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NADPH Oxidase: An Update

Babior, Bernard M.·1999·Blood

Abstract

T HE NADPH OXIDASES are a group of plasma membrane–associated enzymes found in a variety of cells of mesodermal origin. The most thoroughly studied of these is the leukocyte NADPH oxidase, which is found in professional phagocytes and B lymphocytes. It catalyzes the production of superoxide (O2

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  1. Wallach, 1996, Stoichiometry of the subunits of flavocytochrome b558 of the NADPH oxidase of phagocytes., Biochem J, 320, 33, 10.1042/bj3200033 · DOI
  2. Nisimoto, 1995, Reconstitution of flavin-depleted neutrophil flavocytochrome b558 with 8-mercapto-FAD and characterization of the flavin-reconstituted enzyme., J Biol Chem, 270, 16428, 10.1074/jbc.270.27.16428 · DOI
  3. Cross, 1995, Cytochrome b245 of the neutrophil superoxide-generating system contains two nonidentical hemes. Potentiometric studies of a mutant form of gp91phox., J Biol Chem, 270, 17075, 10.1074/jbc.270.29.17075 · DOI
  4. Koshkin, 1997, Electron transfer in the superoxide-generating NADPH oxidase complex reconstituted in vitro., Biochim Biophys Acta Bio-Energetics, 1319, 139, 10.1016/S0005-2728(96)00154-5 · DOI
  5. Woodman, 1991, The respiratory burst oxidase and three of four oxidase-related polypeptides are associated with the cytoskeleton of human neutrophils., J Clin Invest, 87, 1345, 10.1172/JCI115138 · DOI
  6. Foroozan, 1992, The reduction of cytochrome b558 and the activity of the respiratory burst oxidase from human neutrophils., J Biol Chem, 267, 24400, 10.1016/S0021-9258(18)35780-6 · doi:10.1016/s0021-9258(18)35780-6
  7. Cross, 1985, Mechanism of the superoxide-producing oxidase of neutrophils. O2 is necessary for the fast reduction of cytochrome b-245 by NADPH., Biochem J, 226, 881, 10.1042/bj2260881 · DOI
  8. Cross, 1982, The enzymic reduction and kinetics of oxidation of cytochrome b-245 of neutrophils., Biochem J, 204, 479, 10.1042/bj2040479 · DOI
  9. Gabig, 1982, Functional relationship of the cytochrome b to the superoxide-generating oxidase of human neutrophils., J Biol Chem, 257, 4114, 10.1016/S0021-9258(18)34693-3 · DOI
  10. Doussiere, 1996, Electron transfer across the O2−-generating flavocytochrome b of neutrophils. Evidence for a transition from a low-spin state to a high-spin state of the heme iron component., J Biol Chem, 270, 17075
  11. Babior, 1981, The O2−-producing enzyme of human neutrophils: Further properties., J Biol Chem, 256, 2321, 10.1016/S0021-9258(19)69781-4 · DOI
  12. Light, 1981, Characteristics of the cofactor requirements for the superoxide-generating NADPH oxidase of human polymorphonuclear leukocytes., Biochemistry, 20, 1468, 10.1021/bi00509a010 · DOI · Paper page
  13. Robertson, 1990, The use of diphenylene iodonium, an inhibitor of NADPH oxidase, to investigate the antimicrobial action of human monocyte derived macrophages., J Immunol Methods, 133, 175, 10.1016/0022-1759(90)90357-2 · DOI
  14. Babior, 1992, The respiratory burst oxidase., Adv Enzymol, 65, 49
  15. Koshkin, 1994, Superoxide production by cytochrome b559. Mechanism of cytosol-independent activation., FEBS Lett, 338, 285, 10.1016/0014-5793(94)80285-8 · DOI
  16. Koshkin, 1993, Generation of superoxide by purified and relipidated cytochrome b559 in the absence of cytosolic activators., FEBS Lett, 327, 57, 10.1016/0014-5793(93)81039-3 · DOI
  17. Green, 1986, The NADPH:O2 oxidoreductase of human neutrophils., J Biol Chem, 261, 6010, 10.1016/S0021-9258(17)38486-7 · DOI
  18. Cross, 1994, The superoxide-generating system of human neutrophils possesses a novel diaphorase activity. Evidence for distinct regulation of electron flow within NADPH oxidase by p67-phox and p47-phox., J Biol Chem, 269, 21448, 10.1016/S0021-9258(17)31824-0 · DOI
  19. Li, 1997, Purified leukocyte cytochrome b558 incorporated into liposomes catalyzes a cytosolic factor dependent diaphorase activity., Biochemistry, 36, 5529, 10.1021/bi963013r · doi:10.1021/bi963013r
  20. Ariga, 1993, A newly recognized point mutation in the cytochrome b558 heavy chain gene replacing alanine57 by glutamic acid, in a patient with cytochrome b positive X-linked chronic granulomatous disease., Eur J Pediatr, 152, 469, 10.1007/BF01955051 · DOI
  21. Rae, 1998, X-Linked chronic granulomatous disease: mutations in the CYBB gene encoding the gp91-phox component of respiratory-burst oxidase., Am J Hum Genet, 62, 1320, 10.1086/301874 · DOI
  22. Jendrossek, 1997, An in-frame triplet deletion within the gp91-phox gene in an adult X-linked chronic granulomatous disease patient with residual NADPH-oxidase activity., Eur J Haematol, 58, 78, 10.1111/j.1600-0609.1997.tb00928.x · DOI
  23. Heyworth, 1991, Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558., J Clin Invest, 87, 352, 10.1172/JCI114993 · DOI · Paper page
  24. Freeman, 1996, Rac “insert region” is a novel effector region that is implicated in the activation of NADPH oxidase, but not PAK65., J Biol Chem, 271, 19794, 10.1074/jbc.271.33.19794 · DOI
  25. Koshkin, 1996, The cytosolic component p47phox is not a sine qua non participant in the activation of NADPH oxidase but is required for optimal superoxide production., J Biol Chem, 271, 30326, 10.1074/jbc.271.48.30326 · DOI
  26. Cross, 1995, The cytosolic activating factor p47phox and p67phox have distinct roles in the regulation of electron flow in NADPH oxidase., J Biol Chem, 270, 6543, 10.1074/jbc.270.12.6543 · DOI
  27. Smith, 1996, The cytosolic subunit p67phox contains an NADPH-binding site that participates in catalysis by the leukocyte NADPH oxidase., J Clin Invest, 98, 977, 10.1172/JCI118882 · DOI
  28. Doussiere, 1993, Critical assessment of the presence of an NADPH binding site on neutrophil cytochrome b558 by photoaffinity and immunochemical labeling., Biochemistry, 32, 8880, 10.1021/bi00085a020 · DOI
  29. Ravel, 1993, Affinity-labeling of an NADPH-binding site on the heavy subunit of flavocytochrome b558 in particulate NADPH oxidase from activated human neutrophils., Biochem Biophys Res Commun, 196, 543, 10.1006/bbrc.1993.2284 · DOI
  30. Leusen, 1996, Disturbed interaction of p21-rac with mutated p67-phox causes chronic granulomatous disease., J Exp Med, 184, 1243, 10.1084/jem.184.4.1243 · DOI
  31. Sathyamoorthy, 1997, p40phox down-regulates NADPH oxidase activity through interactions with its SH3 domain., J Biol Chem, 272, 9141, 10.1074/jbc.272.14.9141 · DOI
  32. de Mendez, 1995, Functional reconstitution of the phagocyte NADPH oxidase by transfection of its multiple components in a heterologous system., Blood, 85, 1104, 10.1182/blood.V85.4.1104.bloodjournal8541104 · DOI
  33. Tsunawaki, 1996, Involvement of p40phox in activation of phagocyte NADPH oxidase through association of its carboxyl-terminal, but not its amino-terminal, with p67phox., J Exp Med, 184, 893, 10.1084/jem.184.3.893 · DOI
  34. Wientjes, 1997, Immunoelectron microscopy shows a clustered distribution of NADPH oxidase components in the human neutrophil plasma membrane., J Leukoc Biol, 61, 303, 10.1002/jlb.61.3.303 · DOI
  35. Kobayashi, 1998, Identification of intracellular sites of superoxide production in stimulated neutrophils., J Cell Sci, 111, 81, 10.1242/jcs.111.1.81 · DOI
  36. Borregaard, 1983, Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: Translocation during activation., J Cell Biol, 97, 52, 10.1083/jcb.97.1.52 · DOI · Paper page
  37. Siems, 1997, Inhibition of NADPH oxidase-mediated superoxide radical formation in PMA-stimulated human neutrophils by 4-hydroxynonenal–binding to -SH and -NH2 groups., Free Radic Res, 27, 353, 10.3109/10715769709065774 · doi:10.3109/10715769709065774
  38. Fujii, 1997, Nitric oxide inactivates NADPH oxidase in pig neutrophils by inhibiting its assembling process., J Biol Chem, 272, 32773, 10.1074/jbc.272.52.32773 · DOI · Paper page
  39. Ding, 1996, The renaturable 69- and 63-kDa protein kinases that undergo rapid activation in chemoattractant-stimulated guinea pig neutrophils are p21-activated kinases., J Biol Chem, 271, 24869, 10.1074/jbc.271.40.24869 · DOI
  40. Shi, 1996, PR-39, a proline-rich antibacterial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47phox., Proc Natl Acad Sci USA, 93, 6014, 10.1073/pnas.93.12.6014 · DOI
  41. Henderson, 1987, The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel., Biochem J, 246, 325, 10.1042/bj2460325 · DOI · Paper page
  42. Henderson, 1988, Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge., Biochem J, 255, 285
  43. Nanda, 1993, Abnormal activation of H+ conductance in NADPH oxidase-defective neutrophils., Proc Natl Acad Sci USA, 90, 760, 10.1073/pnas.90.2.760 · DOI
  44. Nanda, 1994, Assessment of the contribution of the cytochrome b moiety of the NADPH oxidase to the transmembrane H+ conductance of leukocytes., J Biol Chem, 269, 27280, 10.1016/S0021-9258(18)46981-5 · DOI
  45. Schrenzel, 1998, Electron currents generated by the human phagocyte NADPH oxidase., Nature, 392, 734, 10.1038/33725 · DOI · Paper page
  46. de Mendez, 1997, Specificity of p47phox SH3 domain interactions in NADPH oxidase assembly and activation., Mol Cell Biol, 17, 2177, 10.1128/MCB.17.4.2177 · DOI
  47. de Mendez, 1996, Multiple SH3 domain interactions regulate NADPH oxidase assembly in whole cells., EMBO J, 15, 1211, 10.1002/j.1460-2075.1996.tb00462.x · DOI
  48. De Leo, 1996, Assembly of the human neutrophil NADPH oxidase involves binding of p67phox and flavocytochrome b to a common functional domain in p47phox., J Biol Chem, 271, 17013, 10.1074/jbc.271.29.17013 · DOI
  49. Hata, 1997, Roles for proline-rich regions of p47phox and p67phox in the phagocyte NADPH oxidase activation in vitro., Biochem Biophys Res Commun, 241, 226, 10.1006/bbrc.1997.7807 · DOI
  50. de Mendez, 1994, Role of p67-phox SH3 domains in assembly of the NADPH oxidase system., J Biol Chem, 269, 16326, 10.1016/S0021-9258(17)34011-5 · DOI
  51. Callard, 1994, A method for the elimination of false positives generated by the mRNA differential display technique., BioTechniques, 16, 1096
  52. Hata, 1998, Anionic amphiphile-independent activation of the phagocyte NADPH oxidase in a cell-free system by p47(phox) and p67(phox), both in C terminally truncated forms. Implication for regulatory src homology 3 domain-mediated interactions., J Biol Chem, 273, 4232, 10.1074/jbc.273.7.4232 · DOI
  53. Wientjes, 1996, Interactions between cytosolic component of the NADPH oxidase: p40phox interacts with both p67phox and p47phox., Biochem J, 317, 919, 10.1042/bj3170919 · DOI
  54. Adams, 1997, Interaction of human neutrophil flavocytochrome b with cytosolic proteins: Transferred-NOESY NMR studies of a gp91phox C-terminal peptide bound to p47phox., Biochem J, 325, 249, 10.1042/bj3250249 · DOI
  55. Diekmann, 1994, Interaction of Rac with p67phox and regulation of phagocytic NADPH oxidase activity., Science, 265, 531, 10.1126/science.8036496 · DOI · Paper page
  56. Diekmann, 1995, Rac GTPase interacts with GAPs and target proteins through multiple effector sites., EMBO J, 14, 5297, 10.1002/j.1460-2075.1995.tb00214.x · DOI · Paper page
  57. Fuchs, 1996, Topological organization of the cytosolic activating complex of the superoxide-generating NADPH-oxidase. Pinpointing the sites of interaction between p47phox, p67phox and p40phox using the two-hybrid system., Biochim Biophys Acta, 1312, 39, 10.1016/0167-4889(96)00020-1 · DOI
  58. Sumimoto, 1996, Assembly and activation of the phagocyte NADPH oxidase. Specific interaction of the N-terminal Src homology 3 domain of p47phox with p22phox is required for activation of the NADPH oxidase., J Biol Chem, 271, 22152, 10.1074/jbc.271.36.22152 · DOI
  59. Kleinberg, 1994, p21rac does not participate in the early interaction between p47phox and cytochrome b558 that leads to phagocyte NADPH oxidase activation in vitro., Biochemistry, 33, 2490, 10.1021/bi00175a018 · DOI
  60. Prigmore, 1995, A 68-kDa kinase and NADPH oxidase component p67phox are targets for Cdc42Hs and Rac1 in neutrophils., J Biol Chem, 270, 10717, 10.1074/jbc.270.18.10717 · DOI
  61. Babior, 1997, The NADPH oxidase of leukocytes, 737
  62. Park, 1997, Activation of the leukocyte NADPH oxidase subunit p47phox by protein kinase C. A phosphorylation-dependent change in the conformation of the C-terminal end of p47phox., Biochemistry, 36, 8484
  63. Swain, 1997, Analysis of activation-induced conformational changes in p47phox using tryptophan fluorescence spectroscopy., J Biol Chem, 272, 29502, 10.1074/jbc.272.47.29502 · DOI
  64. Haskell, 1995, Analysis of signaling events associated with activation of neutrophil superoxide anion production by eosinophil granule major basic protein., Blood, 86, 4627, 10.1182/blood.V86.12.4627.bloodjournal86124627 · DOI
  65. Park, 1996, Attenuation of p47phox and p67phox membrane translocation as the inhibitory mechanism of S-nitrosothiol on the respiratory burst oxidase in human neutrophils., Biochem Biophys Res Commun, 220, 31, 10.1006/bbrc.1996.0351 · DOI
  66. Zhen, 1998, Probing the role of the carboxyl terminus of the gp91phox subunit of neutrophil flavocytochrome b558 using site-directed mutagenesis., J Biol Chem, 273, 6575, 10.1074/jbc.273.11.6575 · DOI
  67. Faust, 1995, The phosphorylation targets of p47phox, a subunit of the respiratory burst oxidase. Functions of the individual target serines as evaluated by site-directed mutagenesis., J Clin Invest, 96, 1499, 10.1172/JCI118187 · DOI · Paper page
  68. Inanami, 1998, Activation of the leukocyte NADPH oxidase by phorbol ester requires the phosphorylation of p47phox on serine S303 or S304., J Biol Chem, 273, 9539, 10.1074/jbc.273.16.9539 · DOI · Paper page
  69. El Benna, 1996, Phosphorylation of the respiratory burst oxidase subunit p47phox as determined by 2-dimensional phosphopeptide mapping. Phosphorylation by protein kinase C, protein kinase A and a mitogen-activated protein kinase (MAP-kinase)., J Biol Chem, 271, 6374, 10.1074/jbc.271.11.6374 · DOI · Paper page
  70. Johnson, 1998, Activation of p47phox, a cytosolic subunit of the leukocyte NADPH oxidase. Phosphorylation of S359 or S370 precedes phosphorylation at other sites and is required for activity., J Biol Chem, 273, 35147, 10.1074/jbc.273.52.35147 · DOI
  71. Bengis-Garber, 1996, Protein kinase A downregulates the phosphorylation of p47 phox in human neutrophils: A possible pathway for inhibition of the respiratory burst., Cell Signal, 8, 291, 10.1016/0898-6568(96)00052-6 · DOI
  72. Fuchs, 1997, The 40-kDa component of the phagocyte NADPH oxidase (p40phox) is phosphorylated during activation in differentiated HL60 cells., Eur J Biochem, 249, 531, 10.1111/j.1432-1033.1997.00531.x · DOI
  73. El Benna, 1997, Phosphorylation of the respiratory burst oxidase subunit p67phox during human neutrophil activation. Regulation by protein kinase c-dependent and independent pathways., J Biol Chem, 272, 17204, 10.1074/jbc.272.27.17204 · DOI
  74. Heyworth, 1996, Protein phosphorylation in neutrophils from patients with p67-phox–deficient chronic granulomatous disease., Blood, 87, 4404, 10.1182/blood.V87.10.4404.bloodjournal87104404 · DOI
  75. El Benna, 1994, Cytosolic guanine nucleotide-binding protein Rac2 operates in vivo as a component of the neutrophil respiratory burst oxidase. Transfer of Rac2 and the cytosolic oxidase components p47phox and p67phox to the submembranous actin cytoskeleton during oxidase activation., J Biol Chem, 269, 6729, 10.1016/S0021-9258(17)37436-7 · DOI · Paper page
  76. Quinn, 1993, Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase components., J Biol Chem, 268, 20983, 10.1016/S0021-9258(19)36882-6 · DOI · Paper page
  77. Hazan, 1997, Cytosolic phospholipase A2 and its mode of activation in human neutrophils by opsonized zymosan. Correlation between 42/44 kDa mitogen-activated protein kinase, cytosolic phospholipase A2 and NADPH oxidase., Biochem J, 326, 867, 10.1042/bj3260867 · DOI
  78. Rane, 1997, Formyl peptide receptors are coupled to multiple mitogen-activated protein kinase cascads by distinct signal transduction pathways: Role in activation of reduced nicotinamide adenine dinucleotide oxidase., J Immunol, 159, 5070, 10.4049/jimmunol.159.10.5070 · DOI
  79. Park, 1997, Kinase-dependent activation of the leukocyte NADPH oxidase in a cell-free system: Phosphorylation of membranes and p47phox during oxidase activation., J Biol Chem, 272, 11035, 10.1074/jbc.272.17.11035 · DOI
  80. McPhail, 1995, Cell-free activation of neutrophil NADPH oxidase by a phosphatidic acid-regulated protein kinase., Proc Natl Acad Sci USA, 92, 7931, 10.1073/pnas.92.17.7931 · DOI
  81. Harbecke, 1997, Desensitization of the fMLP-induced NADPH-oxidase response in human neutrophils is lacking in okadaic acid-treated cells., J Leukoc Biol, 61, 753, 10.1002/jlb.61.6.753 · DOI
  82. Gay, 1997, Phosphatase activity regulates superoxide anion generation and intracellular signaling in human neutrophils., Biochim Biophys Acta, 1336, 243, 10.1016/S0304-4165(97)00034-2 · DOI
  83. Curnutte, 1994, Reciprocal interactions between protein kinase C and components of the NADPH oxidase complex may regulate superoxide production by neutrophils stimulated with a phorbol ester., J Biol Chem, 269, 10813, 10.1016/S0021-9258(17)34132-7 · DOI
  84. Zhang, 1992, Heterogeneous amino acids in Ras and Rap1A specifying sensitivity to GAP proteins., Science, 254, 1630, 10.1126/science.1749934 · DOI
  85. Kleinberg, 1990, The phagocyte 47-kilodalton cytosolic oxidase protein is an early reactant in activation of the respiratory burst., J Biol Chem, 265, 15577, 10.1016/S0021-9258(18)55436-3 · DOI
  86. Kwong, 1993, Regulation of the human neutrophil NADPH oxidase by rho-related G-proteins., Biochemistry, 32, 5711, 10.1021/bi00072a029 · DOI
  87. Maly, 1994, Activated or dominant inhibitory mutants of Rap1A decrease the oxidative burst of Epstein-Barr virus-transformed human B lymphocytes., J Biol Chem, 269, 18743, 10.1016/S0021-9258(17)32230-5 · DOI
  88. Bokoch, 1991, Inhibition of Rap 1A binding to cytochrome b558 of NADPH oxidase by phosphorylation of Rap 1A., Science, 254, 1794, 10.1126/science.1763330 · DOI
  89. Schmid, 1996, Enhancement of protein kinase C-dependent O2-production in Epstein-Barr virus-transformed B lymphocytes by p120Ras-GAP antisense oligonucleotide., J Biol Chem, 271, 9320, 10.1074/jbc.271.16.9320 · doi:10.1074/jbc.271.16.9320
  90. Nori, 1992, Regulation of tetradecanoyl phorbol acetate-induced responses in NIH 3T3 cells by GAP, the GTPase-activating protein associated with p21 c-ras., Mol Cell Biol, 12, 936, 10.1128/MCB.12.3.936 · DOI
  91. Nauseef, 1991, Assembly of the neutrophil respiratory burst oxidase. Protein kinase C promotes cytoskeletal and membrane association of cytosolic oxidase components., J Biol Chem, 266, 5911, 10.1016/S0021-9258(19)67684-2 · DOI · Paper page
  92. Yan, 1995, Tumor necrosis factor triggers redistribution to a Triton X-100-insoluble, cytoskeletal fraction of beta 2 integrins, NADPH oxidase components, tyrosine phosphorylated proteins, and the protein tyrosine kinase p58fgr in human neutrophils adherent to fibrinogen., J Leukoc Biol, 58, 595, 10.1002/jlb.58.5.595 · DOI
  93. Zhou, 1994, CR3 (Mac-1, alpha M beta 2, CD11b/CD18) and Fc gamma RIII cooperate in generation of a neutrophil respiratory burst: Requirement for Fc gamma RIII and tyrosine phosphorylation., J Cell Biol, 125, 1407, 10.1083/jcb.125.6.1407 · DOI · Paper page
  94. Zhou, 1993, Leukocyte response integrin and integrin-associated protein act as a signal transduction unit in generation of a phagocyte respiratory burst., J Exp Med, 178, 1165, 10.1084/jem.178.4.1165 · DOI
  95. Grogan, 1997, Cytosolic phox proteins interact with and rgulate the assembly of coronin in neutrophils., J Cell Sci, 110, 3071, 10.1242/jcs.110.24.3071 · DOI
  96. Heyworth, 1997, Cofilin undergoes rapid dephosphorylation in stimulated neutrophils and translocates to ruffled membranes enriches in products of the NADPH oxidase complex. Evidence for a novel cycle of phosphorylation and dephosphorylation., Histochem Cell Biol, 108, 221, 10.1007/s004180050162 · doi:10.1007/s004180050162
  97. Morimatsu, 1997, Actin enchances the activation of human neutrophil NADPH oxidase in a cell-free system., Biochem Biophys Res Commun, 230, 206, 10.1006/bbrc.1996.5881 · DOI
  98. Lowell, 1996, Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions., J Cell Biol, 133, 895, 10.1083/jcb.133.4.895 · DOI · Paper page
  99. Yan, 1996, Regulation of Src family tyrosine kinase activities in adherent human neutrophils—Evidence that reactive oxygen intermediates produced by adherent neutrophils increase the activity of the p58c-fgr and p53/56lyn tyrosine kinases., J Biol Chem, 271, 23464, 10.1074/jbc.271.38.23464 · DOI
  100. Kume, 1994, Retrovirus-mediated reconstitution of respiratory burst activity in X-linked chronic granulomatous disease cells., Blood, 84, 3311, 10.1182/blood.V84.10.3311.3311 · DOI
  101. Ding, 1996, High-level reconstitution of respiratory burst activity in a human X-linked chronic granulomatous disease (X-CGD) cell line and correction of murine X-CGD bone marrow cells by retroviral-mediated gene transfer of human gp91phox., Blood, 88, 1834, 10.1182/blood.V88.5.1834.1834 · DOI
  102. Weil, 1997, Genetic correction of p67phox deficient chronic granulomatous disease using peripheral blood progenitor cells as a target for retrovirus mediated gene transfer., Blood, 89, 1754, 10.1182/blood.V89.5.1754 · DOI
  103. Björgvinsdóttir, 1997, Retroviral-mediated gene transfer of gp91phox into bone marrow cells rescues defect in host defense against Aspergillus fumigatus in murine X-linked chronic granulomatous disease., Blood, 89, 41, 10.1182/blood.V89.1.41 · doi:10.1182/blood.v89.1.41
  104. Tanabe, 1997, Phorbol 12-myristate 13-acetate (PMA)-induced oxyradical production in rheumatoid synovial cells., Jpn J Pharmacol, 73, 347, 10.1254/jjp.73.347 · doi:10.1254/jjp.73.347
  105. Babior, 1982, The production of superoxide by neutrophils, 157
  106. Jones, 1996, Expression of phagocyte NADPH oxidase components in human endothelial cells., Am J Physiol Heart Circ Physiol, 271, H1626, 10.1152/ajpheart.1996.271.4.H1626 · DOI · Paper page
  107. Marumo, 1997, Platelet-derived growth factor-stimulated superoxide anion production modulates activation of transcription factor NF-kappaB and expression of monocyte chemoattractant protein 1 in human aortic smooth muscle cells., Circulation, 96, 2361, 10.1161/01.CIR.96.7.2361 · DOI · Paper page
  108. Laursen, 1997, Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension., Circulation, 95, 588, 10.1161/01.CIR.95.3.588 · DOI · Paper page
  109. Hiran, 1997, Detection of superoxide and NADPH oxidase in porcine articular chondrocytes., Free Radic Biol Med, 23, 736, 10.1016/S0891-5849(97)00054-3 · DOI
  110. Bachmann, 1997, Immunohistochemical colocalization of the alpha-subunit of neutrophil NADPH oxidase and ecto-5′-nucleotidase in kidney and liver., Kidney Int, 51, 479, 10.1038/ki.1997.66 · DOI
  111. Wang, 1996, NADPH-oxidase and a hydrogen peroxide-sensitive K+ channel may function as an oxygen sensor complex in airway chemoreceptors and small cell lung carcinoma cell lines., Proc Natl Acad Sci USA, 93, 13182, 10.1073/pnas.93.23.13182 · doi:10.1073/pnas.93.23.13182
  112. Chandra, 1997, Measurement of Ca2+ fluxes during elicitation of the oxidative burst in aequorin-transformed tobacco cells., J Biol Chem, 272, 28274, 10.1074/jbc.272.45.28274 · DOI
  113. Shatwell, 1996, The FRE1 ferric reductase of Saccharomyces cerevisiae is a cytochrome b similar to that of NADPH oxidase., J Biol Chem, 271, 14240, 10.1074/jbc.271.24.14240 · DOI

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Metadata

Authors
Babior, B. M.
Venue
Blood
Published
1999-03-01
Volume
93
Issue
5
Pages
1464-1476
ISSN
  • 0006-4971 (ISSN-L)
  • 1528-0020
OpenAlex
W1586099293
Cited by
2,134
References
4
FWCI
37.17
Type
journal article
Language
en
Open access
closed

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