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Cited by 416

The DOI matches its Crossref record; 109 of the 109 references it cites were found in a registry or an index.

The Epidemiology and Risk Factors of Head and Neck Cancer: a Focus on Human Papillomavirus

Ragin, C.C.R., Modugno, F., Gollin, S.M.·2007·Journal of Dental Research

Abstract

Head and neck cancer was the eighth leading cause of cancer death worldwide in 2000. Although the incidence of head and neck squamous cell carcinoma (HNSCC) in the United States is relatively low, survival is poor and has not improved for several decades. While tobacco and alcohol are the primary risk factors for HNSCC development, epidemiological studies report a strong association with human papillomavirus (HPV) in a subset of HNSCC. More than 95% of cervical squamous cell carcinomas are linked to persistent HPV infection; evidence demonstrates that HPV is a necessary carcinogen. Not all HPV-positive HNSCC express the viral oncogenes ( E6 and E7), which suggests that HPV may function as a carcinogen in a smaller proportion of HNSCC. This review presents our current understanding of the relationship between HPV and HNSCC, and describes future research directions that may lead to a better understanding of the involvement of HPV in head and neck cancer.

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Metadata

Authors
Ragin, C. C. R., Modugno, F., & Gollin, S. M.
Venue
Journal of Dental Research
Published
2007-02
Volume
86
Issue
2
Pages
104-114
ISSN
  • 0022-0345 (ISSN-L)
  • 1544-0591
OpenAlex
W1982019987
Cited by
416
References
109
FWCI
26.79
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Epidemiology and Risk Factors of Head and Neck Cancer: a Focus on Human Papillomavirus. https://app.cochat.ai/papers/10.1177/154405910708600202
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Ragin, C. C. R., Modugno, F., & Gollin, S. M. (2007). The Epidemiology and Risk Factors of Head and Neck Cancer: a Focus on Human Papillomavirus. Journal of Dental Research. https://doi.org/10.1177/154405910708600202

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.