The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Bone biomaterials and interactions with stem cells
Open accessAbstract
Bone biomaterials play a vital role in bone repair by providing the necessary substrate for cell adhesion, proliferation, and differentiation and by modulating cell activity and function. In past decades, extensive efforts have been devoted to developing bone biomaterials with a focus on the following issues: (1) developing ideal biomaterials with a combination of suitable biological and mechanical properties; (2) constructing a cell microenvironment with pores ranging in size from nanoscale to submicro- and microscale; and (3) inducing the oriented differentiation of stem cells for artificial-to-biological transformation. Here we present a comprehensive review of the state of the art of bone biomaterials and their interactions with stem cells. Typical bone biomaterials that have been developed, including bioactive ceramics, biodegradable polymers, and biodegradable metals, are reviewed, with an emphasis on their characteristics and applications. The necessary porous structure of bone biomaterials for the cell microenvironment is discussed, along with the corresponding fabrication methods. Additionally, the promising seed stem cells for bone repair are summarized, and their interaction mechanisms with bone biomaterials are discussed in detail. Special attention has been paid to the signaling pathways involved in the focal adhesion and osteogenic differentiation of stem cells on bone biomaterials. Finally, achievements regarding bone biomaterials are summarized, and future research directions are proposed.
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A Multimaterial Scaffold With Tunable Properties: Toward Bone Tissue Repair
Feng, P., Wu, P., Gao, C., Yang, Y., Guo, W., Yang, W., & Shuai, C. (2018) · Advanced Science · doi:10.1002/advs.201700817 · Cited by 365
Self-citationScaffold degradation in bone tissue engineering: An overview
Tajvar, S., Hadjizadeh, A., & Samandari, S. S. (2023) · International Biodeterioration & Biodegradation · doi:10.1016/j.ibiod.2023.105599 · Cited by 291
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Metadata
- Authors
- Gao, C., Peng, S., Feng, P., & Shuai, C.
- Venue
- Bone Research
- Published
- 2017-12-21
- Volume
- 5
- Issue
- 1
- Pages
- 17059-17059
- ISSN
- 2095-4700 (ISSN-L)
- 2095-6231
- OpenAlex
- W2780315214
- Cited by
- 720
- References
- 9
- FWCI
- 24.33
- Type
- journal article
- Language
- en
- Open access
- gold
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- Gao, C., Peng, S., Feng, P., & Shuai, C. (2017). Bone biomaterials and interactions with stem cells. Bone Research. https://doi.org/10.1038/boneres.2017.59
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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