The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
Circulating cell membrane microparticles transfer heme to endothelial cells and trigger vasoocclusions in sickle cell disease
Open accessAbstract
Key Points: A significant fraction of cell-free heme in plasma is contained in circulating erythrocyte MPs, particularly during hemolysis. Heme-laden MPs can transfer heme to vascular endothelium and mediate oxidative stress, vascular dysfunction, and vasoocclusions.
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Citations
Cites
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease
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“MP heme might then target cell surface receptors, such as TLR-4 and trigger signaling pathways similar, in part, to those described for soluble heme, including ROS production.(25,26)”
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Cited by
Pathophysiology of Sickle Cell Disease
Sundd, P., Gladwin, M. T., & Novelli, E. M. (2019) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-012418-012838 · Cited by 813
Intravascular hemolysis and the pathophysiology of sickle cell disease
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Nader, E., Skinner, S., Romana, M., Fort, R., Lemonne, N., Guillot, N., Gauthier, A., Antoine-Jonville, S., Renoux, C., Hardy-Dessources, M.-D., et al. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01329 · Cited by 502
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Inflammation in sickle cell disease
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Metadata
- Authors
- Camus, S. M., De Moraes, J. A., Bonnin, P., Abbyad, P., Le Jeune, S., Lionnet, F., Loufrani, L., Grimaud, L., Lambry, J.-C., Charue, D., Kiger, L., Renard, J.-M., Larroque, C., Le Clésiau, H., Tedgui, A., Bruneval, P., Barja-Fidalgo, C., Alexandrou, A., Tharaux, P.-L., Boulanger, C. M., & Blanc-Brude, O. P.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2015-06-11
- Volume
- 125
- Issue
- 24
- Pages
- 3805-3814
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W2066856450
- Cited by
- 262
- References
- 51
- FWCI
- 14.67
- Type
- journal article
- Language
- en
- Open access
- green
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- The paper
- Camus, S. M., De Moraes, J. A., Bonnin, P., Abbyad, P., Le Jeune, S., Lionnet, F., Loufrani, L., Grimaud, L., Lambry, J.-C., Charue, D., Kiger, L., Renard, J.-M., Larroque, C., Le Clésiau, H., Tedgui, A., Bruneval, P., Barja-Fidalgo, C., Alexandrou, A., Tharaux, P.-L., . . . Blanc-Brude, O. P. (2015). Circulating cell membrane microparticles transfer heme to endothelial cells and trigger vasoocclusions in sickle cell disease. Blood. https://doi.org/10.1182/blood-2014-07-589283
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
