The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Hydrogen Peroxide Is Involved in Collagen-Induced Platelet Activation
Open accessAbstract
In this study, we investigated whether (1) collagen-induced platelet aggregation is associated with a burst of H2O2, (2) this oxidant species is involved in the activation of platelets, and (3) the pathways of platelet activation are stimulated by H2O2. Collagen-induced platelet aggregation was associated with production of H2O2, which was abolished by catalase, an enzyme that destroys H2O2. H2O2 production was not observed when ADP or thrombin were used as agonists. Catalase inhibited dose-dependently thromboxane A2 production, release of arachidonic acid from platelet membrane, and Inositol 1,4,5P3 (IP3) formation. In aspirin-treated platelets stimulated with high concentrations of collagen, catalase inhibited platelet aggregation, calcium mobilization, and IP3 production. This study suggests that collagen-induced platelet aggregation is associated with a burst of H2O2 that acts as a second messenger by stimulating the arachidonic acid metabolism and phospholipase C pathway.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cross, A. R., & Jones, O. T. G. (1986) · Biochemical Journal · doi:10.1042/bj2370111 · Cited by 551
Cited by
Role of Catalase in Oxidative Stress- and Age-Associated Degenerative Diseases
Nandi, A., Yan, L.-J., Jana, C. K., & Das, N. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/9613090 · Cited by 1,185
Olive tree (Olea europaea) leaves: potential beneficial effects on human health
El, S. N., & Karakaya, S. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.2009.00248.x · Cited by 466
Snake venom l-amino acid oxidases
Du, X.-Y., & Clemetson, K. J. (2002) · Toxicon · doi:10.1016/s0041-0101(02)00102-2 · Cited by 413
Redox signals in wound healing
Sen, C. K., & Roy, S. (2008) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2008.01.006 · Cited by 349
Pignatelli, P., Pulcinelli, F. M., Celestini, A., Lenti, L., Ghiselli, A., Gazzaniga, P. P., & Violi, F. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.5.1150 · Cited by 275
Self-citation
Metadata
- Authors
- Pignatelli, P., Pulcinelli, F. M., Lenti, L., Paolo Gazzaniga, P., & Violi, F.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 1998-01-15
- Volume
- 91
- Issue
- 2
- Pages
- 484-490
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W1547926186
- Cited by
- 324
- References
- 1
- FWCI
- 4.67
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Hydrogen Peroxide Is Involved in Collagen-Induced Platelet Activation. https://app.cochat.ai/papers/10.1182/blood.v91.2.484
- The paper
- Pignatelli, P., Pulcinelli, F. M., Lenti, L., Paolo Gazzaniga, P., & Violi, F. (1998). Hydrogen Peroxide Is Involved in Collagen-Induced Platelet Activation. Blood. https://doi.org/10.1182/blood.v91.2.484
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
