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The occupational burden of chronic obstructive pulmonary disease

Open access
Trupin, L., Earnest, G., San Pedro, M., Balmes, J.R., Eisner, M.D., Yelin, E., Katz, P.P., Blanc, P.D.·2003·European Respiratory Journal

Abstract

Although chronic obstructive pulmonary disease (COPD) is attributed predominantly to tobacco smoke, occupational exposures are also suspected risk factors for COPD. Estimating the proportion of COPD attributable to occupation is thus an important public health need. A randomly selected sample of 2,061 US residents aged 55–75 yrs completed telephone interviews covering respiratory health, general health status and occupational history. Occupational exposure during the longest-held job was determined by self-reported exposure to vapours, gas, dust or fumes and through a job exposure matrix. COPD was defined by self-reported physician's diagnosis. After adjusting for smoking status and demography, the odds ratio for COPD related to self-reported occupational exposure was 2.0 (95% confidence interval (CI) 1.6–2.5), resulting in an adjusted population attributable risk (PAR) of 20% (95% CI 13–27%). The adjusted odds ratio based on the job exposure matrix was 1.6 (95% CI 1.1–2.5) for high and 1.4 (95% CI 1.1–1.9) for intermediate probability of occupational dust exposure; the associated PAR was 9% (95% CI 3–15%). A narrower definition of COPD, excluding chronic bronchitis, was associated with a PAR based on reported occupational exposure of 31% (95% CI 19–41%). Past occupational exposures significantly increased the likelihood of chronic obstructive pulmonary disease, independent of the effects of smoking. Given that one in five cases of chronic obstructive pulmonary disease may be attributable to occupational exposures, clinicians and health policy-makers should address this potential avenue of chronic obstructive pulmonary disease causation and its prevention.

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Metadata

Authors
Trupin, L., Earnest, G., San Pedro, M., Balmes, J. R., Eisner, M. D., Yelin, E., Katz, P. P., & Blanc, P. D.
Venue
European Respiratory Journal
Published
2003-09
Volume
22
Issue
3
Pages
462-469
ISSN
  • 0903-1936 (ISSN-L)
  • 1399-3003
OpenAlex
W2104982541
Cited by
347
References
20
FWCI
14.35
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The occupational burden of chronic obstructive pulmonary disease. https://app.cochat.ai/papers/10.1183/09031936.03.00094203
The paper
Trupin, L., Earnest, G., San Pedro, M., Balmes, J. R., Eisner, M. D., Yelin, E., Katz, P. P., & Blanc, P. D. (2003). The occupational burden of chronic obstructive pulmonary disease. European Respiratory Journal. https://doi.org/10.1183/09031936.03.00094203

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.