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Cited by 331

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

Costs of asthma are correlated with severity: a 1-yr prospective study

Open access
Godard, P., Chanez, P., Siraudin, L., Nicoloyannis, N., Duru, G.·2002·European Respiratory Journal

Abstract

Asthma prevalence is increasing and asthma-related costs are likely to increase, but few studies have analysed the relationship of asthma costs and severity. The impact of severity on costs was quantified in a cohort of 318 asthmatic patients followed up prospectively for 1 yr. Patients presenting with a broad range of severity of the disease (intermittent, mild persistent, moderate persistent, severe persistent) were recruited by chest physicians throughout France and treated for 1 yr according to customary clinical practice and following international guidelines. Severity, direct and indirect costs, and quality of life (QoL) were assessed. A multivariate analysis was conducted to relate factors contributing to the costs measured. Mean direct costs for goods and services excluding hospitalization, numbers of consultations, supplementary examinations, and the use and cost of bronchodilators and corticosteroids, indirect costs of days lost from work, and adverse QoL parameters all increased significantly with increasing severity. This also applied to mean age, body weight, asthma duration, depression of forced expiratory volume in one second, and inhaled corticosteroid posology in the 234 patients completing the study. There was a significant relationship (r=0.614, p<0.001) between direct costs (hospitalization and cures were excluded) and three domains of the QoL questionnaire (mobility, pain and energy). Overall costs of asthma (including individual direct costs, indirect costs, and intangible quality of life costs) are clearly related to severity. This is the first study in asthma to combine rigorous independent classification of grades of severity in statistically valid numbers of patients of grades receiving “real-world” treatment and followed-up prospectively for 1 yr. It allowed severity to be accurately related to direct, indirect and intangible costs of asthma. Quality of life explained a significant part of these costs.

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Metadata

Authors
Godard, P., Chanez, P., Siraudin, L., Nicoloyannis, N., & Duru, G.
Venue
European Respiratory Journal
Published
2001-01-01
Volume
19
Issue
1
Pages
61-67
ISSN
  • 0903-1936 (ISSN-L)
  • 1399-3003
OpenAlex
W2163779250
Cited by
331
References
25
FWCI
3.32
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Costs of asthma are correlated with severity: a 1-yr prospective study. https://app.cochat.ai/papers/10.1183/09031936.02.00232001
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Godard, P., Chanez, P., Siraudin, L., Nicoloyannis, N., & Duru, G. (2002). Costs of asthma are correlated with severity: a 1-yr prospective study. European Respiratory Journal. https://doi.org/10.1183/09031936.02.00232001

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.