The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
The effects of time-released garlic powder tablets on multifunctional cardiovascular risk in patients with coronary artery disease
Open accessAbstract
The double-blinded placebo-controlled randomized study has been performed in 51 coronary heart disease (CHD) patients to estimate the effects of time-released garlic powder tablets Allicor on the values of 10-year prognostic risk of acute myocardial infarction (fatal and non-fatal) and sudden death, with the respect of secondary CHD prevention. It has been demonstrated that 12-month treatment with Allicor results in the significant decrease of cardiovascular risk by 1.5-fold in men (p < 0.05), and by 1.3-fold in women. The above results were equitable also in terms of relative risks. The main effect that played a role in cardiovascular risk reduction was the decrease in LDL cholesterol by 32.9 mg/dl in men (p < 0.05), and by 27.3 mg/dl in women. Thus, the most significant effects were observed in men, while in women the decrease of cardiovascular risk appeared as a trend that might be due presumably to the insufficient sample size. Since Allicor is the remedy of natural origin, it is safe with the respect to adverse effects and allows even perpetual administration that may be crucial for the secondary prevention of atherosclerotic diseases in CHD patients.
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“Sobenin et al. [110,111] revealed that garlic administration at a dose of 300 and 60 mg/day for 12 months and 12 weeks, respectively decreased TC, TG, and LDL while increased HDL.”
From Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review (2020) · cites this paper as [111]
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- Assmann G Cullen P Schulte H Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the prospective cardiovascular Muenster (PROCAM) study Circulation 2002 105 310 5 10.1161/hc0302.102575 11804985 · DOI · Paper page
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de Araújo, I. O., & França, S. L. G. (2022) · Brazilian Journals Editora eBooks · doi:10.35587/brj.ed.0001894
Zirpoli, B. B. P., Sena, D. C., Neto, J. B. G. B., de Andrade, M. S. B., Pontes, P. A. R. D. M., & da Costa, E. G. (2022) · Brazilian Journals Editora eBooks · doi:10.35587/brj.ed.0001890
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Anjali, S., Nair, K. G. P., Mondal, S., & Mini, S. (2023) · Functional Food Science · doi:10.31989/ffs.v3i11.1256
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Clinical evaluation of safety and efficacy of biozen syrup in patients with hyperlipidemia
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Agrawal, A., Dubey, S., & Sharma, S. (2025) · Current Chemical Biology · doi:10.2174/0122127968366669250703194520
Li, L., Ahmed, I., Alotaibi, A., Shah, L., Yang, L., Zahoor, M., & Khan, M. (2026) · Journal of Functional Foods · doi:10.1016/j.jff.2026.107152
Amelioration of Glucocorticoid-Induced Dyslipidemia by Allium affine Extract in a Rat Model
Martin, C., Bernard, S., & Robert, J. (2025) · Specialty journal of Pharmacognosy Phytochemistry and Biotechnology · doi:10.51847/sv6gkxpfxn
Metadata
- Authors
- Sobenin, I. A., Pryanishnikov, V. V., Kunnova, L. M., Rabinovich, Y. A., Martirosyan, D. M., & Orekhov, A. N.
- Affiliations
- Research Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences (RU)
- Corresponding author
- Sobenin, Igor A
- Venue
- Lipids in Health and Disease
- Published
- 2010
- Volume
- 9
- Issue
- 1
- Pages
- 119
- ISSN
- 1476-511X (ISSN-L)
- PMC
- PMC2972277
- OpenAlex
- W2028736925
- Cited by
- 114
- References
- 35
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 6 · 2023: 8 · 2022: 13 · 2021: 10 · 2020: 6 · 2019: 7 · 2018: 8 · 2017: 2 · 2016: 9 · 2015: 9 · 2014: 7 · 2013: 7 · 2012: 5
- FWCI
- 6.52
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Lipids in Health and Disease (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Garlic and Onion Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Botanical Studies and Applications
- Keywords
- coronary artery disease, cardiovascular risk, secondary prevention, acute myocardial infarction, sudden death, LDL cholesterol, sex differences, atherosclerosis
- MeSH terms
- Adult, Aged, Antioxidants, Coronary Artery Disease, Double-Blind Method, Female, Garlic, Humans, Cholesterol, LDL, Male, Middle Aged, Sex Factors, Tablets, Treatment Outcome
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