The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Phylogenetic analysis of fungal ABC transporters
Open accessAbstract
BACKGROUND: The superfamily of ABC proteins is among the largest known in nature. Its members are mainly, but not exclusively, involved in the transport of a broad range of substrates across biological membranes. Many contribute to multidrug resistance in microbial pathogens and cancer cells. The diversity of ABC proteins in fungi is comparable with those in multicellular animals, but so far fungal ABC proteins have barely been studied. RESULTS: We performed a phylogenetic analysis of the ABC proteins extracted from the genomes of 27 fungal species from 18 orders representing 5 fungal phyla thereby covering the most important groups. Our analysis demonstrated that some of the subfamilies of ABC proteins remained highly conserved in fungi, while others have undergone a remarkable group-specific diversification. Members of the various fungal phyla also differed significantly in the number of ABC proteins found in their genomes, which is especially reduced in the yeast S. cerevisiae and S. pombe. CONCLUSIONS: Data obtained during our analysis should contribute to a better understanding of the diversity of the fungal ABC proteins and provide important clues about their possible biological functions.
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Multidrug resistance in cancer: role of ATP–dependent transporters
Gottesman, M. M., Fojo, T., & Bates, S. E. (2002) · Nature Reviews Cancer · doi:10.1038/nrc706 · Cited by 5,536
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
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Cited by
Dermauw, W., & Van Leeuwen, T. (2014) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2013.11.001 · Cited by 631
Kang, J., Park, J., Choi, H., Burla, B., Kretzschmar, T., Lee, Y., & Martinoia, E. (2011) · The Arabidopsis Book · doi:10.1199/tab.0153 · Cited by 573
Yeast ATP-Binding Cassette Transporters Conferring Multidrug Resistance
Prasad, R., & Goffeau, A. (2012) · Annual Review of Microbiology · doi:10.1146/annurev-micro-092611-150111 · Cited by 221
Multidrug resistance in fungi: regulation of transporter-encoding gene expression
Paul, S., & Moye-Rowley, W. S. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00143 · Cited by 137
Wasi, M., Khandelwal, N. K., Moorhouse, A. J., Nair, R., Vishwakarma, P., Bravo Ruiz, G., Ross, Z. K., Lorenz, A., Rudramurthy, S. M., Chakrabarti, A., et al. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01445 · Cited by 89
Metadata
- Authors
- Kovalchuk, A., & Driessen, A. J.
- Venue
- BMC Genomics
- Published
- 2010
- Volume
- 11
- Issue
- 1
- Pages
- 177
- ISSN
- 1471-2164 (ISSN-L)
- OpenAlex
- W2126870177
- Cited by
- 228
- References
- 6
- FWCI
- 5.41
- Type
- journal article
- Language
- en
- Open access
- gold
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