Biomarker signatures for progressive idiopathic pulmonary fibrosis

Predicting Survival in Idiopathic Pulmonary Fibrosis

KING, T. E., TOOZE, J. A., SCHWARZ, M. I., BROWN, K. R., & CHERNIACK, R. M. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.164.7.2003140 · Cited by 853 · see citing works

Changes in Clinical and Physiologic Variables Predict Survival in Idiopathic Pulmonary Fibrosis

Collard, H. R., King, T. E., Bartelson, B. B., Vourlekis, J. S., Schwarz, M. I., & Brown, K. K. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200211-1311oc · Cited by 764 · see citing works

Fibrotic Idiopathic Interstitial Pneumonia

Latsi, P. I., du Bois, R. M., Nicholson, A. G., Colby, T. V., Βisirtzoglou, D., Nikolakopoulou, A., Veeraraghavan, S., Hansell, D. M., & Wells, A. U. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200210-1245oc · Cited by 584 · see citing works

MMP1 and MMP7 as Potential Peripheral Blood Biomarkers in Idiopathic Pulmonary Fibrosis

Rosas, I. O., Richards, T. J., Konishi, K., Zhang, Y., Gibson, K., Lokshin, A. E., Lindell, K. O., Cisneros, J., MacDonald, S. D., Pardo, A., et al. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050093 · Cited by 582 · see citing works

Radiological versus histological diagnosis in UIP and NSIP: survival implications

Flaherty, K. R. (2003) · Thorax · doi:10.1136/thorax.58.2.143 · Cited by 538 · see citing works

Up-Regulation and Profibrotic Role of Osteopontin in Human Idiopathic Pulmonary Fibrosis

Pardo, A., Gibson, K. F., Cisneros, J., Richards, T. J., Yang, Y., Becerril, C., Yousem, S., Herrera, I., Ruiz, V., Selman, M., et al. (2005) · PLoS Medicine · doi:10.1371/journal.pmed.0020251 · Cited by 492 · see citing works

Peripheral blood proteins predict mortality in idiopathic pulmonary fibrosis

Richards, T. J., Kaminski, N., Baribaud, F., Flavin, S., Brodmerkel, C., Horowitz, D., Li, K., Choi, J., Vuga, L. J., Lindell, K. O., et al. (2012) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201101-0058oc · Cited by 381 · see citing works

Clinical significance of histological classification of idiopathic interstitial pneumonia

Flaherty, K. R., Toews, G. B., Travis, W. D., Colby, T. V., Kazerooni, E. A., Gross, B. H., Jain, A. K., Strawderman, R. L., Paine, R., Flint, A., et al. (2002) · European Respiratory Journal · doi:10.1183/09031936.02.00182002 · Cited by 371 · see citing works

Idiopathic Pulmonary Fibrosis: Physiologic Tests, Quantitative CT Indexes, and CT Visual Scores as Predictors of Mortality

Best, A. C., Meng, J., Lynch, A. M., Bozic, C. M., Miller, D. E., Grunwald, G. K., & Lynch, D. A. (2008) · Radiology · doi:10.1148/radiol.2463062200 · Cited by 322 · see citing works

An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study

Maher, T. M., Oballa, E., Simpson, J. K., Porte, J., Habgood, A., Fahy, W. A., Flynn, A., Molyneaux, P. L., Braybrooke, R., Divyateja, H., et al. (2017) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(17)30430-7 · Cited by 271 · see citing works

Accelerated Variant of Idiopathic Pulmonary Fibrosis: Clinical Behavior and Gene Expression Pattern

Selman, M., Carrillo, G., Estrada, A., Mejía, M. E., Becerril, C., Cisneros, J., Gaxiola, M., Pérez‐Padilla, R., Navarro, C., Richards, T. J., et al. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000482 · Cited by 270 · see citing works

Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis

Naik, P. K., Bozyk, P. D., Bentley, J. K., Popova, A. P., Birch, C. M., Wilke, C. A., Fry, C. D., White, E. S., Sisson, T. H., Tayob, N., et al. (2012) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00139.2012 · Cited by 261 · see citing works

A simple assessment of dyspnoea as a prognostic indicator in idiopathic pulmonary fibrosis

Nishiyama, O., Taniguchi, H., Kondoh, Y., Kimura, T., Kato, K., Kataoka, K., Ogawa, T., Watanabe, F., & Arizono, S. (2010) · European Respiratory Journal · doi:10.1183/09031936.00152609 · Cited by 247 · see citing works

Baseline characteristics of idiopathic pulmonary fibrosis: analysis from the Australian Idiopathic Pulmonary Fibrosis Registry

Jo, H. E., Glaspole, I., Grainge, C., Goh, N. S. L., Hopkins, P. M.-A., Moodley, Y. P., Reynolds, P. N., Chapman, S. A., Walters, E. H., Zappala, C. J., et al. (2017) · European Respiratory Journal · doi:10.1183/13993003.01592-2016 · Cited by 234 · see citing works

Molecular Phenotypes Distinguish Patients with Relatively Stable from Progressive Idiopathic Pulmonary Fibrosis (IPF)

Boon, K., Bailey, N., Yang, J., Steel, M. P., Groshong, S. D., Kervitsky, D. J., Brown, K. K., Schwarz, M. I., & Schwartz, D. A. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005134 · Cited by 183 · see citing works

Plasma surfactant protein-D, matrix metalloproteinase-7, and osteopontin index distinguishes idiopathic pulmonary fibrosis from other idiopathic interstitial pneumonias

White, E. S., Xia, M., Murray, S., Dyal, R., Flaherty, C. M., Flaherty, K. R., Moore, B. B., Cheng, L., Doyle, T. J., Villalba, J., et al. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201505-0862oc · Cited by 180 · see citing works

Blood Biomarkers in Idiopathic Pulmonary Fibrosis

Guiot, J., Moermans, C., Henket, M., Corhay, J.-L., & Louis, R. (2017) · Lung · doi:10.1007/s00408-017-9993-5 · Cited by 147 · see citing works

The role of periostin in lung fibrosis and airway remodeling

O’Dwyer, D. N., & Moore, B. B. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2649-z · Cited by 144 · see citing works

MMP-7 is a predictive biomarker of disease progression in patients with idiopathic pulmonary fibrosis

Bauer, Y., White, E. S., de Bernard, S., Cornelisse, P., Leconte, I., Morganti, A., Roux, S., & Nayler, O. (2017) · ERJ Open Research · doi:10.1183/23120541.00074-2016 · Cited by 139 · see citing works

Validation of the prognostic value of <scp>MMP</scp>‐7 in idiopathic pulmonary fibrosis

Tzouvelekis, A., Herazo‐Maya, J. D., Slade, M., Chu, J., Deiuliis, G., Ryu, C., Li, Q., Sakamoto, K., Ibarra, G., Pan, H., et al. (2017) · Respirology · doi:10.1111/resp.12920 · Cited by 130 · see citing works

Presence of a prothrombotic state in people with idiopathic pulmonary fibrosis: a population-based case–control study

Navaratnam, V. V., Fogarty, A., McKeever, T. M., Thompson, N., Jenkins, G. R., Johnson, S. R., Dolan, G., Kumaran, M., Pointon, K. S., & Hubbard, R. (2013) · Thorax · doi:10.1136/thoraxjnl-2013-203740 · Cited by 119 · see citing works

Circulating Plasma Biomarkers of Survival in Antifibrotic-Treated Patients With Idiopathic Pulmonary Fibrosis

Adegunsoye, A., Alqalyoobi, S., Linderholm, A., Bowman, W. S., Lee, C. T., Pugashetti, J. V., Sarma, N., Ma, S.-F., Haczku, A., Sperling, A., et al. (2020) · Chest · doi:10.1016/j.chest.2020.04.066 · Cited by 82 · see citing works

Review: Serum biomarkers in idiopathic pulmonary fibrosis and systemic sclerosis associated interstitial lung disease – frontiers and horizons

Jee, A. S., Sahhar, J., Youssef, P. P., Bleasel, J. F., Adelstein, S., Nguyen, M., & Corte, T. J. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2019.05.014 · Cited by 71 · see citing works

Idiopathic Pulmonary Fibrosis

Raghu, G. (1987) · CHEST Journal · doi:10.1378/chest.92.1.148 · Cited by 64 · see citing works

Six-SOMAmer Index Relating to Immune, Protease and Angiogenic Functions Predicts Progression in IPF

Ashley, S. L., Xia, M., Murray, S., O’Dwyer, D. N., Grant, E. P., White, E. S., Flaherty, K. R., Martínez, F. J., & Moore, B. B. (2016) · PLoS ONE · doi:10.1371/journal.pone.0159878 · Cited by 60 · see citing works

N-acetylcysteine inhibits IL-8 and MMP-9 release and ICAM-1 expression by bronchoalveolar cells from interstitial lung disease patients

Radomska-Leśniewska, D. M., Skopińska-Różewska, E., Jankowska-Steifer, E. A., Sobiecka, M., Sadowska, A. M., Hevelke, A., & Malejczyk, J. (2010) · Pharmacological Reports · doi:10.1016/s1734-1140(10)70250-4 · Cited by 52 · see citing works

Cell Stress Induces Upregulation of Osteopontin via the ERK Pathway in Type II Alveolar Epithelial Cells

Kato, A., Okura, T., Hamada, C., Miyoshi, S., Katayama, H., Higaki, J., & Ito, R. (2014) · PLoS ONE · doi:10.1371/journal.pone.0100106 · Cited by 37 · see citing works

Existing and emerging biomarkers for disease progression in idiopathic pulmonary fibrosis

Inchingolo, R., Varone, F., Sgalla, G., & Richeldi, L. (2018) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2019.1553620 · Cited by 37 · see citing works

Comprehensive mass spectrometry based biomarker discovery and validation platform as applied to diabetic kidney disease

Bringans, S., Ito, J., Stoll, T. M., Winfield, K., Phillips, M. R., Peters, K. E., Davis, W. A., Davis, T. M. E., & LIPSCOMBE, R. J. (2017) · EuPA Open Proteomics · doi:10.1016/j.euprot.2016.12.001 · Cited by 35 · see citing works

Implications of the diagnostic criteria of idiopathic pulmonary fibrosis in clinical practice: Analysis from the Australian Idiopathic Pulmonary Fibrosis Registry

Jo, H. E., Glaspole, I., Goh, N., Hopkins, P. M. A., Moodley, Y., Reynolds, P. N., Chapman, S., Walters, E. H., Zappala, C., Allan, H., et al. (2019) · Respirology · doi:10.1111/resp.13427 · Cited by 28 · see citing works

Protein Network Analysis Identifies Changes in the Level of Proteins Involved in Platelet Degranulation, Proteolysis and Cholesterol Metabolism Pathways in AECOPD Patients

Tan, D. B. A., Ito, J., Peters, K. E., Livk, A., LIPSCOMBE, R. J., Casey, T. M., & Moodley, Y. P. (2020) · COPD Journal of Chronic Obstructive Pulmonary Disease · doi:10.1080/15412555.2019.1711035 · Cited by 12 · see citing works

Idiopathic pulmonary fibrosis: state of the art for 2023

Podolanczuk, A. J., Thomson, C. C., Remy-Jardin, M., Richeldi, L., Martinez, F. J., Kolb, M., & Raghu, G. (2023) · European Respiratory Journal · doi:10.1183/13993003.00957-2022 · Cited by 359 · see citing works

Matrix Metalloproteinases and Their Inhibitors in Pulmonary Fibrosis: EMMPRIN/CD147 Comes into Play

Chuliá‐Peris, L., Carreres-Rey, C., Gabasa, M., Alcaraz, J., Carretero, J., & Pereda, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23136894 · Cited by 121 · see citing works

Pulmonary fibrosis: pathogenesis and therapeutic strategies

Wang, J., Li, K., Hao, D., Li, X., Zhu, Y., Yu, H., & Chen, H. (2024) · MedComm · doi:10.1002/mco2.744 · Cited by 119 · see citing works

Emerging roles of ferroptosis in pulmonary fibrosis: current perspectives, opportunities and challenges

Hu, Y., Huang, Y., Zong, L., Lin, J., Liu, X., & Ning, S. (2024) · Cell Death Discovery · doi:10.1038/s41420-024-02078-0 · Cited by 75 · see citing works

Proteomic Biomarkers of Survival in Idiopathic Pulmonary Fibrosis

Oldham, J. M., Huang, Y., Bose, S., Ma, S.-F., Kim, J. S., Schwab, A., Ting, C., Mou, K., Lee, C. T., Adegunsoye, A., et al. (2024) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202301-0117oc · Cited by 72 · see citing works

Pulmonary fibrosis: Emerging diagnostic and therapeutic strategies

Selvarajah, B., Platé, M., & Chambers, R. C. (2023) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2023.101227 · Cited by 57 · see citing works

The critical role of osteopontin (OPN) in fibrotic diseases

Tang, Z., Xia, Z., Wang, X., & Liu, Y. (2023) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2023.08.007 · Cited by 47 · see citing works

Cluster analysis of blood biomarkers to identify molecular patterns in pulmonary fibrosis: assessment of a multicentre, prospective, observational cohort with independent validation

Fainberg, H. P., Moodley, Y. P., Isaac Triguero, A., Corte, T. J., Sand, J. M. B., Leeming, D. J., Karsdal, M. A., Wells, A. U., Renzoni, E. A., Mackintosh, J. A., et al. (2024) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(24)00147-4 · Cited by 34 · see citing works

Circulating metabolic profile in idiopathic pulmonary fibrosis: data from the IPF-PRO Registry

Summer, R. S., Todd, J. L., Neely, M. L., Lobo, L. J., Namen, A. M., Newby, L. K., Shafazand, S., Suliman, S. A., Heßlinger, C., Keller, S., et al. (2024) · Respiratory Research · doi:10.1186/s12931-023-02644-7 · Cited by 32 · see citing works

Molecular and Genetic Biomarkers in Idiopathic Pulmonary Fibrosis: Where Are We Now?

Tomos, I. P., Roussis, I., Matthaiou, A. Μ., & Dimakou, K. (2023) · Biomedicines · doi:10.3390/biomedicines11102796 · Cited by 32 · see citing works

Multi-center evaluation of baseline neutrophil-to-lymphocyte (NLR) ratio as an independent predictor of mortality and clinical risk stratifier in idiopathic pulmonary fibrosis

Mikolasch, T., George, P. M., Sahota, J., Nancarrow, T., Barratt, S. L., Woodhead, F., Kouranos, V., Cope, V. S. A., Creamer, A. W., Fidan, S., et al. (2022) · EClinicalMedicine · doi:10.1016/j.eclinm.2022.101758 · Cited by 30 · see citing works

Bioactive lipid lysophosphatidic acid species are associated with disease progression in idiopathic pulmonary fibrosis

Neighbors, M., Li, Q., Zhu, S., Liu, J., Wong, W. R., Jia, G., Sandoval, W. N., & Tew, G. W. (2023) · Journal of Lipid Research · doi:10.1016/j.jlr.2023.100375 · Cited by 26 · see citing works

Predictive biomarkers of disease progression in idiopathic pulmonary fibrosis

Zhu, W., Liu, C., Tan, C., & Zhang, J. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e23543 · Cited by 27 · see citing works

Biological and pharmacological roles of pyroptosis in pulmonary inflammation and fibrosis: recent advances and future directions

Liu, Y., Wang, D., Liu, X., Yuan, H., Liu, D., Hu, Y., & Ning, S. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01966-3 · Cited by 23 · see citing works

Architecting the metabolic reprogramming survival risk framework in LUAD through single-cell landscape analysis: three-stage ensemble learning with genetic algorithm optimization

Sun, X., Nong, M.-Y., Meng, F., Xiaojuan, S., Jiang, L., Li, Z., & Zhang, P. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05138-2 · Cited by 23 · see citing works

Biomarkers of Fibrosis in Patients with COVID-19 One Year After Hospital Discharge: A Prospective Cohort Study

Mulet, A., Tarrasó, J., Rodríguez-Borja, E., Carbonell-Asins, J., Lope-Martínez, A., Martí-Martínez, A., Murria, R., Safont, B., Fernández-Fabrellas, E., Ros, J., et al. (2023) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2022-0474oc · Cited by 17 · see citing works

Long‐term exposure to low concentrations of air pollution and decline in lung function in people with idiopathic pulmonary fibrosis: Evidence from Australia

Zheng, Q., Cox, I. A., Leigh, L., de Graaff, B., Johnston, F. H., Corte, T. J., Knibbs, L. D., Otáhal, P., Navaratnam, V. V., Campbell, J. A., et al. (2023) · Respirology · doi:10.1111/resp.14552 · Cited by 22 · see citing works

From COVID to fibrosis: lessons from single-cell analyses of the human lung

Justet, A., Zhao, A., & Kaminski, N. (2022) · Human Genomics · doi:10.1186/s40246-022-00393-0 · Cited by 21 · see citing works

Acute Exacerbations of Interstitial Lung Diseases: Focus on Biomarkers

Drakopanagiotakis, F., Markart, P., & Steiropoulos, P. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241210196 · Cited by 21 · see citing works

Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis

Uehara, Y., Tanaka, Y., Zhao, S., Nikolaidis, N. M., Pitstick, L. B., Wu, H., Yu, J. J., Zhang, E. Y., Hasegawa, Y., Noel, J. G., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-36810-8 · Cited by 20 · see citing works

The immune mechanisms of acute exacerbations of idiopathic pulmonary fibrosis

Chen, T., Sun, W., & Xu, Z. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1450688 · Cited by 19 · see citing works

Contemporary Concise Review 2021: Interstitial lung disease

McCarthy, C., & Keane, M. P. (2022) · Respirology · doi:10.1111/resp.14278 · Cited by 17 · see citing works

Research Progress of Fibroblasts in Human Diseases

Li, X., Li, N., Wang, Y., Han, Q., & Sun, B. (2024) · Biomolecules · doi:10.3390/biom14111478 · Cited by 19 · see citing works

Novel diagnostic techniques in interstitial lung disease

Glenn, L. M., Troy, L. K., & Corte, T. J. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1174443 · Cited by 17 · see citing works

Prognostic Value of Serum Biomarkers in Patients with Idiopathic Pulmonary Fibrosis in Relation to Disease Progression

Domvri, K., Organtzis, I., Apostolopoulos, A., Fouka, E., Kontakiotis, T., & Papakosta, D. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13091307 · Cited by 15 · see citing works

Pre‐Treatment MMP7 Predicts Progressive Idiopathic Pulmonary Fibrosis in Antifibrotic Treated Patients

Li, R. M., Tan, D. B. A., Tedja, C., Cooper, W. A., Jo, H. E., Grainge, C., Glaspole, I., Goh, N. S. L., Ellis, S. J., Hopkins, P. M.-A., et al. (2025) · Respirology · doi:10.1111/resp.14894 · Cited by 14 · see citing works

Acute exacerbation of idiopathic pulmonary fibrosis a narrative review primary focus on treatments

Luo, X., & Xiang, F. (2024) · Journal of Thoracic Disease · doi:10.21037/jtd-23-1565 · Cited by 16 · see citing works

Deciphering the cellular and molecular landscape of pulmonary fibrosis through single-cell sequencing and machine learning

Zhou, Y., Tong, Z., Zhu, X., Wu, C., Zhou, Y., & Dong, Z. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-024-06031-8 · Cited by 12 · see citing works

Osteopontin: an essential regulatory protein in idiopathic pulmonary fibrosis

Zhu, X., Ji, J., & Han, X.-D. (2023) · Journal of Molecular Histology · doi:10.1007/s10735-023-10169-y · Cited by 9 · see citing works

Osteopontin as a Biomarker in Interstitial Lung Diseases

Fernandez, D. I., Pulito‐Cueto, V., Cuesta, V. M. M., Remuzgo‐Martínez, S., Pargada, D. J. F., Genre, F., Alonso‐Lecue, P., López‐Mejías, R., Atienza‐Mateo, B., González-Gay, M. Á., et al. (2024) · Biomedicines · doi:10.3390/biomedicines12051108 · Cited by 9 · see citing works

A Simple Ratio in a Complex Disease: Exploring the Neutrophil-to-Lymphocyte Ratio in Idiopathic Pulmonary Fibrosis

Monteleone, G., Passantino, L., Simonetti, J., Iovene, B., Varone, F., Cameli, P., Sgalla, G., & Richeldi, L. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14145100 · Cited by 9 · see citing works

Present and future perspectives in early diagnosis and monitoring for progressive fibrosing interstitial lung diseases

Stanel, S. C., & Rivera‐Ortega, P. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1114722 · Cited by 8 · see citing works

Circulating biomarkers and progression of idiopathic pulmonary fibrosis: data from the INMARK trial

Maher, T. M., Jenkins, R. G., Cottin, V., Nishioka, Y., Noth, I., Selman, M., Song, J. W., Ittrich, C., Diefenbach, C., Stowasser, S., et al. (2024) · ERJ Open Research · doi:10.1183/23120541.00335-2023 · Cited by 7 · see citing works

The fibronectin-targeting PEG-FUD imaging probe shows enhanced uptake during fibrogenesis in experimental lung fibrosis

Harr, T. J., Gupta, N., Rahar, B., Stott, K., Medina-Guevara, Y., Gari, M. K., Oler, A. T., McDermott, I., Lee, H. J., Rasoulianboroujeni, M., et al. (2025) · Respiratory Research · doi:10.1186/s12931-025-03107-x · Cited by 7 · see citing works

Treatable traits in interstitial lung disease: a narrative review

Harrison, M., Lawler, C., Lake, F., Navaratnam, V. V., Fermoyle, C. C., Moodley, Y. P., & Corte, T. J. (2025) · Therapeutic Advances in Respiratory Disease · doi:10.1177/17534666251335774 · Cited by 7 · see citing works

Proteomics in interstitial lung disease: new insights into pathogenesis, diagnosis and treatment

Paul, P., Dasgupta, S., Roychowdhury, S., Unnithan, S., Dasgupta, H., Sen, S., Madan, K., & Chaudhury, K. (2025) · Respiratory Medicine · doi:10.1016/j.rmed.2025.108487 · Cited by 6 · see citing works

A novel mutation (p.Y24N) in NHP2 leads to idiopathic pulmonary fibrosis and lung carcinoma chronic obstructive lung disease by disrupting the expression and nucleocytoplasmic localization of NHP2

Liu, L., Sheng, Y., Wang, C.-Y., Liu, X., Guo, T., Peng, H., Luo, H., & Fan, L. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166692 · Cited by 6 · see citing works

Interleukin-7 receptor activation in interstitial macrophages promotes lung fibrosis through secreted phosphoprotein 1

Shirakawa, K., Sano, M., Sakane, I., Yamanoi, K., Kusumoto, D., Goto, S., Moriyama, H., Daigo, K., Sugai, K., Katsumata, Y., et al. (2025) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2025-0254oc · Cited by 5 · see citing works

A serum biomarker-based index for predicting progressive pulmonary fibrosis in patients with anti-synthetase syndrome: the LOCCM index

Zhu, L., Wu, S., Zong, C., Chen, Y., Sun, C., Zhang, Y., Zhang, X., Shu, X., Lü, X., Wang, G., et al. (2025) · Respiratory Research · doi:10.1186/s12931-025-03414-3 · Cited by 5 · see citing works

Establishment and application of the BRP prognosis model for idiopathic pulmonary fibrosis

Cheng, X., Feng, Z., Pan, B., Liu, Q., Han, Y., Zou, L., Rong, P., & Meng, J. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04668-5 · Cited by 5 · see citing works

Predicting and Treating Pulmonary Fibrosis with Proteomic Biomarker Investigations

Raineri, G., Samarelli, A. V., Tonelli, R., Masciale, V., Aramini, B., Petrachi, T., Bruzzi, G., Gozzi, F., Trasforini, E., Esposito, A., et al. (2025) · Biomedicines · doi:10.3390/biomedicines13112656 · Cited by 4 · see citing works

A multidimensional classifier to support lung transplant referral in patients with pulmonary fibrosis

Pugashetti, J. V., Kim, J. S., Combs, M. P., Ma, S., Adegunsoye, A., Linderholm, A., Strek, M. E., Chen, C., Dilling, D. F., Whelan, T. P. M., et al. (2024) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2024.03.018 · Cited by 4 · see citing works

PET imaging of platelet derived growth factor receptor β in lung fibrosis

Wegrzyniak, O., Lechi, F., Rokka, J., Mitran, B., Zhang, B., Thelander, U., Löfblom, J., Frejd, F. Y., Korsgren, O., Perchiazzi, G., et al. (2025) · EJNMMI Radiopharmacy and Chemistry · doi:10.1186/s41181-025-00366-3 · Cited by 5 · see citing works

Single-cell transcriptomic analysis of blood and bronchoalveolar lavage fluid in progressive fibrosing interstitial lung diseases

Sakashita, A., Hirano, A., Fujii, W., Bassler, K. E., Tsuji, T., Kadoya, M., Omoto, A., Hiraoka, N., Imabayashi, T., Kaneko, Y., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-17374-7 · Cited by 4 · see citing works

Contemporary Concise Review 2022: Interstitial lung disease

Smith, D. J. F., & Jenkins, G. R. (2023) · Respirology · doi:10.1111/resp.14511 · Cited by 4 · see citing works

Proteomic profiling of formalin-fixed paraffine-embedded tissue reveals key proteins related to lung dysfunction in idiopathic pulmonary fibrosis

Samarelli, A. V., Tonelli, R., Raineri, G., Bruzzi, G., Andrisani, D., Gozzi, F., Marchioni, A., Costantini, M., Fabbiani, L., Genovese, F., et al. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2023.1275346 · Cited by 4 · see citing works

Proteomic profiling of the extracellular matrix in skeletal muscle

Swandulla, D., & Ohlendieck, K. (2025) · Advances in clinical chemistry · doi:10.1016/bs.acc.2025.06.008 · Cited by 3 · see citing works

Circulating biomarkers in subjects with progressive pulmonary fibrosis: data from the INBUILD trial

Maher, T. M., Jenkins, G. R., Bonella, F., Assassi, S., Diefenbach, C., Ittrich, C., Rohr, K. B., & Kolb, M. (2025) · ERJ Open Research · doi:10.1183/23120541.00158-2025 · Cited by 4 · see citing works

Differential Effects of Antifibrotic Treatment on Outcome Prediction via Serial Matrix Metalloproteinase-Degraded C-Reactive Protein Neoepitope Levels in Idiopathic Pulmonary Fibrosis

Seeliger, B., Ruwisch, J., Sand, J. M. B., Simões, F. B., Jessen, H., Boerner, E. B., Fuge, J., Sewald, K., Welte, T., Wendel‐Garcia, P. D., et al. (2025) · CHEST Journal · doi:10.1016/j.chest.2025.08.047 · Cited by 3 · see citing works

Large scale plasma proteomic profiles improve prediction of idiopathic pulmonary fibrosis in general population

Zhou, R., Li, G., Zhong, Q., Li, X., Liu, Y.-X., Zheng, J., Huang, H., & Wu, X. (2025) · Respiratory Research · doi:10.1186/s12931-025-03418-z · Cited by 2 · see citing works

Machine Learning Reveals Ets2 as a Novel Target for Membranous Nephropathy Treatment and Its Role in Immune Infiltration

Wan, P., Xu, T., Tian, B., Guo, G., Li, X., & Yao, L. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.813329 · Cited by 2 · see citing works

Research on the potential mechanism of Deapioplatycodin D against pulmonary fibrosis based on bioinformatics and experimental verification

Li, C., Abdurehim, A., Zhao, S., Sun, Q., Xu, J., Xie, J., & Zhang, Y. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176603 · Cited by 2 · see citing works

Predictive factors of mortality in patients with idiopathic pulmonary fibrosis treated with antifibrotics: a novel prognostic scoring system.

Polat, G., Özdemir, Ö., Ermin, S., Unat, D. S., & Üçsular, F. D. (2024) · Sarcoidosis vasculitis and diffuse lung diseases · doi:10.36141/svdld.v41i2.13779 · Cited by 2 · see citing works

Diagnostic potential of genomic blood biomarkers of pulmonary fibrosis in a prospective cohort

He, D. X., Shannon, C. P., Hirota, J. A., Ask, K., Ryerson, C. J., & Tebbutt, S. J. (2024) · PLoS ONE · doi:10.1371/journal.pone.0314876 · Cited by 2 · see citing works

Blood urea nitrogen-to-albumin ratio as a new prognostic indicator of 1-year all-cause mortality in patients with IPF

Ge, S., Li, Y., Li, R., Liu, J., Zhang, R., Fu, H., Tang, J., Zhang, J., Zhang, N., & Zhang, M. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2024.1497530 · Cited by 2 · see citing works

Periostin and rheumatic diseases: early insights from a systematic review and meta-analysis

Mangoni, A. A., & Zinellu, A. (2025) · Clinical and Experimental Medicine · doi:10.1007/s10238-025-01615-0 · Cited by 2 · see citing works

CD206 and dust particles are prognostic biomarkers of progressive fibrosing interstitial lung disease associated with air pollutant exposure

Kadushkin, A. G., Yudina, O., Lukashevich, N., Davidovskaya, Е. I., Filanyuk, V., Dziadzichkina, V. V., & Cai, X. (2025) · Scientific Reports · doi:10.1038/s41598-025-93221-z · Cited by 2 · see citing works

Bioinformatic Analyses of Potential Key Genes in the Pathogenesis of Idiopathic Pulmonary FibrosisPreprint

Wang, P., Shu, W., Yin, F., Zhang, Q., Yin, Y., Deng, Q., Zeng, F., Li, Y., & Zhang, J. (2022) · Research Square · doi:10.21203/rs.3.rs-1646754/v1 · Cited by 2 · see citing works

Point‐of‐Care Diagnostics for Rapid Disease Detection

Bhuiyan, N. H., & Hossain, M. K. (2025) · Wiley eBooks · doi:10.1002/9781394314133.ch1 · Cited by 2 · see citing works

A survival analysis of idiopathic pulmonary fibrosis in the context of antifibrotic therapy in Saudi Arabia

Khan, M. A., Ghamdi, B. A., Alhamadi, M., Rajendram, R., Alyami, S., Al-Gamedi, M., Al-Harbi, A., & Al-Jahdali, H. H. (2023) · Annals of Thoracic Medicine · doi:10.4103/atm.atm_264_22 · Cited by 1 · see citing works

PCR array analysis reveals a novel expression profile of ferroptosis-related genes in idiopathic pulmonary fibrosis

Shen, C., Wang, W. T., Wei, D., Yang, X., Jiang, C., Sheng, Y., Chen, Y., Sun, J., Li, X. A., Li, G., et al. (2025) · BMC Pulmonary Medicine · doi:10.1186/s12890-025-03555-7 · Cited by 1 · see citing works

AI-driven target discovery and clinical development of candidate drugs for idiopathic pulmonary fibrosis: A review

Wang, D., Jing, Y., Zang, D., Zhang, C., & Yu, X. (2025) · Letters in Drug Design & Discovery · doi:10.1016/j.lddd.2025.100194 · Cited by 1 · see citing works

A new perspective on idiopathic pulmonary fibrosis research: From multi-dimensional mechanistic exploration to advances in precision therapy

Zhang, S.-M., Huang, M.-Z., Wang, Y.-W., Wang, X.-F., Ding, Y., Li, J. Q., Zou, X.-M., & Ma, C. (2026) · Respiratory Medicine · doi:10.1016/j.rmed.2026.108946 · Cited by 1 · see citing works

Hotspots and Frontiers of Host Immune Response in Idiopathic Pulmonary Fibrosis: A Bibliometric and Scientific Visual Research from 2000 to 2022

Li, S., Zhao, P., Wang, C., Xia, Y. Q., Wang, H., & Qi, W. (2023) · Journal of Immunology Research · doi:10.1155/2023/4835710 · Cited by 1 · see citing works

Efficacy of Pirfenidone According to Dose in Patients with Idiopathic Pulmonary Fibrosis: A Prospective, Observational, Single-Center Cohort Study

Lee, H. Y., Jung, S. Y., Jang, J. H., Ko, J., Kim, D.-W., Her, M., & Lee, J. H. (2023) · Life · doi:10.3390/life13112118 · Cited by 1 · see citing works

Clustering-aided prediction of outcomes in patients with idiopathic pulmonary fibrosis

Wang, L., Wu, P., Liu, Y., Patel, D. C., Leonard, T. B., & Zhao, H. (2024) · Respiratory Research · doi:10.1186/s12931-024-03015-6 · Cited by 1 · see citing works

Retrospective Analysis of Predictive Biomarkers of Survival in Acute Exacerbation of Fibrosing Interstitial Lung Disease: A Single-Center Study in Spain

Ferreiro‐Posse, A., Granados, G. D., Salvador, S., Pilia, M. F., Espejo, D., Mesones, C. E. R., Ojanguren, Í., Muñoz, X., & Villar, A. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14061974 · Cited by 1 · see citing works

Intercellular Communication and Epigenetic State of Ligand-Receptor Pairs in Systemic Sclerosis-Associated Interstitial Lung DiseasePreprint

Xu, W., Zhao, Y., Li, X., Yan, S., Liu, B., Huang, M., Ma, Z., & Yang, Q. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4819254 · Cited by 1 · see citing works

Multi-center evaluation of baseline neutrophil:lymphocyte (NLR) ratio as an independent predictor of mortality and clinical risk stratifier in Idiopathic Pulmonary FibrosisPreprint

Mikolasch, T., George, P. M., Sahota, J., Nancarrow, T., Barratt, S. L., Woodhead, F., Kouranos, V., Cope, V. S. A., Creamer, A. W., Fidan, S., et al. (2022) · medRxiv · doi:10.1101/2022.04.29.22274470

SOX9-regulated matrix proteins predict poor outcomes in patients with COVID-19 and pulmonary fibrosisPreprint

Pearmain, L., Jokl, E. J., Simpson, K., Birchall, L., Ou, Y., Lawless, C., Simpson, A., Mann, L., Scott, N. A., Shah, R. D., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.01.21.576509

The Analysis of Proteomics by Machine Learning in Separating Idiopathic Pulmonary Fibrosis from Connective Tissue Disease–Interstitial Lung Disease

Moodley, Y. P. (2024) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202403-0603ed

Developing an IPF Prognostic Model and Screening for Key Genes Based on Cold Exposure-Related Genes Using Bioinformatics Approaches

Luo, P., Gu, Q., Wang, J., Meng, X., & Zhao, M. (2025) · Biomedicines · doi:10.3390/biomedicines13030690

The Future of Precision Medicine in Interstitial Lung Disease

Adams, T. N., Patel, C., & Gulati, M. (2025) · Respiratory medicine · doi:10.1007/978-3-031-87183-2_11

Assessment of Matrix Metalloproteinases a Prognostic Indicator in Advanced Fibrotic Lung Disease: A Systematic Review

Aqil, M., Rahman, S. U., Aslam, M. Z., Ahmed, M. A. A., Ahmed, A., Javaid, S., & Haq, E. U. (2025) · Pakistan Journal of Medicine and Dentistry · doi:10.36283/ziun-pjmd14-2/059

The clinical utility of elevated monocyte count in patients with fibrotic interstitial lung disease

Min, B., Marinescu, D.-C., Assayag, D., Fisher, J. H., Khalil, N., Kolb, M. R. J., Manganas, H., Marcoux, V. S., Fahy, W. A., Johnson, S. R., et al. (2025) · ERJ Open Research · doi:10.1183/23120541.00259-2025

Additional file 1 of Circulating metabolic profile in idiopathic pulmonary fibrosis: data from the IPF-PRO Registry

Summer, R. S., Todd, J. L., Neely, M. L., Lobo, L. J., Namen, A. M., Newby, L. K., Shafazand, S., Suliman, S. A., Heßlinger, C., Keller, S., et al. (2024) · Figshare · doi:10.6084/m9.figshare.25067232

Additional file 1 of Establishment and application of the BRP prognosis model for idiopathic pulmonary fibrosis

Cheng, X., Feng, Z., Pan, B., Liu, Q., Han, Y., Zou, L., Rong, P., & Meng, J. (2023) · Figshare · doi:10.6084/m9.figshare.24548150

Combined antagonism of Oncostatin M (OSM) and Interleukin 6 (IL-6) provides both anti-fibrotic and anti-inflammatory benefit in pulmonary fibrosisPreprint

Ratsimandresy, R. A., Doran, E., Dengler, H. S., Headland, S. E., Wedeles, C. J., Guidi, R., Xu, D., Liu, J., Shi, Y., Wang, J., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.25.695625

Intercellular communication landscape and its working mechanism in systemic sclerosis–associated interstitial lung disease

Huang, M., Zhang, Y., Yang, Y., Gao, W., Yang, W., Li, X., Zhang, J., Ma, Z., Yang, Q., & Xu, W. (2026) · Lara D. Veeken · doi:10.1093/rheumatology/keag098

Bioinformatics and machine learning identify ITIH4 and ZC3H13 as novel mRNA biomarkers for major depressive disorder that promote microglial M1 polarization

Kong, D., Zheng, Y., Li, Z., Cai, F., He, J., & Sun, X. (2026) · Cytotechnology · doi:10.1007/s10616-026-00923-x

Multi-omics reveals the effects and mechanisms of Xinxue Granules against idiopathic pulmonary fibrosis through activating the cAMP/EPAC/CREB axis

Zhang, X., Li, H., Zhang, K., Shi, Y., Huang, Q., Guo, D., Zhang, X., Zhai, B., Yang, X., Luan, F., et al. (2026) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2026.122062

Global landscape for pulmonary fibrosis treatment: a data-driven perspective from clinical trials

Zhao, C., Song, C., Zhou, Y., Luo, J., Zheng, S., Li, X., Dang, Y., Yang, N., & Kong, J. (2026) · BMC Pulmonary Medicine · doi:10.1186/s12890-026-04340-w

Honokiol regulates Acute respiratory distress syndrome (ARDS)‐associated pulmonary fibrosis via the miR‐19a‐3p/POSTN axis

Liu, W., Wang, H.-H., Kuo, H., Yen, C., Hua, M. D.-S., Chang, C.-Y., Xu, Z., Liu, I., Hsieh, C. C., Hsu, C., et al. (2026) · British Journal of Pharmacology · doi:10.1111/bph.70580

Markers of microvascular instability predict severity and survival in idiopathic pulmonary fibrosis

Csordas, D. J., Ma, S., Huang, Y., Receveur, B. A., Strickland, E., Cucuzzella, L. C., Pugashetti, J. V., Lee, C. T., Podolanczuk, A. J., Martínez, F. J., et al. (2026) · Thorax · doi:10.1136/thorax-2026-225147

Pirfenidone exerts anti-inflammatory effects by inhibiting CXCL6 to alleviate idiopathic pulmonary fibrosis

Sun, G., Sun, L., Jiang, J., Ma, X., Zhong, Y., Li, H., Liu, X., Xue, K., Hu, X., Feng, J., et al. (2026) · International Immunopharmacology · doi:10.1016/j.intimp.2026.117430

Advances in prognostic assessment of idiopathic pulmonary fibrosis: From clinical-physiological parameters and molecular biomarkers to multimodal models

Zheng, Y., Zhu, W., Wu, Y., 杜玲杰, Zhao, R., Xu, B., Yan, F., & Tan, C. (2026) · Respiratory Medicine · doi:10.1016/j.rmed.2026.109187

Late Breaking Abstract - Novel Prognostic Biomarkers in Idiopathic Pulmonary Fibrosis: A Proteomic Study

Ruwisch, J., Röcken, J., Geiselmann, A., Azim, A., Bauer, Y., & Prasse, A. (2025) · doi:10.1183/13993003.congress-2025.pa6338

Idiopathic Pulmonary Fibrosis

Raghu, G., Richeldi, L., Jagerschmidt, A., Martin, V., Subramaniam, A., Ozoux, M., Espéret, C., & Soubrane, C. (2018) · CHEST Journal · doi:10.1016/j.chest.2018.08.1083 · Cited by 95 · see citing works

Six-SOMAmer Index Relating to Immune, Protease and Angiogenic Functions Predicts Progression in IPF

Ashley, S. L., Xia, M., Murray, S., O’Dwyer, D. N., Grant, E. P., White, E. S., Flaherty, K. R., Martínez, F. J., & Moore, B. B. (2016) · PLoS ONE · doi:10.1371/journal.pone.0159878 · Cited by 60 · see citing works

Proteomic profiling for the development of new serum based diagnostic and prognostic biomarkers in Progressive Pulmonary Fibrosis.

Puxeddu, E., Cillis, G., Calzetta, L., Cavalli, F., Sergiacomi, G., Rossi, I., & Rogliani, P. (2022) · 12.01 - Idiopathic interstitial pneumonias · doi:10.1183/13993003.congress-2022.3661

P050 Prognostically predictive biomarkers for IPF; a longitudinal cohort study of treatment naive patients

Nicol, L. M., Mills, R., Seth, S., MacKinnon, A. C., McFarlane, P., Wallace, W. A., Stewart, G. A., Howie, S., Dhaliwal, K., Murchison, J. T., et al. (2016) · QJM · doi:10.1093/qjmed/hcw124.022