The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention
Abstract
As the risks of allogeneic blood transfusion (ABT)–transmitted viruses were reduced to exceedingly low levels in the US, transfusion-related acute lung injury (TRALI), hemolytic transfusion reactions (HTRs), and transfusion-associated sepsis (TAS) emerged as the leading causes of ABT-related deaths. Since 2004, preventive measures for TRALI and TAS have been implemented, but their implementation remains incomplete. Infectious causes of ABT-related deaths currently account for less than 15% of all transfusion-related mortality, but the possibility remains that a new transfusion-transmitted agent causing a fatal infectious disease may emerge in the future. Aside from these established complications of ABT, randomized controlled trials comparing recipients of non–white blood cell (WBC)–reduced versus WBC-reduced blood components in cardiac surgery have documented increased mortality in association with the use of non-WBC–reduced ABT. ABT-related mortality can thus be further reduced by universally applying the policies of avoiding prospective donors alloimmunized to WBC antigens from donating plasma products, adopting strategies to prevent HTRs, WBC-reducing components transfused to patients undergoing cardiac surgery, reducing exposure to allogeneic donors through conservative transfusion guidelines and avoidance of product pooling, and implementing pathogen-reduction technologies to address the residual risk of TAS as well as the potential risk of the next transfusion-transmitted agent to emerge in the foreseeable future.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care
Hébert, P. C., Wells, G., Blajchman, M. A., Marshall, J., Martin, C., Pagliarello, G., Tweeddale, M., Schweitzer, I., & Yetisir, E. (1999) · New England Journal of Medicine · doi:10.1056/nejm199902113400601 · Cited by 5,187
Self-citationA Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care
(1999) · New England Journal of Medicine · doi:10.1056/nejm199904013401322 · Cited by 2,037
Infection with chikungunya virus in Italy: an outbreak in a temperate region
Rezza, G., Nicoletti, L., Angelini, R., Romi, R., Finarelli, A., Panning, M., Cordioli, P., Fortuna, C., Boros, S., Magurano, F., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61779-6 · Cited by 1,527
Duration of Red-Cell Storage and Complications after Cardiac Surgery
Koch, C. G., Li, L., Sessler, D. I., Figueroa, P., Hoeltge, G. A., Mihaljevic, T., & Blackstone, E. H. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa070403 · Cited by 1,363
Diagnostic and pathogenetic considerations in transfusion‐related acute lung injury
Popovsky, M. A., & Moore, S. B. (1985) · Transfusion · doi:10.1046/j.1537-2995.1985.25686071434.x · Cited by 820
Reports of 355 transfusion‐associated deaths: 1976 through 1985
Sazama, K. (1990) · Transfusion · doi:10.1046/j.1537-2995.1990.30790385515.x · Cited by 729
Toward an understanding of transfusion‐related acute lung injury: statement of a consensus panel
Kleinman, S., Caulfield, T., Chan, P., Davenport, R., McFarland, J., McPhedran, S., Meade, M., Morrison, D., Pinsent, T., Robillard, P., et al. (2004) · Transfusion · doi:10.1111/j.0041-1132.2004.04347.x · Cited by 712
Transmission of West Nile Virus through Blood Transfusion in the United States in 2002
Pealer, L. N., Marfin, A. A., Petersen, L. R., Lanciotti, R. S., Page, P. L., Stramer, S. L., Stobierski, M. G., Signs, K., Newman, B., Kapoor, H., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030969 · Cited by 686
Transfusion-related immunomodulation (TRIM): An update
Vamvakas, E. C., & Blajchman, M. A. (2007) · Blood Reviews · doi:10.1016/j.blre.2007.07.003 · Cited by 664
Self-citationDodd, R. Y., Notari, E. P., & Stramer, S. L. (2002) · Transfusion · doi:10.1046/j.1537-2995.2002.00174.x · Cited by 643
Cited by
Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology
Kozek-Langenecker, S. A., Afshari, A., Albaladejo, P., Santullano, C. A. A., De Robertis, E., Filipescu, D. C., Fries, D., Görlinger, K., Haas, T., Imberger, G., et al. (2013) · European Journal of Anaesthesiology · doi:10.1097/eja.0b013e32835f4d5b · Cited by 909
Preoperative anaemia is associated with poor clinical outcome in non-cardiac surgery patients
Baron, D. M., Hochrieser, H., Posch, M., Metnitz, B., Rhodes, A., Moreno, R. P., Pearse, R. M., & Metnitz, P. (2014) · British Journal of Anaesthesia · doi:10.1093/bja/aeu098 · Cited by 431
Patient blood management in Europe
Shander, A., Van Aken, H., Colomina, M. J., Gombotz, H., Hofmann, A., Krauspe, R., Lasocki, S., Richards, T., Slappendel, R., & Spahn, D. R. (2012) · British Journal of Anaesthesia · doi:10.1093/bja/aes139 · Cited by 300
Shander, A., Fink, A., Javidroozi, M., Erhard, J., Farmer, S. L., Corwin, H., Goodnough, L. T., Hofmann, A., Isbister, J., Ozawa, S., et al. (2011) · Transfusion Medicine Reviews · doi:10.1016/j.tmrv.2011.02.001 · Cited by 216
Anaemia in inflammatory rheumatic diseases
Weiss, G., & Schett, G. (2013) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2012.183 · Cited by 146
Metadata
- Authors
- Vamvakas, E. C., & Blajchman, M. A.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2009-04-09
- Volume
- 113
- Issue
- 15
- Pages
- 3406-3417
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W2100222319
- Cited by
- 621
- References
- 47
- FWCI
- 25.79
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention. https://app.cochat.ai/papers/10.1182/blood-2008-10-167643
- The paper
- Vamvakas, E. C., & Blajchman, M. A. (2009). Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention. Blood. https://doi.org/10.1182/blood-2008-10-167643
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
