The DOI matches its Crossref record; 48 of the 49 references it cites were found in a registry or an index.
Health-related quality of life as a predictor of pediatric healthcare costs: A two-year prospective cohort analysis
Open accessAbstract
Background: The objective of this study was to test the primary hypothesis that parent proxy-report of pediatric health-related quality of life (HRQL) would prospectively predict pediatric healthcare costs over a two-year period. The exploratory hypothesis tested anticipated that a relatively small group of children would account for a disproportionately large percent of healthcare costs. Methods: 317 children (157 girls) ages 2 to 18 years, members of a managed care health plan with prospective payment participated in a two-year prospective longitudinal study. At Time 1, parents reported child HRQL using the Pediatric Quality of Life Inventory™ (PedsQL™ 4.0) Generic Core Scales, and chronic health condition status. Costs, based on health plan utilization claims and encounters, were derived for 6, 12, and 24 months. Results: In multiple linear regression equations, Time 1 parent proxy-reported HRQL prospectively accounted for significant variance in healthcare costs at 6, 12, and 24 months. Adjusted regression models that included both HRQL scores and chronic health condition status accounted for 10.1%, 14.4%, and 21.2% of the variance in healthcare costs at 6, 12, and 24 months. Parent proxy-reported HRQL and chronic health condition status together defined a 'high risk' group, constituting 8.7% of the sample and accounting for 37.4%, 59.2%, and 62% of healthcare costs at 6, 12, and 24 months. The high risk group's per member per month healthcare costs were, on average, 12 times that of other enrollees' at 24 months. Conclusions: While these findings should be further tested in a larger sample, our data suggest that parent proxy-reported HRQL can be used to prospectively predict healthcare costs. When combined with chronic health condition status, parent proxy-reported HRQL can identify an at risk group of children as candidates for proactive care coordination.
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“although HRQOL has gained increasing status as a metric of treatment effectiveness.11–14,20”
From MS quality of life, depression, and fatigue improve after mindfulness training: A randomized trial (2010) · cites this paper as [20]
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Development of the EQ-5D-Y: a child-friendly version of the EQ-5D
Wille, N., Badia, X., Bonsel, G., Burström, K., Cavrini, G., Devlin, N., Egmar, A.-C., Greiner, W., Gusi, N., Herdman, M., et al. (2010) · Quality of Life Research · doi:10.1007/s11136-010-9648-y · Cited by 872
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Self-citationMS quality of life, depression, and fatigue improve after mindfulness training: A randomized trial
Grossman, P., Kappos, L., Gensicke, H., D'Souza, M., Mohr, D. C., Penner, I. K., & Steiner, C. (2010) · Neurology · doi:10.1212/wnl.0b013e3181f4d80d · Cited by 419
Generic Health-Related Quality-of-Life Assessment in Children and Adolescents
Ravens‐Sieberer, U., Erhart, M., Wille, N., Wetzel, R., Nickel, J., & Bullinger, M. (2006) · PharmacoEconomics · doi:10.2165/00019053-200624120-00005 · Cited by 391
Metadata
- Authors
- Seid, M., Varni, J. W., Segall, D., & Kurtin, P. S.
- Affiliations
- RAND Corporation (US)
- Texas A&M University System (US)
- Corresponding author
- Seid, Michael
- Venue
- Health and Quality of Life Outcomes
- Published
- 2004-09-10
- Volume
- 2
- Issue
- 1
- Pages
- 48-48
- ISSN
- 1477-7525 (ISSN-L)
- PMC
- PMC521194
- OpenAlex
- W2118612528
- Cited by
- 108
- References
- 49
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 6 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 3 · 2019: 4 · 2018: 3 · 2017: 2 · 2016: 5 · 2015: 8 · 2014: 6 · 2013: 8 · 2012: 6
- FWCI
- 10.33
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Health and Quality of Life Outcomes (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Healthcare Policy and Management
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
- Keywords
- health-related quality of life, parent proxy reporting, PedsQL 4.0, chronic disease, managed care, prospective payment, care coordination, children
- MeSH terms
- Adolescent, California, Child, Child Health Services, Child Welfare, Child, Preschool, Chronic Disease, Female, Health Status, Humans, Longitudinal Studies, Male, Managed Care Programs, Medicaid, Parents, Pediatrics, Psychometrics, Quality of Life, Health Care Costs, Sickness Impact Profile, Risk Assessment, Proxy, Children with Disabilities, Disabled Children
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