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Platelet and Lymphocyte-Related Parameters as Potential Markers of Osteoarthritis Severity: A Cross-Sectional Study

Salamanna, F., Pagani, S., Filardo, G., Contartese, D., Boffa, A., Angelelli, L., Maglio, M., Fini, M., Zaffagnini, S., & Giavaresi, G. (2024) · Biomedicines · doi:10.3390/biomedicines12092052 · Cited by 1 · see citing works

Exploring Trends and Gaps in Osteoarthritis Biomarker Research (1999-2024): A Citation Analysis of Top 50 Cited Articles

Hu, W., Yang, J., Liu, L., Li, D., Zhao, Y., & Wang, A. (2024) · Cartilage · doi:10.1177/19476035241288660 · Cited by 1 · see citing works

Diagnostic value of synovial calprotectin (S100A8/A9) in differential diagnosis of juvenile idiopathic arthritis and pigmented villonodular synovitis in children: preliminary results of a single-center study

Kozhevnikov, A. N., Derkach, E. A., Porohova, A. A., & Lukyanov, S. A. (2025) · Pediatric Traumatology Orthopaedics and Reconstructive Surgery · doi:10.17816/ptors635368 · Cited by 1 · see citing works

Tribocorrosion Behavior of Squid Pen‐Reinforced HDPE Biocomposites Against Ti6Al4V in Bovine Serum: Wear Mechanisms and Electrochemical Interactions

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The Design and Development of a Dexamethasone‐Tranfersome‐PF‐127/HA Stimuli‐Responsive Hydrogel for Intra‐Articular Therapy in Osteoarthritis

Motaung, A., Rants’o, T. A., Badhe, R. V., Somandi, K., & Choonara, Y. E. (2025) · Nano Select · doi:10.1002/nano.70047 · Cited by 1 · see citing works

Prevention and treatment of knee osteoarthritis by natural products: potential mechanisms based on articular cartilage targets

Ye, Q., Zhou, K., Gao, Q., Li, C., Sheng, Y., Zou, L., Tong, C., & Shou, D. (2026) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(26)61097-7 · Cited by 1 · see citing works

Synovial Fluid Proteomic Biomarkers in Knee Osteoarthritis: A Systematic Review and Gene Ontology Analysis

Parrotta, E. I., Benedetto, G. L., Cuda, G., Covello, R., Longo, U. G., Carnevale, A., Galasso, O., Gasparini, G., & Mercurio, M. (2026) · Cartilage · doi:10.1177/19476035261446251 · Cited by 1 · see citing works

Next-Generation Human Biofluid Diagnostics Enabled by AI-Integrated SERS Biosensors

Heo, B. Y., Huh, Y., Lee, S., Park, R., & Jung, H. S. (2026) · BioChip Journal · doi:10.1007/s13206-026-00277-8 · Cited by 1 · see citing works

Osteopontin in rheumatic diseases: A systematic review and meta-analysis

Zoroddu, S., Lorenzo, B. D., Paliogiannis, P., Mangoni, A. A., Carru, C., & Zinellu, A. (2025) · Clinica Chimica Acta · doi:10.1016/j.cca.2025.120209 · Cited by 1 · see citing works

Leptin reduces autophagy and improves the survival of human chondrocytes induced by inflammation through the mTOR signaling pathwayPreprint

Li, P., Li, J., Yang, Q., Lu, Y., & Zhang, J. (2023) · Research Square · doi:10.21203/rs.3.rs-2576503/v1

MALPOSITION OF THE TIBIAL COMPONENT IN PRIMARY KNEE ENDOPROSTHETICS AND ITS PREVENTION

Ivanov, E. A., Сергеевич, Б. В., Gurazhev, S. M., & Pavlov, V. V. (2023) · Современные проблемы науки и образования · doi:10.17513/spno.32922

Cartilage Oligomeric Matrix Protein (COMP) As a Candidate Biomarker in Osteoarthritis

Baygutalp, F., & Duysak, L. (2023) · Özgür Yayınları eBooks · doi:10.58830/ozgur.pub305.c1246

Diagnostic indications of knee joint fluid – current state ofknowledge

Turzański, D. (2023) · Diagnostyka Laboratoryjna · doi:10.5604/01.3001.0054.1912

Biomarkers in cartilage repair and osteoarthritis

Haartmans, M. J. J. (2024) · doi:10.26481/dis.20240220mh

MCP-1 in synovial fluid as a predictor of inferior clinical outcomes after meniscectomy

Wolfe, I. A., Egol, A. J., Moore, M. R., Isber, R., Kaplan, D. J., Kirsch, T., & Strauss, E. J. (2024) · The Knee · doi:10.1016/j.knee.2024.09.002

Synovial Joint Fluid Omics Researches in Osteoarthritis: An Affinity Chromatography-Based Perspective

Aladağ, S., Demirdiş, İ., Gökçal, B., Fidan, B. B., Aktaş, B. E., Gizer, M., Kaplan, O., Yet, İ., Ekiz, M. Ş., Korkusuz, P., et al. (2025) · Tissue repair and reconstruction · doi:10.1007/978-981-96-3808-6_3

Novel biomaterial-based synovial fluid analysis reveals protective microRNA signatures in a mouse model of acute synovitis-driven osteoarthritisPreprint

Takahata, K., Arakawa, K., Yasuda, T., Enomoto, S., Katashima, T., Sakai, T., & Kokubun, T. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.11.675532

Diagnostic and prognostic potential of biomarkers in femoroacetabular impingement syndrome: A systematic review

Yoshitani, J., Ekhtiari, S., Dulleston, J., Malviya, A., & Khanduja, V. (2025) · Journal of Experimental Orthopaedics · doi:10.1002/jeo2.70417

GENDER- AND AGE-RELATED FEATURES OF SYNOVIAL MEMBRANE MORPHOLOGICAL CHANGES IN TRAUMATIC KNEE INJURIES IN PATIENTS WITH METABOLIC COMORBIDITY

Boskina, M. H. (2025) · Kharkiv Surgical School · doi:10.37699/2308-7005.5.2025.15

Identification and functional analysis of hub genes in knee osteoarthritis via bioinformatics and experimental validation

Jiang, S., Cao, J., Lu, J., Liang, J., Li, L., Song, Y., Gao, J., & Jiang, B. (2025) · Frontiers in Bioinformatics · doi:10.3389/fbinf.2025.1671693

Synovial Parasitosis and Inflammatory Biomarker Profiles in Osteoarthritis: Associations with Host and Therapeutic Factors

Hassanein, F., Shehata, A. I., Aldawoudy, A. M., & Masoud, I. M. (2025) · Acta Parasitologica · doi:10.1007/s11686-025-01180-2

Non-Imaging Differential Diagnosis of Lower Limb Osteoarthritis: An Interpretable Machine Learning Framework

Baigarayeva, Z., Boltaboyeva, A., Иманбек, Б., Amangeldy, B., Tasmurzayev, N., Ozhikenov, К., Ozhiken, A. K., Alimbayeva, Z. N., & Nishino, N. (2026) · Algorithms · doi:10.3390/a19010087

Establishment of a Prediction Model to Diagnose the End-stage Knee Osteoarthritis Based on a Significant Difference in Ferroptosis-Related Genes in Chondrocytes

Min, L., Chen, C., & Wang, W. (2026) · Zeitschrift für Orthopädie und Unfallchirurgie · doi:10.1055/a-2762-1558

Exercise-myokine relationships in osteoarthritis

Zhang, Y., Pan, C., Hou, W., Sun, K., & Xu, T. (2026) · Journal of Translational Medicine · doi:10.1186/s12967-026-08080-7

Synovial Fluid Biomarkers Reflect Pre‐ and Postoperative Clinical Features in Rotator Cuff Tears, Independent of Tear Size

Jeong, S., Lee, J. M., Koh, J., & Lee, D. (2026) · Journal of Orthopaedic Research® · doi:10.1002/jor.70235

Defining the Impact of Genetics on Equine Performance and Development of Orthopaedic Disease

Chernavsky, H., Pezzanite, L. M., Simske, S., & Kawcak, C. E. (2026) · Animals · doi:10.3390/ani16121875

Novel Biomaterial‐Based Synovial Fluid Analysis Reveals Protective microRNA Signatures in a Mouse Model of Acute Synovitis‐Driven Osteoarthritis

Takahata, K., Arakawa, K., Yasuda, T., Enomoto, S., Katashima, T., Sakai, T., & Kokubun, T. (2026) · The FASEB Journal · doi:10.1096/fj.202505006r

Synovial fluid IL-16 and RANTES/CCL5 signals in early knee osteoarthritis: a pilot antibody-array study

Lin, B., Wu, B., Chen, H., Lin, W., Lin, D., & Feng, E. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1889340

Orthobiologics at a Crossroads: From Biological Promise to Evidence-Based Orthopaedic Practice

Anzillotti, G., Conte, P., Dragoo, J. L., & Kon, E. (2026) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.26.00684

Long-term efficacy and safety of intra-articular corticosteroid injections in patients with knee osteoarthritis

Thirumaran, A. J., & Hunter, D. J. (2026) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2026.2707152

Safety and preliminary efficacy of allogeneic bone marrow-derived mesenchymal stromal cells (BMSC) for painful lumbar facet arthropathy: study protocol for a randomised, double-blinded, placebo-controlled, crossover phase II clinical trial

Yan, D., Durand, N., Wang, Z., Osborne, M. D., Stone, J., Gupta, S., Miller, D. A., Witter, D. M., Eldrige, J. S., Quiñones‐Hinojosa, A., et al. (2026) · BMJ Open · doi:10.1136/bmjopen-2025-113509

The diagnostic value and pathological application of TREM2 in patients with osteoarthritis

Bao, H., Wei, W., Xu, C., Huang, Y., Zhang, W., & Ma, J. J. (2026) · Clinical Rheumatology · doi:10.1007/s10067-026-08316-3

Consensus Recommendations for Common Data Elements in Osteoarthritis and Posttraumatic Osteoarthritis Research From the ATOAC: Part III—Imaging and Biomarkers

Torp, D. M. (2026) · Journal of Applied Biomechanics · doi:10.1123/jab.2025-0131

Immune dysregulation in osteoarthritis: Mechanisms, biomarkers, and therapeutic opportunities

Enteshari-Moghaddam, A., Khorramdelazad, H., & Abbasifard, M. (2026) · Journal of Translational Autoimmunity · doi:10.1016/j.jtauto.2026.100395

Evaluation of the Suitability of Xylosyltransferase Activity in Serum and Synovial Fluid as a Biomarker for Arthrofibrosis

Huang, Y., Jagodzinski, M., Faust, I., Traut, P., Hennecke, T., & Krenn, V. (2026) · Journal of Orthopaedics · doi:10.25259/joo_110_2026

Preparing the soil in knee osteoarthritis: a seed–systemic soil–local tissue soil framework for orthobiologic response heterogeneity

Batista, J. D., Batista, J. D., Batista, J. D., Pereira, G. S., & Silva, M. (2026) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2026.1946746

Focus on the NLRP3 inflammasome: its role in the pathogenesis and therapeutic potential of inflammation-driven osteoarthritis

Li, F., Tan, M., Zhai, R., Ouyang, Y., & Shen, H. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1938807 · Cited by 1 · see citing works

Plant-Derived Polyphenols in Osteoarthritis: Mechanisms, Delivery Systems, and Therapeutic Synergy

Farhan, M. (2026) · Life · doi:10.3390/life16101653

Synovial Fluid Biomarkers: Current Applications and Future Perspectives

Terzieva, V., Ivanova, M. G., & Kotov, G. N. (2026) · Rheumatology (Bulgaria) · doi:10.35465/6rdws549

Combination of Synovial Fluid Biomarkers Enables Accurate Detection of Early Knee Osteoarthritis

Hlubek, R., Kušnierová, P., Všianský, F., Walder, P., Bystronova, I., & Douša, P. (2026) · Bratislavské lekárske listy/Bratislava medical journal · doi:10.1007/s44411-026-00886-7

The role of the cGAS-STING-mediated inflammatory amplification loop in osteoarthritis: from danger-associated DNA sensing to whole-joint remodeling and precision therapy

Yang, X., Zhang, L., Yu, Y., 吴术红, & Yang, L. (2026) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2026.1995231

Synovial fluid biomarkers associated with osteoarthritis severity reflect macrophage and neutrophil related inflammation

Haraden, C. A., Huebner, J. L., Hsueh, M.-F., Li, Y., & Kraus, V. B. (2019) · Arthritis Research & Therapy · doi:10.1186/s13075-019-1923-x · Cited by 196 · see citing works

Integrated proteomics–driven discovery of synovial fluid biomarkers reflecting structural damage and pain in knee osteoarthritis

Gil, T., Cho, H. C., Jang, D. S., Kim, J. E., Shin, J.-W., Han, S., Kraus, V. B., Li, Y., Jang, K.-M., & Jeon, O. H. (2026) · Scientific Reports · doi:10.1038/s41598-026-63579-9

Combination of Synovial Fluid Biomarkers Enables Accurate Detection of Early Knee Osteoarthritis

Hlubek, R., Kušnierová, P., Všianský, F., Walder, P., Bystronova, I., & Douša, P. (2026) · Bratislavské lekárske listy/Bratislava medical journal · doi:10.1007/s44411-026-00886-7

Identification of Synovial Fluid Biomarkers for Knee Osteoarthritis and Correlation with Radiographic Assessment

Monibi, F., Roller, B. L., Stoker, A. M., Garner, B. C., Bal, B. S., & Cook, J. L. (2015) · The Journal of Knee Surgery · doi:10.1055/s-0035-1549022 · Cited by 76 · see citing works

Osteoarthritis year 2013 in review: biomarkers; reflecting before moving forward, one step at a time

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