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The DOI matches its Crossref record; 106 of the 106 references it cites were found in a registry or an index.

Review and classification of variability analysis techniques with clinical applications

Open access
Bravi, Andrea, Longtin, André, Seely, Andrew JE·2011·BioMedical Engineering OnLine

Abstract

Analysis of patterns of variation of time-series, termed variability analysis, represents a rapidly evolving discipline with increasing applications in different fields of science. In medicine and in particular critical care, efforts have focussed on evaluating the clinical utility of variability. However, the growth and complexity of techniques applicable to this field have made interpretation and understanding of variability more challenging. Our objective is to provide an updated review of variability analysis techniques suitable for clinical applications. We review more than 70 variability techniques, providing for each technique a brief description of the underlying theory and assumptions, together with a summary of clinical applications. We propose a revised classification for the domains of variability techniques, which include statistical, geometric, energetic, informational, and invariant. We discuss the process of calculation, often necessitating a mathematical transform of the time-series. Our aims are to summarize a broad literature, promote a shared vocabulary that would improve the exchange of ideas, and the analyses of the results between different studies. We conclude with challenges for the evolving science of variability analysis.

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Metadata

Authors
Bravi, A., Longtin, A., & Seely, A. J.
Venue
BioMedical Engineering OnLine
Published
2011
Volume
10
Issue
1
Pages
90
ISSN
1475-925X (ISSN-L)
OpenAlex
W2167263515
Cited by
265
References
106
FWCI
12.71
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Review and classification of variability analysis techniques with clinical applications. https://app.cochat.ai/papers/10.1186/1475-925x-10-90
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Bravi, A., Longtin, A., & Seely, A. J. (2011). Review and classification of variability analysis techniques with clinical applications. BioMedical Engineering OnLine. https://doi.org/10.1186/1475-925x-10-90

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.