The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Biodegradable magnesium-based screw clinically equivalent to titanium screw in hallux valgus surgery: short term results of the first prospective, randomized, controlled clinical pilot study
Open accessAbstract
Purpose: Nondegradable steel-and titanium-based implants are commonly used in orthopedic surgery. Although they provide maximal stability, they are also associated with interference on imaging modalities, may induce stress shielding, and additional explantation procedures may be necessary. Alternatively, degradable polymer implants are mechanically weaker and induce foreign body reactions. Degradable magnesium-based stents are currently being investigated in clinical trials for use in cardiovascular medicine. The magnesium alloy MgYREZr demonstrates good biocompatibility and osteoconductive properties. The aim of this prospective, randomized, clinical pilot trial was to determine if magnesium-based MgYREZr screws are equivalent to standard titanium screws for fixation during chevron osteotomy in patients with a mild hallux valgus. Methods: Patients (n=26) were randomly assigned to undergo osteosynthesis using either titanium or degradable magnesium-based implants of the same design. The 6 month follow-up period included clinical, laboratory, and radiographic assessments. Results: No significant differences were found in terms of the American Orthopaedic Foot and Ankle Society (AOFAS) score for hallux, visual analog scale for pain assessment, or range of motion (ROM) of the first metatarsophalangeal joint (MTPJ). No foreign body reactions, osteolysis, or systemic inflammatory reactions were detected. The groups were not significantly different in terms of radiographic or laboratory results. Conclusion: The radiographic and clinical results of this prospective controlled study demonstrate that degradable magnesium-based screws are equivalent to titanium screws for the treatment of mild hallux valgus deformities.
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Cites
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In vitro corrosion of ZEK100 plates in Hank's Balanced Salt Solution
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Cited by
Wang, X., Xu, S., Zhou, S., Xu, W., Leary, M., Choong, P., Qian, M., Brandt, M., & Xie, Y. M. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.01.012 · Cited by 2,121
Biomimetic porous scaffolds for bone tissue engineering
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Bone biomaterials and interactions with stem cells
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Biodegradable magnesium-based implants in orthopedics-a general review and perspectives
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Metadata
- Authors
- Windhagen, H., Radtke, K., Weizbauer, A., Diekmann, J., Noll, Y., Kreimeyer, U., Schavan, R., Stukenborg-Colsman, C., & Waizy, H.
- Venue
- BioMedical Engineering OnLine
- Published
- 2013-07-03
- Volume
- 12
- Issue
- 1
- Pages
- 62-62
- ISSN
- 1475-925X (ISSN-L)
- OpenAlex
- W2116506624
- Cited by
- 521
- References
- 11
- FWCI
- 23.10
- Type
- journal article
- Language
- en
- Open access
- gold
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- Windhagen, H., Radtke, K., Weizbauer, A., Diekmann, J., Noll, Y., Kreimeyer, U., Schavan, R., Stukenborg-Colsman, C., & Waizy, H. (2013). Biodegradable magnesium-based screw clinically equivalent to titanium screw in hallux valgus surgery: short term results of the first prospective, randomized, controlled clinical pilot study. BioMedical Engineering OnLine. https://doi.org/10.1186/1475-925x-12-62
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