The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Interferon-γ release assays for the diagnosis of active tuberculosis: a systematic review and meta-analysis
Open accessAbstract
Interferon-γ release assays (IGRAs) are now established for the immunodiagnosis of latent infection with Mycobacterium tuberculosis in many countries. However, the role of IGRAs for the diagnosis of active tuberculosis (TB) remains unclear. Following preferred reporting items for systematic reviews and meta-analyses (PRISMA) and quality assessment of diagnostic accuracy studies (QUADAS) guidelines, we searched PubMed, EMBASE and Cochrane databases to identify studies published in January 2001–November 2009 that evaluated the evidence of using QuantiFERON-TB® Gold in-tube (QFT-G-IT) and T-SPOT.TB®directly on blood or extrasanguinous specimens for the diagnosis of active TB. The literature search yielded 844 studies and 27 met the inclusion criteria. In blood and extrasanguinous fluids, the pooled sensitivity for the diagnosis of active TB was 80% (95% CI 75–84%) and 48% (95% CI 39–58%) for QFT-G-IT, and 81% (95% CI 78–84%) and 88% (confirmed and unconfirmed cases) (95% CI 82–92%) for T-SPOT.TB®, respectively. In blood and extrasanguinous fluids, the pooled specificity was 79% (95% CI 75–82%) and 82% (95% CI 70–91%) for QFT-G-IT, and 59% (95% CI 56–62%) and 82% (95% CI 78–86%) for T-SPOT.TB®, respectively. Although the diagnostic sensitivities of both IGRAs were higher than that of tuberculin skin tests, it was still not high enough to use as a rule out test for TB. Positive evidence for the use of IGRAs in compartments other than blood will require more independent and carefully designed prospective studies.
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Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Whiting, P., Rutjes, A. W., Reitsma, J. B., Bossuyt, P. M., & Kleijnen, J. (2003) · BMC Medical Research Methodology · doi:10.1186/1471-2288-3-25 · Cited by 3,592
Meta-DiSc: a software for meta-analysis of test accuracy data
Zamora, J., Abraira, V., Muriel, A., Khan, K., & Coomarasamy, A. (2006) · BMC Medical Research Methodology · doi:10.1186/1471-2288-6-31 · Cited by 1,883
The spectrum of latent tuberculosis: rethinking the biology and intervention strategies
Barry, C. E., Boshoff, H. I., Dartois, V., Dick, T., Ehrt, S., Flynn, J., Schnappinger, D., Wilkinson, R. J., & Young, D. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2236 · Cited by 1,422
Global tuberculosis control 2010
Behera, D. (2012) · The Indian Journal of Medical Research · Cited by 1,262
Specific immune-based diagnosis of tuberculosis
Andersen, P., Munk, M., Pollock, J., & Doherty, T. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02742-2 · Cited by 924
Evaluation of QUADAS, a tool for the quality assessment of diagnostic accuracy studies
Whiting, P. F., Weswood, M. E., Rutjes, A. W., Reitsma, J. B., Bossuyt, P. N., & Kleijnen, J. (2006) · BMC Medical Research Methodology · doi:10.1186/1471-2288-6-9 · Cited by 769
The European Centre for Disease Prevention and Control
Gouvras, G. (2004) · Eurosurveillance · doi:10.2807/esm.09.10.00478-en · Cited by 741
Cited by
Pai, M., Behr, M. A., Dowdy, D., Dheda, K., Divangahi, M., Boehme, C. C., Ginsberg, A., Swaminathan, S., Spigelman, M., Getahun, H., et al. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.76 · Cited by 1,270
Self-citationThe risk of tuberculosis in transplant candidates and recipients: a TBNET consensus statement
Bumbacea, D., Arend, S. M., Eyuboglu, F., Fishman, J. A., Goletti, D., Ison, M. G., Jones, C. E., Kampmann, B., Kotton, C. N., Lange, C., et al. (2012) · European Respiratory Journal · doi:10.1183/09031936.00000712 · Cited by 264
Self-citationTuberculosis Diagnostics and Biomarkers: Needs, Challenges, Recent Advances, and Opportunities
McNerney, R., Maeurer, M., Abubakar, I., Marais, B., Mchugh, T. D., Ford, N., Weyer, K., Lawn, S., Grobusch, M. P., Memish, Z., et al. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir860 · Cited by 191
Self-citationTuberculosis in the Head and Neck: Changing Trends and Age-Related Patterns
Gehrke, T., Hackenberg, S., Tecle, N., Hagen, R., & Scherzad, A. (2021) · The Laryngoscope · doi:10.1002/lary.29668 · Cited by 11
Metadata
- Authors
- Sester, M., Sotgiu, G., Lange, C., Giehl, C., Girardi, E., Migliori, G. B., Bossink, A., Dheda, K., Diel, R., Dominguez, J., Lipman, M., Nemeth, J., Ravn, P., Winkler, S., Huitric, E., Sandgren, A., & Manissero, D.
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2010-09-16
- Volume
- 37
- Issue
- 1
- Pages
- 100-111
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W2102099892
- Cited by
- 537
- References
- 37
- FWCI
- 5.64
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Sester, M., Sotgiu, G., Lange, C., Giehl, C., Girardi, E., Migliori, G. B., Bossink, A., Dheda, K., Diel, R., Dominguez, J., Lipman, M., Nemeth, J., Ravn, P., Winkler, S., Huitric, E., Sandgren, A., & Manissero, D. (2011). Interferon-γ release assays for the diagnosis of active tuberculosis: a systematic review and meta-analysis. European Respiratory Journal. https://doi.org/10.1183/09031936.00114810
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