Effectiveness of pharmacist intervention for asthma control improvement
Open accessAbstract
Education on optimal medication use is an essential strategy to improve asthma control. The current authors investigated whether pharmacist interventions, focused on appropriate use of asthma medication and tailor-made to the patient's current asthma control, would improve asthma control in adult patients. A 6-month randomised, controlled, parallel-group trial was conducted in 66 community pharmacies in Belgium. Patients were randomly assigned to receive usual pharmacist care (n = 94) or a pre-defined pharmacist intervention (n = 107). This intervention mainly focused on improving inhalation technique and medication adherence. Primary outcome was the level of asthma control, as assessed by the Asthma Control Test® (ACT). Mean ACT scores did not change from baseline for both study groups. However, a pre-defined subgroup analysis of patients having insufficiently controlled asthma at baseline showed that the intervention had significantly increased the ACT score after 6 months compared with usual care. The intervention also reduced, for the complete study group, reliever medication use and the frequency of night-time awakenings due to asthma. Inhalation technique and adherence to controller medication were significantly better in the intervention group. In conclusion, pragmatic community pharmacy-based programmes can significantly improve therapeutic outcomes in adult asthma patients.
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In Mehuys et al., a subgroup analysis of patients having insufficiently controlled asthma at baseline showed the intervention group had significantly increased ACT scores after six months (mean ACT change +2.3 in intervention and +0.3 in control; mean difference 2.0, 95% CI: 0.1, 3.9; p = 0.038).
“a subgroup analysis of patients having insufficiently controlled asthma at baseline showed the intervention group had significantly increased ACT scores after six months (mean ACT change from baseline in the intervention group was +2.3 and +0.3 in the control group (mean difference 2.0, 95% CI: 0.1, 3.9; p = 0.038).”
From Helping patients help themselves: A systematic review of self-management support strategies in primary health care practice (2019) · cites this paper as [81]
In Mehuys et al., the need for rescue medication was reduced in both groups from baseline, with a significantly higher reduction in the intervention group (-0.56 and -0.57 inhalations per day at three and six-month follow-up) than control (-0.03 and -0.43 inhalations per day; p = 0.012).
“The need for rescue medication was reduced in both groups from baseline, however a significantly higher reduction in the intervention group (-0.56 and -0.57 inhalations per day at three and six-month follow-up, respectively) was reported against control (-0.03 and -0.43 inhalations per day at three and six-month follow-up, respectively; p = 0.012)”
From Helping patients help themselves: A systematic review of self-management support strategies in primary health care practice (2019) · cites this paper as [81]
Three RCTs reported on the level of asthma control and symptoms.
“Three RCTs reported on the level of asthma control and symptoms”
From Helping patients help themselves: A systematic review of self-management support strategies in primary health care practice (2019) · cites this paper as [81]
Nine studies reported disease knowledge as an outcome.
“Nine studies reported disease knowledge as an outcome [52, 66–68, 71, 81, 82, 88, 93, 111].”
From Helping patients help themselves: A systematic review of self-management support strategies in primary health care practice (2019) · cites this paper as [81]
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- Authors
- Mehuys, E., Van Bortel, L., De Bolle, L., Van Tongelen, I., Annemans, L., Remon, J. P., & Brusselle, G.
- Affiliations
- Ghent University Hospital (BE)
- Corresponding author
- Mehuys, E.
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2007-12-19
- Volume
- 31
- Issue
- 4
- Pages
- 790-799
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W2159371369
- Cited by
- 218
- References
- 33
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 8 · 2023: 13 · 2022: 15 · 2021: 18 · 2020: 12 · 2019: 14 · 2018: 10 · 2017: 14 · 2016: 12 · 2015: 12 · 2014: 18 · 2013: 12 · 2012: 15
- FWCI
- 9.23
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Respiratory Journal (publishedVersion)
- PubMed (publishedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion)
- VUBIR (Vrije Universiteit Brussel) (submittedVersion)
- Funders
- GlaxoSmithKline
- Universitair Ziekenhuis Gent
- Universiteit Gent
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacy and Medical Practices
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Keywords
- asthma control, pharmacist intervention, community pharmacy, inhaler technique, medication adherence, controller medications, rescue medication, Asthma Control Test, adult asthma patients, patient education
- MeSH terms
- Administration, Inhalation, Adult, Asthma, Community Pharmacy Services, Female, Humans, Male, Middle Aged, Patient Compliance, Patient Education as Topic, Pharmacists, Self Administration, Severity of Illness Index, Anti-Asthmatic Agents
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