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Cited by 31Probiotics and Fermented FoodsNeutropenia and Cancer InfectionsInfective Endocarditis Diagnosis and Management

Recurrent Lactobacillus Bacteremia in a Patient With Leukemia

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Ambesh, Paurush, Stroud, Sarah, Franzova, Eva, Gotesman, Joseph, Sharma, Kavita, Wolf, Lawrence, Kamholz, Stephan·2017·Journal of Investigative Medicine High Impact Case Reports
DOI 10.1177/2324709617744233PMC PMC5703097
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Abstract

Lactobacillus species are a commensal flora of the human gastrointestinal and the female genitourinary tract. Lactobacilli especially the rhamnosus species, are common components of commercial probiotics. They are rarely associated with pathology in immunocompetent people, but they have been known to cause dental caries, bacteremia, and endocarditis in patients with suppressed immune function. Cases of Lactobacillus bacteremia have been reported in patients with acute myeloid leukemia, large granular lymphocytic leukemia, and in transplant recipients. In this article, we report a strange case of recurrent Lactobacillus bacteremia causing multiple episodes of fever of unknown origin in a patient with leukemia. This report is unique as Lactobacillus is not recognized as a common source of bacteremia. Moreover, the source of the bacillus continued to elude us even after extensive investigation.

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  • Our review revealed 49 case reports of LB without any history of probiotic use.

    “Our review also revealed 49 case reports of LB without any history of probiotic use (Table 1) [24,26,27,33,35,45,46,47,48,49,50,51].”

    From Lactobacillus Bacteremia and Probiotics: A Review (2023) · cites this paper as [46]

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Research works printed but not linked: 14

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Cited by

Sorted by citations

Authors
Ambesh, P., Stroud, S., Franzova, E., Gotesman, J., Sharma, K., Wolf, L., & Kamholz, S.
Affiliations
Maimonides Medical Center (US)
Corresponding author
Ambesh, Paurush
ORCID
Venue
Journal of Investigative Medicine High Impact Case Reports
Publisher
SAGE Publications
Published
2017-10
Volume
5
Issue
4
Pages
2324709617744233-2324709617744233
ISSN
2324-7096 (ISSN-L)
DOI
10.1177/2324709617744233
PMC
PMC5703097
OpenAlex
W2769847105
Cited by
31
References
6
Citations by year
2026: 5 · 2025: 4 · 2023: 6 · 2022: 4 · 2021: 6 · 2020: 4 · 2019: 1 · 2018: 1
FWCI
1.85
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Investigative Medicine High Impact Case Reports (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Health Sciences › Medicine › Oncology › Neutropenia and Cancer Infections
  • Health Sciences › Medicine › Epidemiology › Infective Endocarditis Diagnosis and Management
Keywords
recurrent bacteremia, leukemia, fever of unknown origin, immunocompromised patients, Lactobacillus rhamnosus, probiotics, opportunistic infections

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