Moscoso, P., Miranda-Duro, M. D. C., & Pereira, J. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18094631 · Cited by 15
“Previous study results support the effectiveness of using technology in children with ASD for learning new skills [10].”
BackgroundResultYazdanian, H., Vakili, A., Soltani, A., Rekhne, Z. B., Zareii, S., & Zarifian, T. (2023) · International Journal of Developmental Disabilities · doi:10.1080/20473869.2023.2277604 · Cited by 16
“With the rapid progress of innovative technologies, along with the affinity of many autistic people toward them (Grynszpan et al .”
High-Functioning Autism and Virtual Reality Applications: A Scoping Review
Chiappini, M., Dei, C., Micheletti, E., Biffi, E., & Storm, F. A. (2024) · Applied Sciences · doi:10.3390/app14073132 · Cited by 15
Pérez-Vázquez, E., Lorenzo, G., Carreres, A. L., & Lorenzo-Lledó, . (2019) · Technology Knowledge and Learning · doi:10.1007/s10758-019-09415-8 · Cited by 18
Lim, H. A., Ellis, E. M., & Sonnenschein, D. (2022) · Child Language Teaching and Therapy · doi:10.1177/02656590221080308 · Cited by 15
“Innovations are emerging in the efforts to improve outcomes for these socio-communicative deficits, including computerized and gamified interventions (Grynszpan et al., 2014; Zakari et al., 2014), providing extensive player/patient engagement and a channel for delivering measurable health-related changes (Baranowski e…”
BackgroundWesterberg, B., Bäärnhielm, S., Giles, C. J., Hylén, U., Holländare, F., & Bejerot, S. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.789663 · Cited by 16
Metadata
- Authors
- Grynszpan, O., Weiss, P. L. (., Perez-Diaz, F., & Gal, E.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- University of Haifa (IL)
- CNRS USR 3246, France
- Venue
- Autism
- Publisher
- SAGE Publications
- Published
- 2013-10-03
- Volume
- 18
- Issue
- 4
- Pages
- 346-361
- ISSN
- 1362-3613 (ISSN-L)
- 1461-7005
- OpenAlex
- W2165069154
- Cited by
- 621
- References
- 98
- Citations by year
- 2026: 112 · 2025: 37 · 2024: 44 · 2023: 65 · 2022: 41 · 2021: 61 · 2020: 61 · 2019: 49 · 2018: 54 · 2017: 43 · 2016: 26 · 2015: 16 · 2014: 8 · 2013: 4
- FWCI
- 1.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Autism (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Developmental and Educational Psychology › Behavioral and Psychological Studies
- Social Sciences › Psychology › Social Psychology › Social Robot Interaction and HRI
- Keywords
- autism spectrum disorder, technology-based interventions, computer-based training, virtual reality, interactive DVD, children, intervention effectiveness, intervention duration
- MeSH terms
- Child, Child Development Disorders, Pervasive, Female, Humans, Male, Patient Education as Topic, Robotics, Technology, Therapy, Computer-Assisted, Therapies, Investigational, Virtual Reality Exposure Therapy
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