The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Anorexia nervosa is linked to reduced brain structure in reward and somatosensory regions: a meta-analysis of VBM studies
Open accessAbstract
Background: Structural imaging studies demonstrate brain tissue abnormalities in eating disorders, yet a quantitative analysis has not been done. Methods: In global and regional meta-analyses of 9 voxel-based morphometry (VBM) studies, with a total of 228 eating disorder participants (currently ill with anorexia nervosa), and 240 age-matched healthy controls, we compare brain volumes using global and regional analyses. Results: Anorexia nervosa (AN) patients have global reductions in gray (effect size = −0.66) and white matter (effect size = −0.74) and increased cerebrospinal fluid (effect size = 0.98) and have regional decreases in left hypothalamus, left inferior parietal lobe, right lentiform nucleus and right caudate, and no significant increases. No significant difference in hemispheric lateralization was found. Conclusions: Global and regional meta-analyses suggest that excessive restrained eating as found in those with anorexia nervosa coincides with structural brain changes analogous to clinical symptoms.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Voxel-Based Morphometry—The Methods
Ashburner, J., & Friston, K. J. (2000) · NeuroImage · doi:10.1006/nimg.2000.0582 · Cited by 8,676
ALE meta-analysis: controlling the false discovery rate and performing statistical contrasts
Laird, A. R., Fox, P. M., Price, C. J., Glahn, D. C., Uecker, A. M., Lancaster, J. L., Turkeltaub, P. E., Kochunov, P., & Fox, P. T. (2005) · Human Brain Mapping · doi:10.1002/hbm.20136 · Cited by 868
Laird, A. R. (2009) · Frontiers in Neuroinformatics · doi:10.3389/neuro.11.023.2009 · Cited by 372
Brooks, S., Prince, A., Stahl, D., Campbell, I. C., & Treasure, J. (2011) · Clinical Psychology Review · doi:10.1016/j.cpr.2010.09.006 · Cited by 236 · cited 3×
“We present no average T score showing gray matter increase (only 1 study reported increase in the right DLPFC, Brooks et al., 2011).”
BackgroundSelf-citationVan den Eynde, F., Suda, M., Broadbent, H., Guillaume, S., Van den Eynde, M., Steiger, H., Israel, M., Berlim, M., Giampietro, V., Simmons, A., et al. (2012) · European Eating Disorders Review · doi:10.1002/erv.1163 · Cited by 132
Friederich, H.-C., Walther, S., Bendszus, M., Biller, A., Thomann, P., Zeigermann, S., Katus, T., Brunner, R., Zastrow, A., & Herzog, W. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2011.09.042 · Cited by 119
McCormick, L. M., Keel, P. K., Brumm, M. C., Bowers, W., Swayze, V., Andersen, A., & Andreasen, N. (2008) · International Journal of Eating Disorders · doi:10.1002/eat.20549 · Cited by 114
Cited by
The Science Behind the Academy for Eating Disorders' Nine Truths About Eating Disorders
Schaumberg, K., Welch, E., Breithaupt, L., Hübel, C., Baker, J. H., Munn‐Chernoff, M. A., Yilmaz, Z., Ehrlich, S., Mustelin, L., Ghaderi, A., et al. (2017) · European Eating Disorders Review · doi:10.1002/erv.2553 · Cited by 266
The neural crossroads of psychiatric illness: an emerging target for brain stimulation
Downar, J., Blumberger, D. M., & Daskalakis, Z. J. (2016) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2015.10.007 · Cited by 166
Fear as a translational mechanism in the psychopathology of anorexia nervosa
Murray, S. B., Strober, M., Craske, M. G., Griffiths, S., Levinson, C. A., & Strigo, I. A. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.10.013 · Cited by 75
Lao-Kaim, N. P., Fonville, L., Giampietro, V. P., Williams, S. C. R., Simmons, A., & Tchanturia, K. (2015) · PLOS ONE · doi:10.1371/journal.pone.0124027 · Cited by 79
Brooks, S. J., Burch, K. H., Maiorana, S. A., Cocolas, E., Schioth, H. B., Nilsson, E. K., Kamaloodien, K., & Stein, D. J. (2016) · NeuroImage: Clinical · doi:10.1016/j.nicl.2016.08.019 · Cited by 50
Self-citation
Metadata
- Authors
- Titova, O. E., Hjorth, O. C., Schiöth, H. B., & Brooks, S. J.
- Venue
- BMC Psychiatry
- Published
- 2013-04-09
- Volume
- 13
- Issue
- 1
- Pages
- 110-110
- ISSN
- 1471-244X (ISSN-L)
- OpenAlex
- W2098449157
- Cited by
- 210
- References
- 7
- FWCI
- 3.64
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Anorexia nervosa is linked to reduced brain structure in reward and somatosensory regions: a meta-analysis of VBM studies. https://app.cochat.ai/papers/10.1186/1471-244x-13-110
- The paper
- Titova, O. E., Hjorth, O. C., Schiöth, H. B., & Brooks, S. J. (2013). Anorexia nervosa is linked to reduced brain structure in reward and somatosensory regions: a meta-analysis of VBM studies. BMC Psychiatry. https://doi.org/10.1186/1471-244x-13-110
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
