The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
MicroRNAs modulate the angiogenic properties of HUVECs
Open accessAbstract
MicroRNAs (miRNAs) have recently come into focus as key posttranscriptional modulators of gene expression. In this work, we addressed whether in vitro angiogenesis is an miRNA-regulated process. We performed large-scale analysis of miRNA expression in human umbilical vein endothelial cells (HUVECs) and found that 15 highly expressed miRNAs have the receptors of angiogenic factors as putative targets. In particular, we demonstrated that miR-221 and miR-222 affect c-Kit expression and, as a consequence, the angiogenic properties of its ligand stem cell factor. Interaction between miR-222 and c-Kit is likely to be part of a complex circuit that controls the ability of endothelial cells to form new capillaries.
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Cites
Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714
Prediction of Mammalian MicroRNA Targets
Lewis, B. P., Shih, I.-H., Jones-Rhoades, M. W., Bartel, D. P., & Burge, C. B. (2003) · Cell · doi:10.1016/s0092-8674(03)01018-3 · Cited by 5,199
Combinatorial microRNA target predictions
Krek, A., Grün, D., Poy, M. N., Wolf, R., Rosenberg, L., Epstein, E. J., MacMenamin, P., da Piedade, I., Gunsalus, K. C., Stoffel, M., et al. (2005) · Nature Genetics · doi:10.1038/ng1536 · Cited by 4,603
BASKERVILLE, S., & BARTEL, D. P. (2005) · RNA · doi:10.1261/rna.7240905 · Cited by 1,508
Cited by
miR-126 Regulates Angiogenic Signaling and Vascular Integrity
Fish, J. E., Santoro, M. M., Morton, S. U., Yu, S., Yeh, R.-F., Wythe, J. D., Ivey, K. N., Bruneau, B. G., Stainier, D. Y. R., & Srivastava, D. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.07.008 · Cited by 1,515
Bloomston, M., Frankel, W. L., Petrocca, F., Volinia, S., Alder, H., Hagan, J. P., Liu, C.-G., Bhatt, D., Taccioli, C., & Croce, C. M. (2007) · JAMA · doi:10.1001/jama.297.17.1901 · Cited by 1,141
Role of microRNAs in vascular diseases, inflammation, and angiogenesis
Urbich, C., Kuehbacher, A., & Dimmeler, S. (2008) · Cardiovascular Research · doi:10.1093/cvr/cvn156 · Cited by 880
Role of Dicer and Drosha for Endothelial MicroRNA Expression and Angiogenesis
Kuehbacher, A., Urbich, C., Zeiher, A. M., & Dimmeler, S. (2007) · Circulation Research · doi:10.1161/circresaha.107.153916 · Cited by 786
Dicer Dependent MicroRNAs Regulate Gene Expression and Functions in Human Endothelial Cells
Suárez, Y., Fernández-Hernando, C., Pober, J. S., & Sessa, W. C. (2007) · Circulation Research · doi:10.1161/01.res.0000265065.26744.17 · Cited by 698
Metadata
- Authors
- Poliseno, L., Tuccoli, A., Mariani, L., Evangelista, M., Citti, L., Woods, K., Mercatanti, A., Hammond, S., & Rainaldi, G.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2006-11-01
- Volume
- 108
- Issue
- 9
- Pages
- 3068-3071
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W1968102833
- Cited by
- 754
- References
- 4
- FWCI
- 10.41
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Poliseno, L., Tuccoli, A., Mariani, L., Evangelista, M., Citti, L., Woods, K., Mercatanti, A., Hammond, S., & Rainaldi, G. (2006). MicroRNAs modulate the angiogenic properties of HUVECs. Blood. https://doi.org/10.1182/blood-2006-01-012369
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