The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Costs of attention deficit–hyperactivity disorder (ADHD) in the US: excess costs of persons with ADHD and their family members in 2000
Abstract
OBJECTIVE: The objective of this study is to provide a comprehensive estimate of the cost of ADHD by consider ing the healthcare and work loss costs of persons with ADHD, as well as those costs imposed on their family members. METHODS: Excess per capita healthcare (medical and prescription drug) and work loss (disability and work absence) costs of treated ADHD patients (ages 7 years-44 years) and their family members (under 65 years of age) were calculated using administrative claims data from a single large company; work loss costs are from disability data or imputed for medically related work loss days. Excess costs are the additional costs of patients and their family members over and above those of comparable control individuals. The excess costs of untreated individuals with ADHD and their family members were also estimated. All per capita costs were extrapolated using published prevalence and treatment rates and population data; the prevalence of persons with ADHD was based upon the literature. RESULTS: The total excess cost of ADHD in the US in 2000 was $31.6 billion. Of this total, $1.6 billion was for the ADHD treatment of patients, $12.1 billion was for all other healthcare costs of persons with ADHD, $14.2 billion was for all other healthcare costs of family members of persons with ADHD, and $3.7 billion was for the work loss cost of adults with ADHD and adult family members of persons with ADHD. CONCLUSION: The annual cost of ADHD in the US is substantial. Both treated and untreated persons with ADHD, as well as their family members, impose consider able economic burdens on the healthcare system as a result of this condition. While these first estimates of the cost of ADHD to the nation are suggestive of its substantial economic burden, future research needs to refine and build on this analysis, particularly in the context of a model to control for related co-morbidities. Similarly, since these results are based on data from a single company for the period 1996-1998, the analysis should be validated with more representative, current data.
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“The economic burden of untreated adult ADHD has been increasingly studied and shows the same pattern as in children, with higher than normal costs of sickness leave, less productivity, more accidents and more health care costs [141,319,320].”
From European consensus statement on diagnosis and treatment of adult ADHD: The European Network Adult ADHD (2010) · cites this paper as [319]
Citations
Cites
Statistical Abstract of the U nited S tates
(2005) · Wiley eBooks · doi:10.1002/0471667196.ess2527 · Cited by 8,872
BARKLEY, R. A., FISCHER, M., EDELBROCK, C. S., & SMALLISH, L. (1990) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199007000-00007 · Cited by 1,507
Biederman, J. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.816 · Cited by 1,498
The Economic Burden of Depression in the United States: How Did It Change Between 1990 and 2000?
Greenberg, P. E., Kessler, R. C., Birnbaum, H. G., Leong, S. A., Lowe, S. W., Berglund, P. A., & Corey-Lisle, P. K. (2003) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v64n1211 · Cited by 1,280
Self-citationBarkley, R. A., Fischer, M., Smallish, L., & Fletcher, K. (2002) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.111.2.279 · Cited by 1,199
Committee on Quality Improvement, S. O. A.-D. D. (2000) · Pediatrics · doi:10.1542/peds.105.5.1158 · Cited by 1,076
Greenberg, P. E., Stiglin, L. E., Finkelstein, S. N., & Berndt, E. R. (1994) · PharmacoResources · doi:10.1007/bf03289581 · Cited by 975
Self-citationAdult psychiatric status of hyperactive boys grown up
Mannuzza, S., Klein, R. G., Bessler, A., Malloy, P., & LaPadula, M. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.4.493 · Cited by 769
WEISS, G., HECHTMAN, L., MILROY, T., & PERLMAN, T. (1985) · Journal of the American Academy of Child Psychiatry · doi:10.1016/s0002-7138(09)60450-7 · Cited by 753
Attention deficit hyperactivity disorder adults: Comorbidities and adaptive impairments
Murphy, K., & Barkley, R. A. (1996) · Comprehensive Psychiatry · doi:10.1016/s0010-440x(96)90022-x · Cited by 700
Research works printed but not linked: 11
- American Psychiatric Association, 2003, Fact
- Weiss M, 2003, Can Med Assoc J, 168, 715
- Barkley RA, 2002, J Clin Psychiatry, 63, 10
- Nechmad A, 2000, Israel J Psychiatry Rel Sci, 37, 3
- Kelleher KJ, 2001, Healthcare costs for children with attention-deficit/hyperactivity disorder. TEN: Trends Evidence-Based Neuropsychiatry, 3, 60
- Rice DP, 1985, San Francisco, CA: Institute for Health and Aging, University of California
- Greenberg PE, 1993, J Clin Psychiatry, 54, 405
- US, 2000, Washington (DC): US Bureau of the Census
- US, 2000, Washington (DC): US Bureau of the Census
- Barnett A, 2000, Am J Managed Care, 6, 1243
- Hodgson TA, 1999, Health Care Financ Rev, 21, 119
Cited by
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Pallanti, S., & Salerno, L. (2020) · Springer eBooks · doi:10.1007/978-3-030-39051-8_1 · Cited by 1
Zeidler, J. (2016) · Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz · doi:10.1007/s00103-016-2327-6 · Cited by 1
Pharmacological treatment and prognosis of ADHD
Elia, J., Kingsley, R. S., Lam, C., Takeda, T., de Berardinis, R., Laracy, S. D., Sackett, J. C., Tang, S.-C., Schardt, M., Nivus, K., et al. (2013) · doi:10.2217/ebo.13.229 · Cited by 1
Ehrmann, D. E. (2009) · Deep Blue (University of Michigan)
Psykologiska behandlingar för vuxna med ADHD
Hirvikoski, T. (2013) · Socialmedicinsk tidskrift · doi:10.62607/smt.v90i3.43292
Ramírez, G. M. G., Miramón, I. P. Z., & Farfán, M. I. R. (2011) · instname:Universidad del Rosario
Evolution of stress in families of children with attention deficit hyperactivity disorder
Guerro-Prado, D., Mardomingo-Sanz, M. L., Ortiz-Guerra, J. J., García-García, P., & Soler-López, B. (2015) · Anales de Pediatría (English Edition) · doi:10.1016/j.anpede.2015.09.020
Trampush, J. W. (2010) · CUNY Academic Works (City University of New York)
Surman, C. B. H., Hammerness, P. G., & Miller, K. (2009) · Current Attention Disorders Reports · doi:10.1007/s12618-009-0018-z
Children with ADHD in a rural community
Miller, D. J. (2005) · Montana State University ScholarWorks (Montana State University)
Alliance and Mechanisms of Medication Adherence in Pediatric Psychiatric Practice
Nadai, D., & Stevens, A. (2013)
Williams, Y. S. (2011) · UKnowledge (University of Kentucky)
Lide, B. L. (2013) · Texas ScholarWorks (Texas Digital Library)
Modafinil for the Treatment of Attention Deficit Hyperactivity Disorder: A Systematic Review
Lee, Y. J. (2010) · Korean Journal of Clinical Pharmacy
Maternal obesity, gestational weight gain, and child cognition, behavior, and academic achievement
Pugh, S. J. (2015) · D-Scholarship@Pitt (University of Pittsburgh)
Attention-Deficit/Hyperactivity Disorder, Stress, and Quality of Life in Adulthood
Combs, M. A. (2014) · NC Digital Online Collection of Knowledge and Scholarship (The University of North Carolina at Greensboro) · doi:10.71889/5fylantbak.29859647
Employment Acquisition, Work Productivity, and Job Retention
London, J. B., Molinero, A. M., & McCue, M. P. (2011)
Shaikh, M. A., & Shaikh, I. A. (2006) · PubMed
Adult ADHD: Effects on Student Performance Within the Online Classroom
Barnett-Braddock, F. (2016) · Digital Commons (Liberty University)
On Worry – psychiatry in literature
Kapanee, A. R. M. (2018) · The British Journal of Psychiatry · doi:10.1192/bjp.2018.114
Quesada, D. (2018) · FIU - Digital Commons (Florida International University) · doi:10.25148/etd.fidc006868
Arranz, F. J., & Ros, S. (2007) · Wiley eBooks · doi:10.1002/9783527619337.ch17
Methylmercury and Measures of Attention Deficits in the ELEMENT Cohort.
Tutino, R. C. (2015) · Deep Blue (University of Michigan)
Kooij, J. J. S. (2021) · Springer eBooks · doi:10.1007/978-3-030-82812-7_1
Kooij, J. J. S. (2012) · Springer eBooks · doi:10.1007/978-1-4471-4138-9_1
(2010) · Wiley eBooks · doi:10.1002/9781444328172.refs
The impact of ADHD genetic risk on educational achievement: a comparative cross-national study
Dannemann, B. C., & Gören, E. (2022) · Oxford Economic Papers · doi:10.1093/oep/gpac019
باقبص, ح. ع. (2024) · المجلة العربية لعلوم الإعاقة والموهبة · doi:10.21608/jasht.2024.337381
(2025) · Wiley eBooks · doi:10.1002/9781118941430.refs
Lyster, S., Bjerkeset, O. A., Bjørngaard, J. H., Nilsen, S. M., & Asheim, A. (2025) · Research Square · doi:10.21203/rs.3.rs-8133858/v1
van Stralen, J., Gill, S. K., Reaume, C. J., & Handelman, K. (2021) · Figshare · doi:10.6084/m9.figshare.16735689
Igarashi, A., Nishigaki, N., Kawakita, Y., & Tsujii, N. (2026) · BMC Psychiatry · doi:10.1186/s12888-026-07953-x
Adamou, M., & Wright, E. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1884417
Metadata
- Authors
- Birnbaum, H. G., Kessler, R. C., Lowe, S. W., Secnik, K., Greenberg, P. E., Leong, S. A., & Swensen, A. R.
- Affiliations
- Analysis Group (United States) (US)
- Harvard University (US)
- Eli Lilly (United States) (US)
- Corresponding author
- Birnbaum, Howard G.
- Venue
- Current Medical Research and Opinion
- Publisher
- Informa UK Limited
- Published
- 2005-02
- Volume
- 21
- Issue
- 2
- Pages
- 195-205
- ISSN
- 0300-7995 (ISSN-L)
- 1473-4877
- OpenAlex
- W2111117333
- Cited by
- 237
- References
- 55
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 4 · 2023: 3 · 2022: 6 · 2021: 12 · 2020: 5 · 2019: 11 · 2018: 10 · 2017: 13 · 2016: 4 · 2015: 11 · 2014: 14 · 2013: 24 · 2012: 22
- FWCI
- 9.06
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Medical Research and Opinion (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Eli Lilly and Company
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- attention deficit hyperactivity disorder, economic burden of disease, health care costs, work loss costs, relatives of patients, untreated ADHD, prescription drug costs, disability, absenteeism, economic burden
- MeSH terms
- Adolescent, Adult, Attention Deficit Disorder with Hyperactivity, Child, Family, Female, Humans, Male, Middle Aged, United States, Prevalence, Case-Control Studies, Health Care Costs, Cost of Illness
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