Psychological factors associated with use of home nebulized therapy for COPD
Open accessAbstract
This study examined the relationship between adherence to domiciliary nebulized therapy and psychological factors; patient attitudes, anxiety, depression, and quality of life. Ninety three patients aged 45-77 yrs with chronic obstructive pulmonary disease (COPD) and using domiciliary nebulizers were recruited from a hospital database. They completed the St George's respiratory questionnaire (SGRQ)-1 and the hospital anxiety and depression scale (HADS) and attended a semistructured interview. Their usual nebulizers were replaced by Dataloggers, which record the date, time and duration of each treatment, to use for 4 weeks. The SGRQ was then repeated (SGRQ-2). Eighty two patients completed the study. Fifty six percent were poorly adherent; taking less than 70% of the dose prescribed (or less than 60% on regimens of > or = 5 times daily). The total scores on the SGRQ-2 were negatively correlated with percentage adherence. Multiple regression analysis showed that the SGRQ-2 total score was associated with percentage adherence, depression score, feeling supported by clinic staff, and patients feeling that they tried to ignore their chest disease. Patients who report poor quality of life are more likely to be depressed, feel unsupported by clinic staff and be poorly adherent to treatment. Increased levels of clinic support, with the addition of psychological treatments, may be of benefit to some patients with chronic obstructive pulmonary disease.
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Untreated and undetected anxiety and depressive symptoms may increase physical disability, morbidity, and health-care utilization.
“Untreated and undetected anxiety and depressive symptoms may increase physical disability, morbidity, and health-care utilization.”
From Anxiety and Depression in COPD (2008) · cites this paper as [22]
Untreated or incompletely treated depression and anxiety have major implications for compliance with medical treatment, increased frequency of hospital admissions, prolonged length of stay, and increased consultations with primary care physicians.
“Untreated or incompletely treated depression and anxiety have major implications for compliance with medical treatment, increased frequency of hospital admissions, prolonged length of stay, and increased consultations with primary care physicians.6,22,26”
From Anxiety and Depression in COPD (2008) · cites this paper as [22]
Depression lowers quality of life and decreases adherence to treatment in patients with COPD.
“In addition, depression lowers quality of life and decreases adherence to treatment.22,58”
From Anxiety and Depression in COPD (2008) · cites this paper as [22]
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- Authors
- Bosley, C., Corden, Z., Rees, P., & Cochrane, G.
- Affiliations
- Guy's Hospital (GB)
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 1996-11-01
- Volume
- 9
- Issue
- 11
- Pages
- 2346-2350
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W2166191793
- Cited by
- 104
- References
- 19
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 5 · 2019: 6 · 2018: 3 · 2017: 4 · 2016: 4 · 2015: 6 · 2014: 5 · 2013: 7 · 2012: 2
- FWCI
- 1.25
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Respiratory Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Inhalation and Respiratory Drug Delivery
- Keywords
- chronic obstructive pulmonary disease, medication adherence, psychological factors, depression, anxiety, quality of life, patient attitudes
- MeSH terms
- Aged, Anxiety, Depression, Female, Humans, Lung Diseases, Obstructive, Male, Middle Aged, Nebulizers and Vaporizers, Patient Compliance, Quality of Life, Surveys and Questionnaires, Regression Analysis
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