The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Stem Cell Properties of Human Dental Pulp Stem Cells
Abstract
In this study, we characterized the self-renewal capability, multi-lineage differentiation capacity, and clonogenic efficiency of human dental pulp stem cells (DPSCs). DPSCs were capable of forming ectopic dentin and associated pulp tissue in vivo. Stromal-like cells were reestablished in culture from primary DPSC transplants and re-transplanted into immunocompromised mice to generate a dentin-pulp-like tissue, demonstrating their self-renewal capability. DPSCs were also found to be capable of differentiating into adipocytes and neural-like cells. The odontogenic potential of 12 individual single-colony-derived DPSC strains was determined. Two-thirds of the single-colony-derived DPSC strains generated abundant ectopic dentin in vivo, while only a limited amount of dentin was detected in the remaining one-third. These results indicate that single-colony-derived DPSC strains differ from each other with respect to their rate of odontogenesis. Taken together, these results demonstrate that DPSCs possess stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues
Prockop, D. J. (1997) · Science · doi:10.1126/science.276.5309.71 · Cited by 4,629
Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo
Gronthos, S., Mankani, M., Brahim, J., Robey, P. G., & Shi, S. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.240309797 · Cited by 4,570
Self-citationBone Marrow Stromal Stem Cells: Nature, Biology, and Potential Applications
Bianco, P., Riminucci, M., Gronthos, S., & Robey, P. G. (2001) · STEM CELLS · doi:10.1634/stemcells.19-3-180 · Cited by 1,939
Self-citationIsolation of multipotent adult stem cells from the dermis of mammalian skin
Toma, J. G., Akhavan, M., Fernandes, K. J. L., Barnabé-Heider, F., Sadikot, A., Kaplan, D. R., & Miller, F. D. (2001) · Nature Cell Biology · doi:10.1038/ncb0901-778 · Cited by 1,593
The Evolving Concept of a Stem Cell
Blau, H. M., Brazelton, T. R., & Weimann, J. M. (2001) · Cell · doi:10.1016/s0092-8674(01)00409-3 · Cited by 1,046
Azizi, S. A., Stokes, D., Augelli, B. J., DiGirolamo, C., & Prockop, D. J. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.7.3908 · Cited by 909
Fuchs, E., & Segre, J. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81691-8 · Cited by 764
Kuznetsov, S. A., Krebsbach, P. H., Satomura, K., Kerr, J., Riminucci, M., Benayahu, D., & Robey, P. G. (1997) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1997.12.9.1335 · Cited by 723
Self-citationHarada, H., Kettunen, P., Jung, H.-S., Mustonen, T., Wang, Y. A., & Thesleff, I. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.147.1.105 · Cited by 517
Krebsbach, P. H., Kuznetsov, S. A., Satomura, K., Emmons, R. V. B., Rowe, D. W., & Robey, P. G. (1997) · Transplantation · doi:10.1097/00007890-199704270-00003 · Cited by 481
Self-citation
Cited by
Viswanathan, S., Shi, Y., Galipeau, J., Krampera, M., Leblanc, K., Martin, I., Nolta, J., Phinney, D. G., & Sensebe, L. (2019) · Cytotherapy · doi:10.1016/j.jcyt.2019.08.002 · Cited by 839
Dental Pulp Tissue Engineering with Stem Cells from Exfoliated Deciduous Teeth
Cordeiro, M. M., Dong, Z., Kaneko, T., Zhang, Z., Miyazawa, M., Shi, S., Smith, A. J., & Nör, J. E. (2008) · Journal of Endodontics · doi:10.1016/j.joen.2008.04.009 · Cited by 668
Self-citationBessa, P. C., Casal, M., & Reis, R. L. (2008) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.74 · Cited by 549
The Application of Tissue Engineering to Regeneration of Pulp and Dentin in Endodontics
Nakashima, M., & Akamine, A. (2005) · Journal of Endodontics · doi:10.1097/01.don.0000164138.49923.e5 · Cited by 435
Isolation and characterization of multipotent human periodontal ligament stem cells
Gay, I., Chen, S., & MacDougall, M. (2007) · Orthodontics & Craniofacial Research · doi:10.1111/j.1601-6343.2007.00399.x · Cited by 420
Metadata
- Authors
- Gronthos, S., Brahim, J., Li, W., Fisher, L. W., Cherman, N., Boyde, A., DenBesten, P., Robey, P. G., & Shi, S.
- Venue
- Journal of Dental Research
- Publisher
- SAGE Publications
- Published
- 2002-08
- Volume
- 81
- Issue
- 8
- Pages
- 531-535
- ISSN
- 0022-0345 (ISSN-L)
- 1544-0591
- OpenAlex
- W2136767600
- Cited by
- 2,112
- References
- 20
- FWCI
- 10.08
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Stem Cell Properties of Human Dental Pulp Stem Cells. https://app.cochat.ai/papers/10.1177/154405910208100806
- The paper
- Gronthos, S., Brahim, J., Li, W., Fisher, L. W., Cherman, N., Boyde, A., DenBesten, P., Robey, P. G., & Shi, S. (2002). Stem Cell Properties of Human Dental Pulp Stem Cells. Journal of Dental Research. https://doi.org/10.1177/154405910208100806
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
