The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans
Open accessAbstract
Key Points: Life span estimates can be sensitive to the duration of stable isotope label administration, explaining discrepancies in the literature. Multiexponential models are needed to obtain reliable leukocyte life span estimates.
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In the citing paper
“Naive murine T cells survive for only 30 days, while cell divisions from homeostatic proliferation occur only every 1 to 2 years”
From Successful and Maladaptive T Cell Aging (2017) · cites this paper as Westera et al., 2013
In the citing paper
“memory T cell homeostasis is more dynamic than that of naive T cells with daily turnover rates of around 0.6%, shows evidence of a higher degree of population heterogeneity in stable isotope-labeling studies”
From Successful and Maladaptive T Cell Aging (2017) · cites this paper as Westera et al., 2013
Citations
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Self-citationDetermination of total body water by a simple and rapid mass spectrometric method
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Metadata
- Authors
- Westera, L., Drylewicz, J., den Braber, I., Mugwagwa, T., van der Maas, I., Kwast, L., Volman, T., van de Weg-Schrijver, E. H. R., Bartha, I., Spierenburg, G., Gaiser, K., Ackermans, M. T., Asquith, B., de Boer, R. J., Tesselaar, K., & Borghans, J. A. M.
- Affiliations
- University Medical Center Utrecht (NL)
- Utrecht University (NL)
- Laboratory for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands;
- Eötvös Loránd University (HU)
- Amsterdam UMC Location University of Amsterdam (NL)
- Imperial College London (GB)
- Theoretical Biology & Bioinformatics, Department of Biology, Utrecht University, Utrecht, The Netherlands;
- ORCID
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2013-09-26
- Volume
- 122
- Issue
- 13
- Pages
- 2205-2212
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W1976831998
- Cited by
- 136
- References
- 22
- Citations by year
- 2026: 7 · 2025: 12 · 2024: 9 · 2023: 10 · 2022: 12 · 2021: 17 · 2020: 15 · 2019: 10 · 2018: 13 · 2017: 12 · 2016: 6 · 2015: 10 · 2014: 2 · 2013: 1
- FWCI
- 3.50
- Type
- journal article
- Language
- en
- Open access
- green
- infoscience.epfl.ch
- Locations
- Blood (publishedVersion)
- PubMed (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion)
- Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion, cc-by-nc-nd)
- IRIS (submittedVersion)
- Pure Amsterdam UMC (submittedVersion)
- SERVAL (Université de Lausanne) (submittedVersion)
- Funders
- Medical Research Council (MR/J007439/1)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
- Life Sciences › Immunology and Microbiology › Immunology › Immunotoxicology and immune responses
- Keywords
- stable isotope labeling, single exponential model, mouse-to-human extrapolation
- MeSH terms
- Animals, Cell Separation, Humans, Isotope Labeling, Male, Mice, Inbred C57BL, Models, Theoretical, T-Lymphocytes, Deuterium Oxide, Mice
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